Degradation of gamma secretase activating protein by the ubiquitin-proteasome pathway

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Autophagic-lysosomal pathway is the main proteolytic system modified in the skeletal muscle of esophageal cancer patients

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Chloroquine Prevents Progression of Experimental Pulmonary Hypertension via Inhibition of Autophagy and Lysosomal Bone Morphogenetic Protein Type II Receptor Degradation

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5-Lipoxygenase gene transfer worsens memory, amyloid, and tau brain pathologies in a mouse model of alzheimer disease

(2012) Jin Chu et al.   ANNALS OF NEUROLOGY

Purification and Characterization of the Human γ-Secretase Activating Protein

(2012) Catherine L. Deatherage et al.   BIOCHEMISTRY

Proteasomal Inhibition Restores Biological Function of Mis-sense Mutated Dysferlin in Patient-derived Muscle Cells

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Lifelong Management of Amyloid-Beta Metabolism to Prevent Alzheimer's Disease

(2012) Sam Gandy   NEW ENGLAND JOURNAL OF MEDICINE

Immunohistochemical characterization of γ-secretase activating protein expression in Alzheimer's disease brains

(2011) J. Satoh et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

5-lipoxygenase as an endogenous modulator of amyloid beta formation in vivo

(2010) Jin Chu et al.   ANNALS OF NEUROLOGY

Gamma-secretase activating protein is a therapeutic target for Alzheimer’s disease

(2010) Gen He et al.   NATURE

TMP21 degradation is mediated by the ubiquitin-proteasome pathway

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Inhibition and modulation of γ-secretase for Alzheimer’s disease

(2008) Michael S. Wolfe   Neurotherapeutics