Reconstructed Ancestral Enzymes Impose a Fitness Cost upon Modern Bacteria Despite Exhibiting Favourable Biochemical Properties
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Title
Reconstructed Ancestral Enzymes Impose a Fitness Cost upon Modern Bacteria Despite Exhibiting Favourable Biochemical Properties
Authors
Keywords
Ancestral sequence reconstruction, Protein resurrection, Enzyme evolution, Fitness, Stability, 3-Isopropylmalate dehydrogenase
Journal
JOURNAL OF MOLECULAR EVOLUTION
Volume 81, Issue 3-4, Pages 110-120
Publisher
Springer Nature
Online
2015-09-09
DOI
10.1007/s00239-015-9697-5
References
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