Article
Environmental Sciences
Gerardo Heredia-Garcia, Leobardo Manuel Gomez-Olivan, Gustavo Axel Elizalde-Velazquez, Jesus Daniel Cardoso-Vera, Jose Manuel Orozco-Hernandez, Karina Elisa Rosales-Perez, Sandra Garcia-Medina, Hariz Islas-Flores, Marcela Galar-Martinez, Octavio Dublan-Garcia
Summary: This study assessed the effects of Bisphenol A on zebrafish embryos and found that it caused developmental malformations and altered oxidative status and gene expression.
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
(2022)
Review
Public, Environmental & Occupational Health
Ewelina Czubacka, Slawomir Czerczak, Malgorzata Miroslawa Kupczewska-Dobecka
Summary: DBP as an endocrine disruptor has significant negative effects on reproduction in animals, including reduced fertility, decreased sperm count and motility, and developmental abnormalities.
INTERNATIONAL JOURNAL OF OCCUPATIONAL MEDICINE AND ENVIRONMENTAL HEALTH
(2021)
Article
Engineering, Environmental
Haobo Wang, Zhongyu Wang, Jingwen Chen, Wenjia Liu
Summary: In this study, graph attention networks (GATs) were introduced to construct models for screening PBT chemicals, and an AD characterization termed ADFP-AC was proposed. The results showed that the GAT model outperformed previous models and exhibited interpretability.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Environmental Sciences
Mason D. King, John E. Elliott, Vicki Marlatt, Doug Crump, Ifeoluwa Idowu, Sarah J. Wallace, Gregg T. Tomy, Tony D. Williams
Summary: This study found that dilbit can cross the eggshell and be absorbed by embryos, indicating rapid metabolism of polycyclic aromatic compounds and a nonmonotonic response in Cyp1a4. Despite evidence of exposure in cormorant, no detectable effects were found on survival, deformity, and physiological endpoints, suggesting that in ovo dilbit exposure may be less toxic than conventional crude oils.
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
(2022)
Article
Engineering, Environmental
Zhongyu Wang, Jingwen Chen, Huixiao Hong
Summary: This study developed 30 QSAR models based on PPAR gamma binding affinity data, using molecular fingerprints, two-dimensional descriptors, and five machine learning algorithms. Local discontinuity scores were positively correlated with prediction errors of the models, and innovative ADs outperformed traditional ones. The curated data sets and models can be used to evaluate adverse effects of chemicals.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2021)
Article
Chemistry, Medicinal
Olga Konyaeva, Nataliya Kulbachevskaya, Vera Chaley, Nadezhda Ermakova, Pavel Varaksa, Anna Lantsova, Lyudmila Nikolaeva, Olga Orlova, Yuliya Rodionova, Natalia Bunyatyan
Summary: The study on Lipophtalocyan in rats showed that the drug has negative effects on male and female reproductive function, affecting fertility index, early embryonic death, but without teratogenic effects.
Article
Biochemistry & Molecular Biology
S. Zachary Swartz, Tzer Han Tan, Margherita Perillo, Nikta Fakhri, Gary M. Wessel, Athula H. Wikramanayake, Iain M. Cheeseman
Summary: In meiotic oocytes of the sea star Patifia miniata, the distribution dynamics of the Disheveled protein are regulated by meiotic cell cycle progression and influenced by association with Lamp1+ endosomes and pre-localized Frizzled receptors within the oocyte cortex.
Review
Pharmacology & Pharmacy
Alan M. Hoberman, Kazushige Maki, Fumito Mikashima, Misaki Naota, Ronald L. Wange, Janice A. Lansita, Shawna L. Weis
Summary: Embryofetal toxicity studies are important for supporting clinical trials and labeling of pharmaceutical products. Nonhuman primate models are commonly used to evaluate embryofetal toxicity, especially for biopharmaceuticals. However, conducting these studies has become increasingly challenging due to limited facilities and a shortage of sexually mature monkeys.
INTERNATIONAL JOURNAL OF TOXICOLOGY
(2023)
Article
Toxicology
Christian Riebeling, Kristin Fischer, Andreas Luch, Andrea E. M. Seiler
JOURNAL OF TOXICOLOGICAL SCIENCES
(2015)
Article
Nanoscience & Nanotechnology
Christian Riebeling, Andreas Luch, Mario Enrico Goetz
Article
Toxicology
Marc D. Driessen, Sarah Mues, Antje Vennemann, Bryan Hellack, Anne Bannuscher, Vishalini Vimalakanthan, Christian Riebeling, Rainer Ossig, Martin Wiemann, Juergen Schnekenburger, Thomas A. J. Kuhlbusch, Bernhard Renard, Andreas Luch, Andrea Haase
PARTICLE AND FIBRE TOXICOLOGY
(2015)
Review
Toxicology
Andrea Seiler, Michael Oelgeschlaeger, Manfred Liebsch, Ralph Pirow, Christian Riebeling, Tewes Tralau, Andreas Luch
ARCHIVES OF TOXICOLOGY
(2011)
Editorial Material
Toxicology
Manfred Liebsch, Barbara Grune, Andrea Seiler, Daniel Butzke, Michael Oelgeschlaeger, Ralph Pirow, Sarah Adler, Christian Riebeling, Andreas Luch
ARCHIVES OF TOXICOLOGY
(2011)
Article
Biochemistry & Molecular Biology
Christian Riebeling, Sylvain Bourgoin, Dennis Shields
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
(2008)
Review
Biochemistry & Molecular Biology
Christian Riebeling, Andrew J. Morris, Dennis Shields
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
(2009)
Article
Environmental Sciences
Tewes Tralau, Christian Riebeling, Ralph Pirow, Michael Oelgeschlaeger, Andrea Seiler, Manfred Liebsch, Andreas Luch
ENVIRONMENTAL HEALTH PERSPECTIVES
(2012)
Article
Neurosciences
Anke Visan, Katrin Hayess, Dana Sittner, Elena E. Pohl, Christian Riebeling, Birgitta Slawik, Konrad Gulich, Michael Oelgeschlaeger, Andreas Luch, Andrea E. M. Seiler
Article
Toxicology
Christian Riebeling, Ralph Pirow, Klaus Becker, Roland Buesen, Daniel Eikel, Johanna Kaltenhaeuser, Frauke Meyer, Heinz Nau, Birgitta Slawik, Anke Visan, Jutta Volland, Horst Spielmann, Andreas Luch, Andrea Seiler
TOXICOLOGICAL SCIENCES
(2011)
Article
Pharmacology & Pharmacy
Katrin Hayess, Christian Riebeling, Ralph Pirow, Matthias Steinfath, Dana Sittner, Birgitta Slawik, Andreas Luch, Andrea E. M. Seiler
Article
Toxicology
Christian Riebeling, Katharina Schlechter, Roland Buesen, Horst Spielmann, Andreas Luch, Andrea Seiler
TOXICOLOGY IN VITRO
(2011)
Article
Oncology
AM Forsea, C Müller, C Riebeling, CE Orfanos, CC Geilen
BRITISH JOURNAL OF CANCER
(2004)
Article
Biochemistry & Molecular Biology
C Riebeling, JC Allegood, E Wang, AH Merrill, AH Futerman
JOURNAL OF BIOLOGICAL CHEMISTRY
(2003)