Apoptosis or Necrosis in Acetaminophen-Induced Acute Liver Failure? New Insights From Mechanistic Biomarkers*

Oxidant stress, mitochondria, and cell death mechanisms in drug-induced liver injury: Lessons learned from acetaminophen hepatotoxicity

(2012) Hartmut Jaeschke et al.   DRUG METABOLISM REVIEWS

Development of an Accurate Index for Predicting Outcomes of Patients With Acute Liver Failure

(2012) Anna Rutherford et al.   GASTROENTEROLOGY

The mechanism underlying acetaminophen-induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation

(2012) Mitchell R. McGill et al.   JOURNAL OF CLINICAL INVESTIGATION

Molecular forms of HMGB1 and keratin-18 as mechanistic biomarkers for mode of cell death and prognosis during clinical acetaminophen hepatotoxicity

(2012) Daniel J. Antoine et al.   JOURNAL OF HEPATOLOGY

Mouse strain-dependent caspase activation during acetaminophen hepatotoxicity does not result in apoptosis or modulation of inflammation

(2011) C. David Williams et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Cytokeratin 18-based modification of the MELD score improves prediction of spontaneous survival after acute liver injury

(2010) Lars P. Bechmann et al.   JOURNAL OF HEPATOLOGY

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(2010) Daniel Antoine et al.   MOLECULAR MEDICINE