Disulfide bond formation network in the three biological kingdoms, bacteria, fungi and mammals

Structure, Mechanism, and Evolution of Ero1 Family Enzymes

(2011) Kazutaka Araki et al.   ANTIOXIDANTS & REDOX SIGNALING

The endoplasmic reticulum sulfhydryl oxidase Ero1β drives efficient oxidative protein folding with loose regulation

(2011) Lei Wang et al.   BIOCHEMICAL JOURNAL

Structural insights into the peroxidase activity and inactivation of human peroxiredoxin 4

(2011) Xi Wang et al.   BIOCHEMICAL JOURNAL

Molecular Bases of Cyclic and Specific Disulfide Interchange between Human ERO1α Protein and Protein-disulfide Isomerase (PDI)

(2011) Shoji Masui et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure of Reduced and of Oxidized Peroxiredoxin IV Enzyme Reveals a Stable Oxidized Decamer and a Non-disulfide-bonded Intermediate in the Catalytic Cycle

(2011) Zhenbo Cao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Vitamin K 2,3-Epoxide Reductase Complex Subunit 1-like 1 (VKORC1L1) Mediates Vitamin K-dependent Intracellular Antioxidant Function

(2011) Philipp Westhofen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Two Endoplasmic Reticulum PDI Peroxidases Increase the Efficiency of the Use of Peroxide during Disulfide Bond Formation

(2011) Van Dat Nguyen et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural Basis of an ERAD Pathway Mediated by the ER-Resident Protein Disulfide Reductase ERdj5

(2011) Masatoshi Hagiwara et al.   MOLECULAR CELL

Multiple ways to make disulfides

(2011) Neil J. Bulleid et al.   TRENDS IN BIOCHEMICAL SCIENCES

Molecular Mechanisms Regulating Oxidative Activity of the Ero1 Family in the Endoplasmic Reticulum

(2010) Timothy J. Tavender et al.   ANTIOXIDANTS & REDOX SIGNALING

Oxidative Protein Folding and the Quiescin–Sulfhydryl Oxidase Family of Flavoproteins

(2010) Vamsi K. Kodali et al.   ANTIOXIDANTS & REDOX SIGNALING

Recycling of peroxiredoxin IV provides a novel pathway for disulphide formation in the endoplasmic reticulum

(2010) Timothy J Tavender et al.   EMBO JOURNAL

Crystal structures of human Ero1α reveal the mechanisms of regulated and targeted oxidation of PDI

(2010) Kenji Inaba et al.   EMBO JOURNAL

MBSJ MCC Young Scientist Award 2009
REVIEW: Structural basis of protein disulfide bond generation in the cell

(2010) Kenji Inaba   GENES TO CELLS

Novel Insight into the Mechanism of the Vitamin K Oxidoreductase (VKOR)

(2010) Mark A. Rishavy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxidative Activity of Yeast Ero1p on Protein Disulfide Isomerase and Related Oxidoreductases of the Endoplasmic Reticulum

(2010) Elvira Vitu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ERO1-β, a pancreas-specific disulfide oxidase, promotes insulin biogenesis and glucose homeostasis

(2010) Ester Zito et al.   JOURNAL OF CELL BIOLOGY

Functional Relationship between Protein Disulfide Isomerase Family Members during the Oxidative Folding of Human Secretory Proteins

(2010) Lori A. Rutkevich et al.   MOLECULAR BIOLOGY OF THE CELL

Oxidative Protein Folding by an Endoplasmic Reticulum-Localized Peroxiredoxin

(2010) Ester Zito et al.   MOLECULAR CELL

Structure of a bacterial homologue of vitamin K epoxide reductase

(2010) Weikai Li et al.   NATURE

Vitamin K epoxide reductase prefers ER membrane-anchored thioredoxin-like redox partners

(2010) S. Schulman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Steps in reductive activation of the disulfide-generating enzyme Ero1p

(2010) Nimrod Heldman et al.   PROTEIN SCIENCE

ERp46 is reduced by high glucose and regulates insulin content in pancreatic β-cells

(2009) Avra Alberti et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Protein Disulfide Isomerase: A Critical Evaluation of Its Function in Disulfide Bond Formation

(2009) Feras Hatahet et al.   ANTIOXIDANTS & REDOX SIGNALING

Dynamic nature of disulphide bond formation catalysts revealed by crystal structures of DsbB

(2009) Kenji Inaba et al.   EMBO JOURNAL

Disulfide Bond Formation System in Escherichia coli

(2009) K. Inaba   JOURNAL OF BIOCHEMISTRY

Structure and Functional Properties ofBacillus subtilisEndospore Biogenesis Factor StoA

(2009) Allister Crow et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein disulphide isomerase family members show distinct substrate specificity: P5 is targeted to BiP client proteins

(2009) C. E. Jessop et al.   JOURNAL OF CELL SCIENCE

An Unfolded CH1 Domain Controls the Assembly and Secretion of IgG Antibodies

(2009) Matthias J. Feige et al.   MOLECULAR CELL

Human Quiescin-Sulfhydryl Oxidase, QSOX1: Probing Internal Redox Steps by Mutagenesis†

(2008) Erin J. Heckler et al.   BIOCHEMISTRY

A novel disulphide switch mechanism in Ero1α balances ER oxidation in human cells

(2008) Christian Appenzeller-Herzog et al.   EMBO JOURNAL

Low reduction potential of Ero1α regulatory disulphides ensures tight control of substrate oxidation

(2008) Karl M Baker et al.   EMBO JOURNAL

Reconstitution of Human Ero1-Lα/Protein-Disulfide Isomerase Oxidative Folding Pathwayin Vitro

(2008) Lei Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Substrate Specificity of the Oxidoreductase ERp57 Is Determined Primarily by Its Interaction with Calnexin and Calreticulin

(2008) Catherine E. Jessop et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Catalytic Activity of Protein-disulfide Isomerase Requires a Conformationally Flexible Molecule

(2008) Geng Tian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bacterial species exhibit diversity in their mechanisms and capacity for protein disulfide bond formation

(2008) R. J. Dutton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ERdj5 Is Required as a Disulfide Reductase for Degradation of Misfolded Proteins in the ER

(2008) R. Ushioda et al.   SCIENCE

The Machinery for Oxidative Protein Folding in Thermophiles

(2007) Emilia Pedone et al.   ANTIOXIDANTS & REDOX SIGNALING

The Erv family of sulfhydryl oxidases

(2007) Deborah Fass   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Ero1 and redox homeostasis in the endoplasmic reticulum

(2007) Carolyn S. Sevier et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH