Genomic impact of cigarette smoke, with application to three smoking-related diseases

Coordinated changes in AHRR methylation in lymphoblasts and pulmonary macrophages from smokers

(2012) Martha M. Monick et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

The Relationship between Lung Inflammation and Cardiovascular Disease

(2012) Stephan Van Eeden et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Assessment of network perturbation amplitudes by applying high-throughput data to causal biological networks

(2012) Florian Martin et al.   BMC Systems Biology

Cancer epigenomics: beyond genomics

(2012) Juan Sandoval et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Variable DNA Methylation Is Associated with Chronic Obstructive Pulmonary Disease and Lung Function

(2011) Weiliang Qiu et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Landscape of Next-Generation Sequencing Technologies

(2011) Thomas P. Niedringhaus et al.   ANALYTICAL CHEMISTRY

Characterizing the Impact of Smoking and Lung Cancer on the Airway Transcriptome Using RNA-Seq

(2011) J. Beane et al.   Cancer Prevention Research

Role of histone deacetylases in vascular cell homeostasis and arteriosclerosis

(2011) B. Zhou et al.   CARDIOVASCULAR RESEARCH

Genomic Profiles Specific to Patient Ethnicity in Lung Adenocarcinoma

(2011) P. Broet et al.   CLINICAL CANCER RESEARCH

An Epigenetic Marker Panel for Detection of Lung Cancer Using Cell-Free Serum DNA

(2011) S. Begum et al.   CLINICAL CANCER RESEARCH

Lung cancer and its association with chronic obstructive pulmonary disease: update on nexus of epigenetics

(2011) Isaac K Sundar et al.   CURRENT OPINION IN PULMONARY MEDICINE

A network-based approach to quantifying the impact of biologically active substances

(2011) Julia Hoeng et al.   DRUG DISCOVERY TODAY

Ketamine may exert antidepressant effects via mediating the kynurenine pathway

(2011) Chun Yang et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Common pathogenic mechanisms and pathways in the development of COPD and lung cancer

(2011) Ian A Yang et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Environmental chemical exposures and human epigenetics

(2011) Lifang Hou et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Epigenetics and environmental exposures

(2011) Richard A Stein   JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH

DNA Methylation Changes in Atypical Adenomatous Hyperplasia, Adenocarcinoma In Situ, and Lung Adenocarcinoma

(2011) Suhaida A. Selamat et al.   PLoS One

Cigarette smoking increases copy number alterations in nonsmall-cell lung cancer

(2011) Y.-T. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA methylation profile during multistage progression of pulmonary adenocarcinomas

(2011) Jin-Haeng Chung et al.   VIRCHOWS ARCHIV

Protein kinase CK2-mediated phosphorylation of HDAC2 regulates co-repressor formation, deacetylase activity and acetylation of HDAC2 by cigarette smoke and aldehydes

(2010) David Adenuga et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Introduction into the analysis of high-throughput-sequencing based epigenome data

(2010) M. Huss   BRIEFINGS IN BIOINFORMATICS

Molecular Analysis of Plasma DNA for the Early Detection of Lung Cancer by Quantitative Methylation-Specific PCR

(2010) K. L. Ostrow et al.   CLINICAL CANCER RESEARCH

Next-generation sequencing: emerging lessons on the origins of human cancer

(2010) Gerd P Pfeifer et al.   CURRENT OPINION IN ONCOLOGY

A further review of inhalation studies with cigarette smoke and lung cancer in experimental animals, including transgenic mice

(2010) C.R.E. Coggins   INHALATION TOXICOLOGY

Dose effect of cigarette smoking on frequency and spectrum of epidermal growth factor receptor gene mutations in Korean patients with non-small cell lung cancer

(2010) Young Joo Lee et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Epigenetics in atherosclerosis and inflammation

(2010) Rutger J. Wierda et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The tobacco-specific carcinogen NNK induces DNA methyltransferase 1 accumulation and tumor suppressor gene hypermethylation in mice and lung cancer patients

(2010) Ruo-Kai Lin et al.   JOURNAL OF CLINICAL INVESTIGATION

Mutagenicity of 11 cigarette smoke condensates in two versions of the mouse lymphoma assay

(2010) X. Guo et al.   MUTAGENESIS

Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications

(2010) R Alan Harris et al.   NATURE BIOTECHNOLOGY

Quantitative comparison of genome-wide DNA methylation mapping technologies

(2010) Christoph Bock et al.   NATURE BIOTECHNOLOGY

Epigenomic alterations and gene expression profiles in respiratory epithelia exposed to cigarette smoke condensate

(2010) F Liu et al.   ONCOGENE

DNA Methylation as a Biomarker for Cardiovascular Disease Risk

(2010) Myungjin Kim et al.   PLoS One

The DNA Methylome of Human Peripheral Blood Mononuclear Cells

(2010) Yingrui Li et al.   PLOS BIOLOGY

Lung Cancer Stem Cell: New Insights on Experimental Models and Preclinical Data

(2010) Caroline Rivera et al.   Journal of Oncology

Evaluation of In vitro Assays for Assessing the Toxicity of Cigarette Smoke and Smokeless Tobacco

(2009) M. D. Johnson et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

COPD as a Disease of Accelerated Lung Aging

(2009) Kazuhiro Ito et al.   CHEST

Pulmonary preneoplasia - sequential molecular carcinogenetic events

(2009) Sylvie Lantuéjoul et al.   HISTOPATHOLOGY

Hypoxic Repression of Endothelial Nitric-oxide Synthase Transcription Is Coupled with Eviction of Promoter Histones

(2009) Jason E. Fish et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multifocal Lung Cancers--Clonality vs Field Cancerization and Does It Matter?

(2009) A. F. Gazdar et al.   JNCI-Journal of the National Cancer Institute

Clinicopathological predictors of EGFR/KRAS mutational status in primary lung adenocarcinomas

(2009) Sanja Dacic et al.   MODERN PATHOLOGY

Relationship between TP53 tumour suppressor gene mutations and smoking-related bulky DNA adducts in a lung cancer study population from Hungary

(2009) Lívia Anna et al.   MUTAGENESIS

A small-cell lung cancer genome with complex signatures of tobacco exposure

(2009) Erin D. Pleasance et al.   NATURE

Smoking Induces Long-Lasting Effects through a Monoamine-Oxidase Epigenetic Regulation

(2009) Jean-Marie Launay et al.   PLoS One

Genetic dissection of histone deacetylase requirement in tumor cells

(2009) M. Haberland et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Toxicology for the 21st Century—Mapping the Road Ahead

(2009) Thomas Hartung   TOXICOLOGICAL SCIENCES

Inhalation of cigarette smoke induces regions of altered DNA methylation (RAMs) in SENCAR mouse lung

(2009) Jennifer M. Phillips et al.   TOXICOLOGY

SIRT1, an Antiinflammatory and Antiaging Protein, Is Decreased in Lungs of Patients with Chronic Obstructive Pulmonary Disease

(2008) Saravanan Rajendrasozhan et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

IKKα Causes Chromatin Modification on Pro-Inflammatory Genes by Cigarette Smoke in Mouse Lung

(2008) Se-Ran Yang et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Histone Deacetylase 2 Is Phosphorylated, Ubiquitinated, and Degraded by Cigarette Smoke

(2008) David Adenuga et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

A high-throughput and sensitive method to measure Global DNA Methylation: Application in Lung Cancer

(2008) Anthony Anisowicz et al.   BMC CANCER

DNA Methylation in Tumor and Matched Normal Tissues from Non-Small Cell Lung Cancer Patients

(2008) Q. Feng et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Oral Epithelium as a Surrogate Tissue for Assessing Smoking-Induced Molecular Alterations in the Lungs

(2008) Manisha Bhutani et al.   Cancer Prevention Research

The Field of Tissue Injury in the Lung and Airway

(2008) K. Steiling et al.   Cancer Prevention Research

Carcinogen-Induced Gene Promoter Hypermethylation Is Mediated by DNMT1 and Causal for Transformation of Immortalized Bronchial Epithelial Cells

(2008) Leah A. Damiani et al.   CANCER RESEARCH

Molecular Alterations in Spontaneous Sputum of Cancer-Free Heavy Smokers: Results from a Large Screening Program

(2008) E. Baryshnikova et al.   CLINICAL CANCER RESEARCH

Promoter Hypermethylation of Hallmark Cancer Genes in Atypical Adenomatous Hyperplasia of the Lung

(2008) J. D.F. Licchesi et al.   CLINICAL CANCER RESEARCH

Detection of Altered Global DNA Methylation in Coronary Artery Disease Patients

(2008) Priyanka Sharma et al.   DNA AND CELL BIOLOGY

Environmental epigenomics in human health and disease

(2008) Dana C. Dolinoy et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Requirement of HDAC6 for Transforming Growth Factor-β1-induced Epithelial-Mesenchymal Transition

(2008) Bin Shan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Somatic mutations affect key pathways in lung adenocarcinoma

(2008) Li Ding et al.   NATURE

Lung Cancer

(2008) Roy S. Herbst et al.   NEW ENGLAND JOURNAL OF MEDICINE

Egr-1 Regulates Autophagy in Cigarette Smoke-Induced Chronic Obstructive Pulmonary Disease

(2008) Zhi-Hua Chen et al.   PLoS One

Systems Biology and Mode of Action Based Risk Assessment

(2008) Stephen W. Edwards et al.   TOXICOLOGICAL SCIENCES

Genotoxicity of 10 cigarette smoke condensates in four test systems: Comparisons between assays and condensates

(2007) David M. DeMarini et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS