Evaluation of poly (ADP-ribose) polymerase inhibitor ABT-888 combined with radiotherapy and temozolomide in glioblastoma
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Title
Evaluation of poly (ADP-ribose) polymerase inhibitor ABT-888 combined with radiotherapy and temozolomide in glioblastoma
Authors
Keywords
Glioblastoma, PARP inhibition, ABT-888, Radiation, Temozolomide
Journal
Radiation Oncology
Volume 8, Issue 1, Pages 65
Publisher
Springer Nature
Online
2013-03-20
DOI
10.1186/1748-717x-8-65
References
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Related references
Note: Only part of the references are listed.- Overcoming Resistance of Glioblastoma to Conventional Cytotoxic Therapies by the Addition of PARP Inhibitors
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- Poly(ADP-Ribose) Polymerase Inhibition Synergizes with 5-Fluorodeoxyuridine but not 5-Fluorouracil in Ovarian Cancer Cells
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- (2011) S. Kummar et al. CANCER RESEARCH
- Poly(ADP-Ribose) Polymerase Inhibitor Induces Accelerated Senescence in Irradiated Breast Cancer Cells and Tumors
- (2010) E. V. Efimova et al. CANCER RESEARCH
- ABT-888 Confers Broad In vivo Activity in Combination with Temozolomide in Diverse Tumors
- (2009) J. P. Palma et al. CLINICAL CANCER RESEARCH
- Cytotoxic Effects of Temozolomide and Radiation are Additive- and Schedule-Dependent
- (2009) Anthony J. Chalmers et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Phase 0 Clinical Trial of the Poly (ADP-Ribose) Polymerase Inhibitor ABT-888 in Patients With Advanced Malignancies
- (2009) Shivaani Kummar et al. JOURNAL OF CLINICAL ONCOLOGY
- Poly(ADP-ribose) polymerase inhibitor ABT-888 potentiates the cytotoxic activity of temozolomide in leukemia cells: influence of mismatch repair status and O6-methylguanine-DNA methyltransferase activity
- (2009) T. M. Horton et al. MOLECULAR CANCER THERAPEUTICS
- Effective sensitization of temozolomide by ABT-888 is lost with development of temozolomide resistance in glioblastoma xenograft lines
- (2009) M. J. Clarke et al. MOLECULAR CANCER THERAPEUTICS
- In vitro and In vivo Radiosensitization Induced by the DNA Methylating Agent Temozolomide
- (2008) W. J. Kil et al. CLINICAL CANCER RESEARCH
- Replication-Dependent Radiosensitization of Human Glioma Cells by Inhibition of Poly(ADP-Ribose) Polymerase: Mechanisms and Therapeutic Potential
- (2008) Fiona A. Dungey et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Comprehensive genomic characterization defines human glioblastoma genes and core pathways
- (2008) Roger McLendon et al. NATURE
- A novel poly(ADP-ribose) polymerase inhibitor, ABT-888, radiosensitizes malignant human cell lines under hypoxia
- (2008) Stanley K. Liu et al. RADIOTHERAPY AND ONCOLOGY
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