Allosteric modulation of sigma-1 receptors by SKF83959 inhibits microglia-mediated inflammation

Antiinflammatory Effects of Orientin-2″-O-Galactopyranoside on Lipopolysaccharide-Stimulated Microglia

(2014) Xiang Zhou et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Microglia and inflammation: conspiracy, controversy or control?

(2014) Adelaide Fernandes et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Neuroimmune regulation of microglial activity involved in neuroinflammation and neurodegenerative diseases

(2014) Hugo González et al.   JOURNAL OF NEUROIMMUNOLOGY

1-O-Tigloyl-1-O-deacetyl-nimbolinin B Inhibits LPS-Stimulated Inflammatory Responses by Suppressing NF-κB and JNK Activation in Microglia Cells

(2014) Li Tao et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Microglial and macrophage polarization—new prospects for brain repair

(2014) Xiaoming Hu et al.   Nature Reviews Neurology

Microglial phagocytosis of live neurons

(2014) Guy C. Brown et al.   NATURE REVIEWS NEUROSCIENCE

SKF83959 is a novel triple reuptake inhibitor that elicits anti-depressant activity

(2013) Xing Fang et al.   ACTA PHARMACOLOGICA SINICA

The sigma-1 receptor protects against cellular oxidative stress and activates antioxidant response elements

(2012) Arindam Pal et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Orteronel (TAK-700), a novel non-steroidal 17,20-lyase inhibitor: Effects on steroid synthesis in human and monkey adrenal cells and serum steroid levels in cynomolgus monkeys

(2012) Masuo Yamaoka et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Effects of the Sigma-1 Receptor Agonist 1-(3,4-Dimethoxyphenethyl)-4-(3-Phenylpropyl)-Piperazine Dihydro-Chloride on Inflammation after Stroke

(2012) Karsten Ruscher et al.   PLoS One

Sigma-1 receptor chaperone and brain-derived neurotrophic factor: Emerging links between cardiovascular disease and depression

(2012) Kenji Hashimoto   PROGRESS IN NEUROBIOLOGY

Targeting sigma-1 receptor signaling by endogenous ligands for cardioprotection

(2011) Md. Shenuarin Bhuiyan et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Targeting ligand-operated chaperone sigma-1 receptors in the treatment of neuropsychiatric disorders

(2011) Teruo Hayashi et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Neurosteroid Biosynthesis in the Brain of Amphibians

(2011) Hubert Vaudry et al.   Frontiers in Endocrinology

Microglial activation state exerts a biphasic influence on brain endothelial cell proliferation by regulating the balance of TNF and TGF-β1

(2010) Jennifer V Welser et al.   Journal of Neuroinflammation

Pharmacology of signaling induced by dopamine D1-like receptor activation

(2010) Ashiwel S. Undieh   PHARMACOLOGY & THERAPEUTICS

Does neuroinflammation fan the flame in neurodegenerative diseases?

(2009) Tamy C Frank-Cannon et al.   Molecular Neurodegeneration

The pharmacology of sigma-1 receptors

(2009) Tangui Maurice et al.   PHARMACOLOGY & THERAPEUTICS

Sigma receptors suppress multiple aspects of microglial activation

(2008) Aaron A. Hall et al.   GLIA

D5 Dopamine Receptors are Required for Dopaminergic Activation of Phospholipase C

(2008) A. Sahu et al.   MOLECULAR PHARMACOLOGY

Neuroprotective effects of atypical D1receptor agonist SKF83959 are mediated via D1receptor-dependent inhibition of glycogen synthase kinase-3β and a receptor-independent anti-oxidative action

(2007) Yang Yu et al.   JOURNAL OF NEUROCHEMISTRY