Targeting cancer with sesterterpenoids: the new potential antitumor drugs

Phase II Study on Dose Escalating Schedule of Paclitaxel Concurrent with Radiotherapy in Treating Patients with Locally Advanced Non-small Cell Lung Cancer

(2014) Lin Cui et al.   Asian Pacific Journal of Cancer Prevention

Cytotoxic scalarane sesterterpenes from a Korean marine sponge Psammocinia sp.

(2013) Dongyup Hahn et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Heteronemin, a marine sponge terpenoid, targets TDP-43, a key factor in several neurodegenerative disorders

(2013) Chiara Cassiano et al.   CHEMICAL COMMUNICATIONS

Treatment with rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone is beneficial but toxic in very elderly patients with diffuse large B-cell lymphoma: a population-based cohort study on treatment, toxicity and outcome

(2013) Karin Boslooper et al.   LEUKEMIA & LYMPHOMA

Exploring the role of mitochondrial UQCRB in angiogenesis using small molecules

(2013) Hye Jin Jung et al.   Molecular BioSystems

Sesterterpenoids

(2013) Lishu Wang et al.   NATURAL PRODUCT REPORTS

A phase II window study of irinotecan (CPT-11) in high risk ewing sarcoma: A Euro-E.W.I.N.G. study

(2013) B. Morland et al.   PEDIATRIC BLOOD & CANCER

Ophiobolin A induces paraptosis-like cell death in human glioblastoma cells by decreasing BKCa channel activity

(2013) M Bury et al.   Cell Death & Disease

Terpenoids: natural products for cancer therapy

(2012) Min Huang et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Cytotoxic Sesterterpenoids from a Sponge Hippospongia sp.

(2012) Yu-Chia Chang et al.   Marine Drugs

Synthetic approaches toward sesterterpenoids

(2012) Daniel T. Hog et al.   NATURAL PRODUCT REPORTS

Cacospongionolide and Scalaradial, Two Marine Sesterterpenoids as Potent Apoptosis-Inducing Factors in Human Carcinoma Cell Lines

(2012) Daniela De Stefano et al.   PLoS One

Sesterterpenes from the Tropical SpongeCoscinodermasp.

(2011) Jaemin Bae et al.   JOURNAL OF NATURAL PRODUCTS

Cytotoxic C21and C22Terpenoid-Derived Metabolites from the SpongeIrciniasp.

(2011) Jui-Hsin Su et al.   JOURNAL OF NATURAL PRODUCTS

Inhibition of tumor progression by naturally occurring terpenoids

(2011) Girija Kuttan et al.   PHARMACEUTICAL BIOLOGY

Globostelletins A–I, cytotoxic isomalabaricane derivatives from the marine sponge Rhabdastrella globostellata

(2010) Jin Li et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Hypoxia-Selective Growth Inhibition of Cancer Cells by Furospinosulin-1, a Furanosesterterpene Isolated from an Indonesian Marine Sponge

(2010) Masayoshi Arai et al.   ChemMedChem

Targeting Apoptosis Pathway with Natural Terpenoids: Implications for Treatment of Breast and Prostate Cancer

(2010) Huanjie Yang et al.   CURRENT DRUG TARGETS

Terpestacin Inhibits Tumor Angiogenesis by Targeting UQCRB of Mitochondrial Complex III and Suppressing Hypoxia-induced Reactive Oxygen Species Production and Cellular Oxygen Sensing

(2010) Hye Jin Jung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bioactive Sesterterpenes and Triterpenes from Marine Sponges: Occurrence and Pharmacological Significance

(2010) Sherif S. Ebada et al.   Marine Drugs

Rhabdastrellic Acid-A Induced Autophagy-Associated Cell Death through Blocking Akt Pathway in Human Cancer Cells

(2010) Dan-Dan Li et al.   PLoS One

Heteronemin, a spongean sesterterpene, inhibits TNFα-induced NF-κB activation through proteasome inhibition and induces apoptotic cell death

(2009) Marc Schumacher et al.   BIOCHEMICAL PHARMACOLOGY

Monoterpene and sesquiterpene synthases and the origin of terpene skeletal diversity in plants

(2009) Jörg Degenhardt et al.   PHYTOCHEMISTRY

Terpenoids and breast cancer chemoprevention

(2008) Thangaiyan Rabi et al.   BREAST CANCER RESEARCH AND TREATMENT

Aplysinoplides A−C, Cytotoxic Sesterterpenes from the Marine SpongeAplysinopsis digitata

(2008) Reiko Ueoka et al.   JOURNAL OF NATURAL PRODUCTS

The Inhibitory Action of Kohamaic Acid A Derivatives on Mammalian DNA Polymerase β

(2008) Yoshiyuki Mizushina et al.   MOLECULES