Survivin: A target from brain cancer to neurodegenerative disease

Recent Advances in Nanoneurology for Drug Delivery to the Brain

(2012) Jagat Kanwar et al.   Current Nanoscience

Survivin(g) phosphorylation? Survivin phosphorylation, mitosis and apoptosis

(2011) Patrick Eyers   CELL CYCLE

Role of Signal Transducer and Activator of Transcription 3 in Neuronal Survival and Regeneration

(2011) Suzan Dziennis et al.   REVIEWS IN THE NEUROSCIENCES

A survivin double point mutant has potent inhibitory effect on the growth of hepatocellular cancer cells

(2010) Rui Zhang et al.   CANCER BIOLOGY & THERAPY

Antitumor cytotoxic T-cell response induced by a survivin peptide mimic

(2010) Michael J. Ciesielski et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

YM155: A Small Molecule Survivin Suppressant with Potent Antitumor Effect in Human Breast Cancer Models.

(2010) A. Kita et al.   CANCER RESEARCH

Prevention of ischemic brain injury by treatment with the membrane penetrating apoptosis inhibitor, TAT-BH4

(2010) Sandra Donnini et al.   CELL CYCLE

Recent Advances in Anti-Survivin Treatments for Cancer

(2010) R. Kanwar et al.   CURRENT MEDICINAL CHEMISTRY

Necroptosis as an alternative form of programmed cell death

(2010) Dana E Christofferson et al.   CURRENT OPINION IN CELL BIOLOGY

Mechanisms that regulate the number of neurons during mouse neocortical development

(2010) Takaki Miyata et al.   CURRENT OPINION IN NEUROBIOLOGY

Proliferative and protective effects of SurR9-C84A on differentiated neural cells

(2010) Sara Baratchi et al.   JOURNAL OF NEUROIMMUNOLOGY

Targeting Hsp90 with small molecule inhibitors induces the over-expression of the anti-apoptotic molecule, survivin, in human A549, HONE-1 and HT-29 cancer cells

(2010) Chun Hei Antonio Cheung et al.   Molecular Cancer

Neuroprotective Effects of Caspase-3 Inhibition on Functional Recovery and Tissue Sparing After Acute Spinal Cord Injury

(2010) Bruce A. Citron et al.   SPINE

Cell cycle control of mammalian neural stem cells: putting a speed limit on G1

(2010) Paolo Salomoni et al.   TRENDS IN CELL BIOLOGY

From Birth Till Death: Neurogenesis, Cell Cycle, and Neurodegeneration

(2009) Ozlem Demir et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

The Role of Mitochondria in Apoptosis

(2009) Chunxin Wang et al.   Annual Review of Genetics

3,4-Dihydropyrimido(1,2-a)indol-10(2H)-ones as potent non-peptidic inhibitors of caspase-3

(2009) Lisa M. Havran et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Role of the 2 zebrafish survivin genes in vasculo-angiogenesis, neurogenesis, cardiogenesis and hematopoiesis

(2009) Mieke Delvaeye et al.   BMC DEVELOPMENTAL BIOLOGY

Caspase substrates and neurodegenerative diseases

(2009) Natasa Bulat et al.   BRAIN RESEARCH BULLETIN

Phase I clinical study of anti-apoptosis protein survivin-derived peptide vaccination for patients with advanced or recurrent urothelial cancer

(2009) Ichiya Honma et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Survivin: A new target for anti-cancer therapy

(2009) Bríd M. Ryan et al.   CANCER TREATMENT REVIEWS

Structural Basis for Self-Renewal of Neural Progenitors in Cortical Neurogenesis

(2009) G. Shioi et al.   CEREBRAL CORTEX

Phase I Study of YM155, a Novel Survivin Suppressant, in Patients with Advanced Solid Tumors

(2009) T. Satoh et al.   CLINICAL CANCER RESEARCH

Recent Advances on the Roles of NO in Cancer and Chronic Inflammatory Disorders

(2009) Jagat Kanwar et al.   CURRENT MEDICINAL CHEMISTRY

17 AAG for HSP90 Inhibition in Cancer – From Bench to Bedside

(2009) Saad Usmani et al.   CURRENT MOLECULAR MEDICINE

Promises of Nanotechnology for Drug Delivery to Brain in Neurodegenerative Diseases

(2009) Sara Baratchi et al.   Current Nanoscience

Characterization of Human Organic Cation Transporter 1 (OCT1/SLC22A1)- and OCT2 (SLC22A2)-Mediated Transport of 1-(2-Methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)- 4,9-dihydro-1H-naphtho[2,3-d]imidazolium Bromide (YM155 Monobromide), a Novel Small Molecule Survivin Suppressant

(2009) T. Minematsu et al.   DRUG METABOLISM AND DISPOSITION

Overcoming inhibition in the spindle checkpoint

(2009) V. Vanoosthuyse et al.   GENES & DEVELOPMENT

Increased expression of inhibitor of apoptosis proteins, survivin and XIAP, in non-small cell lung carcinoma

(2009) Krepela   INTERNATIONAL JOURNAL OF ONCOLOGY

Bcl-xLincreases mitochondrial fission, fusion, and biomass in neurons

(2009) Sarah B. Berman et al.   JOURNAL OF CELL BIOLOGY

Regulation of cell migration and morphogenesis by Abl-family kinases: emerging mechanisms and physiological contexts

(2009) W. D. Bradley et al.   JOURNAL OF CELL SCIENCE

Apoptotic Mechanisms in the Immature Brain: Involvement of Mitochondria

(2009) Henrik Hagberg et al.   JOURNAL OF CHILD NEUROLOGY

Phase II Study of Flavopiridol in Relapsed Chronic Lymphocytic Leukemia Demonstrating High Response Rates in Genetically High-Risk Disease

(2009) Thomas S. Lin et al.   JOURNAL OF CLINICAL ONCOLOGY

Multicenter Phase II Trial of YM155, a Small-Molecule Suppressor of Survivin, in Patients With Advanced, Refractory, Non–Small-Cell Lung Cancer

(2009) Giuseppe Giaccone et al.   JOURNAL OF CLINICAL ONCOLOGY

Overexpression of Bcl-XLin human neural stem cells promotes graft survival and functional recovery following transplantation in spinal cord injury

(2009) Seung I. Lee et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Oxysterols and mechanisms of apoptotic signaling: implications in the pathology of degenerative diseases☆

(2009) Sinéad Lordan et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Efficient Chromosome Biorientation and the Tension Checkpoint in Saccharomyces cerevisiae both Require Bir1

(2009) V. Makrantoni et al.   MOLECULAR AND CELLULAR BIOLOGY

A Tcf4-GFP reporter mouse model for monitoring effects ofApcmutations during intestinal tumorigenesis

(2009) Bruce Boman et al.   MOLECULAR CARCINOGENESIS

Calcium signaling in neurodegeneration

(2009) Philippe Marambaud et al.   Molecular Neurodegeneration

DNA methylation inhibits p53-mediated survivin repression

(2009) N H Nabilsi et al.   ONCOGENE

Mitochondrial function as a determinant of life span

(2009) Ian R. Lanza et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Differential gene expression and alternative splicing of survivin following mouse sciatic nerve injury

(2009) S Amiri et al.   SPINAL CORD

Caspase-1 Inhibitor Prevents Neurogenic Pulmonary Edema After Subarachnoid Hemorrhage in Mice

(2009) Hidenori Suzuki et al.   STROKE

Ac-YVAD-CMK Decreases Blood–Brain Barrier Degradation by Inhibiting Caspase-1 Activation of Interleukin-1β in Intracerebral Hemorrhage Mouse Model

(2009) Bihua Wu et al.   Translational Stroke Research

Experimental cancer gene therapy by multiple anti-survivin hammerhead ribozymes

(2008) Qi Fei et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Cytokinesis: the final stop for the chromosomal passengers

(2008) Mar Carmena   BIOCHEMICAL SOCIETY TRANSACTIONS

Bexarotene activates the p53/p73 pathway in human cutaneous T-cell lymphoma

(2008) N. Nieto-Rementería et al.   BRITISH JOURNAL OF DERMATOLOGY

Low-Dose Radiation Enhances Survivin-Mediated Virotherapy against Malignant Glioma Stem Cells

(2008) S. Nandi et al.   CANCER RESEARCH

The cell biology of neural stem and progenitor cells and its significance for their proliferation versus differentiation during mammalian brain development

(2008) Lilla M Farkas et al.   CURRENT OPINION IN CELL BIOLOGY

Carrier-Mediated Uptake of 1-(2-Methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazolium Bromide (YM155 Monobromide), a Novel Small-Molecule Survivin Suppressant, into Human Solid Tumor and Lymphoma Cells

(2008) T. Minematsu et al.   DRUG METABOLISM AND DISPOSITION

Calcium ions in neuronal degeneration

(2008) Urszula Wojda et al.   IUBMB LIFE

PAK1 is a novel MEK-independent raf target controlling expression of the IAP survivin in M-CSF-mediated osteoclast survival

(2008) Elizabeth W. Bradley et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Role of Smac/DIABLO in cancer progression

(2008) Gustavo Martinez-Ruiz et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Nuclear translocation of X-linked inhibitor of apoptosis (XIAP) determines cell fate after hypoxia ischemia in neonatal brain

(2008) Juliet C. Russell et al.   JOURNAL OF NEUROCHEMISTRY

Vascular endothelial growth factor protects spinal cord motoneurons against glutamate-induced excitotoxicity via phosphatidylinositol 3-kinase

(2008) Laia Tolosa et al.   JOURNAL OF NEUROCHEMISTRY

Role of Dickkopf-1, an Antagonist of the Wnt/ -Catenin Signaling Pathway, in Estrogen-Induced Neuroprotection and Attenuation of Tau Phosphorylation

(2008) Q.-G. Zhang et al.   JOURNAL OF NEUROSCIENCE

Inhibition of Hsp90 Leads to Cell Cycle Arrest and Apoptosis in Human Malignant Pleural Mesothelioma

(2008) Junichi Okamoto et al.   Journal of Thoracic Oncology

Clinical and immunological evaluation of anti-apoptosis protein, survivin-derived peptide vaccine in phase I clinical study for patients with advanced or recurrent breast cancer

(2008) Tetsuhiro Tsuruma et al.   Journal of Translational Medicine

A Survivin-Ran Complex Regulates Spindle Formation in Tumor Cells

(2008) F. Xia et al.   MOLECULAR AND CELLULAR BIOLOGY

Signal transducer and activator of transcription 3 activation is associated with bladder cancer cell growth and survival

(2008) Chun-Liang Chen et al.   Molecular Cancer

Dual targeting of Raf and VEGF receptor 2 reduces growth and metastasis of pancreatic cancer through direct effects on tumor cells, endothelial cells, and pericytes

(2008) S. A. Lang et al.   MOLECULAR CANCER THERAPEUTICS

Antileukemia effects of xanthohumol in Bcr/Abl-transformed cells involve nuclear factor- B and p53 modulation

(2008) S. Monteghirfo et al.   MOLECULAR CANCER THERAPEUTICS

Survivin and heat shock protein 25/27 colocalize with cleaved caspase-3 in surviving reactive astrocytes following excitotoxicity to the immature brain

(2008) S. Villapol et al.   NEUROSCIENCE

Bcl-xL inhibits Bax-induced alterations in mitochondrial respiration and calcium release

(2008) A.V.F. Teles et al.   NEUROSCIENCE LETTERS

The protection of Bcl-2 overexpression on rat cortical neuronal injury caused by analogous ischemia/reperfusion in vitro

(2008) Hong Zhang et al.   NEUROSCIENCE RESEARCH

Bcl-xL induces Drp1-dependent synapse formation in cultured hippocampal neurons

(2008) H. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exploiting endogenous anti-apoptotic proteins for novel therapeutic strategies in cerebral ischemia

(2008) A RAMI et al.   PROGRESS IN NEUROBIOLOGY

A Dual Role of the NF-κB Pathway in Neonatal Hypoxic-Ischemic Brain Damage

(2008) Cora H. Nijboer et al.   STROKE

Neuroprotective effects of Ac.YVAD.cmk on experimental spinal cord injury in rats

(2008) Alper Karaoğlan et al.   SURGICAL NEUROLOGY

Bcl-2 or Bcl-XL gene therapy reduces apoptosis and increases plasticity protein GAP-43 in PC12 cells

(2007) Aniko Gal et al.   BRAIN RESEARCH BULLETIN

IGF1 Promotes Resistance to Apoptosis in Melanoma Cells through an Increased Expression of BCL2, BCL-X(L), and Survivin

(2007) Caroline Hilmi et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

A novel mimovirus vaccine containing survivin epitope with adjuvant IL-15 induces long-lasting cellular immunity and high antitumor efficiency

(2007) Zhao Yang et al.   MOLECULAR IMMUNOLOGY