Structural and functional insights into human vitamin K epoxide reductase and vitamin K epoxide reductase-like1

The Discovery of Vitamin K and Its Clinical Applications

(2012) Guylaine Ferland   ANNALS OF NUTRITION AND METABOLISM

Vitamin K, an emerging nutrient in brain function

(2012) Guylaine Ferland   BIOFACTORS

Warfarin Pharmacogenetics

(2012) Julie A. Johnson   CIRCULATION

Disulfide bond formation network in the three biological kingdoms, bacteria, fungi and mammals

(2012) Yoshimi Sato et al.   FEBS Journal

Protein disulfide isomerase in redox cell signaling and homeostasis

(2012) Francisco R.M. Laurindo et al.   FREE RADICAL BIOLOGY AND MEDICINE

Human Vitamin K Epoxide Reductase and Its Bacterial Homologue Have Different Membrane Topologies and Reaction Mechanisms

(2012) Jian-Ke Tie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipid-dependent Generation of Dual Topology for a Membrane Protein

(2012) Mikhail Bogdanov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

VKORC1mutations detected in patients resistant to vitamin K antagonists are not all associated with a resistant VKOR activity

(2012) A. HODROGE et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Vitamin K2 Is a Mitochondrial Electron Carrier That Rescues Pink1 Deficiency

(2012) M. Vos et al.   SCIENCE

Warfarin Pharmacogenetics: Does More Accurate Dosing Benefit Patients?

(2012) Charles Eby   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Vitamin K and the Nervous System: An Overview of its Actions

(2012) Guylaine Ferland   Advances in Nutrition

Membrane Protein Insertion at the Endoplasmic Reticulum

(2011) Sichen Shao et al.   Annual Review of Cell and Developmental Biology

Mycobacterium tuberculosis Vitamin K Epoxide Reductase Homologue Supports Vitamin K–Dependent Carboxylation in Mammalian Cells

(2011) Jian-Ke Tie et al.   ANTIOXIDANTS & REDOX SIGNALING

Functional study of the vitamin K cycle in mammalian cells

(2011) J.-K. Tie et al.   BLOOD

Guideline-Discordant Periprocedural Interruptions in Warfarin Therapy

(2011) Lesli E. Skolarus et al.  

The Bladder Tumor Suppressor Protein TERE1 (UBIAD1)Modulates Cell Cholesterol: Implications for Tumor Progression

(2011) William J. Fredericks et al.   DNA AND CELL BIOLOGY

Human Vitamin K 2,3-Epoxide Reductase Complex Subunit 1-like 1 (VKORC1L1) Mediates Vitamin K-dependent Intracellular Antioxidant Function

(2011) Philipp Westhofen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A hetero-dimer model for concerted action of vitamin K carboxylase and vitamin K reductase in vitamin K cycle

(2011) Sangwook Wu et al.   JOURNAL OF THEORETICAL BIOLOGY

Glutathione in Cancer Cell Death

(2011) Angel L. Ortega et al.   Cancers

Dietary vitamin K intake in relation to cancer incidence and mortality: results from the Heidelberg cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC-Heidelberg)

(2010) Katharina Nimptsch et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Conformational Analysis of Membrane Proteins in Phospholipid Bilayer Nanodiscs by Hydrogen Exchange Mass Spectrometry

(2010) Christine M. Hebling et al.   ANALYTICAL CHEMISTRY

Membrane Topology and Mutational Analysis of Mycobacterium tuberculosis VKOR, a Protein Involved in Disulfide Bond Formation and a Homologue of Human Vitamin K Epoxide Reductase

(2010) Xiaoyun Wang et al.   ANTIOXIDANTS & REDOX SIGNALING

A Polymorphism in the VKORC1 Regulator Calumenin Predicts Higher Warfarin Dose Requirements in African Americans

(2010) D Voora et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Proteins that switch folds

(2010) Philip N Bryan et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Novel Thioredoxin-related Transmembrane Protein TMX4 Has Reductase Activity

(2010) Yoshimi Sugiura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel Insight into the Mechanism of the Vitamin K Oxidoreductase (VKOR)

(2010) Mark A. Rishavy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of UBIAD1 as a novel human menaquinone-4 biosynthetic enzyme

(2010) Kimie Nakagawa et al.   NATURE

Structure of a bacterial homologue of vitamin K epoxide reductase

(2010) Weikai Li et al.   NATURE

Vitamin K epoxide reductase prefers ER membrane-anchored thioredoxin-like redox partners

(2010) S. Schulman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Control of Membrane Protein Topology by a Single C-Terminal Residue

(2010) S. Seppala et al.   SCIENCE

Pharmacogenetics of Warfarin

(2009) Farhad Kamali et al.   Annual Review of Medicine

Protein Disulfide Isomerase: A Critical Evaluation of Its Function in Disulfide Bond Formation

(2009) Feras Hatahet et al.   ANTIOXIDANTS & REDOX SIGNALING

Anticoagulant Rodenticides in Three Owl Species from Western Canada, 1988–2003

(2009) Courtney A. Albert et al.   ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY

A di-arginine motif contributes to the ER localization of the type I transmembrane ER oxidoreductase TMX4

(2009) Doris Roth et al.   BIOCHEMICAL JOURNAL

Novel mutations in the VKORC1 gene of wild rats and mice - a response to 50 years of selection pressure by warfarin?

(2009) Simone Rost et al.   BMC GENETICS

Inhibition of bacterial disulfide bond formation by the anticoagulant warfarin

(2009) R. J. Dutton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacterial species exhibit diversity in their mechanisms and capacity for protein disulfide bond formation

(2008) R. J. Dutton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

No association between vitamin K epoxide reductase complex subunit 1-like 1 (VKORC1L1) and the variability of warfarin dose requirement in a Japanese patient population

(2007) Tong Yin et al.   THROMBOSIS RESEARCH