Heterogeneity of $${\varvec{\rm d}}{\varvec{N}}/{\varvec{\rm d}}{\varvec{S}}$$ d N / d S Ratios at the Classical HLA Class I Genes over Divergence Time and Across the Allelic Phylogeny

HLA supertype variation across populations: new insights into the role of natural selection in the evolution of HLA-A and HLA-B polymorphisms

(2015) Rodrigo dos Santos Francisco et al.   IMMUNOGENETICS

Polymorphic HLA-C Receptors Balance the Functional Characteristics ofKIRHaplotypes

(2015) Hugo G. Hilton et al.   JOURNAL OF IMMUNOLOGY

Estimating the mutation load in human genomes

(2015) Brenna M. Henn et al.   NATURE REVIEWS GENETICS

Nonsynonymous Substitution Rate Heterogeneity in the Peptide-Binding Region Among Different HLA-DRB1 Lineages in Humans

(2014) Yoshiki Yasukochi et al.   G3-Genes Genomes Genetics

Why Do More Divergent Sequences Produce Smaller Nonsynonymous/Synonymous Rate Ratios in Pairwise Sequence Comparisons?

(2013) M. dos Reis et al.   GENETICS

Why Time Matters: Codon Evolution and the Temporal Dynamics of dN/dS

(2013) Carina F. Mugal et al.   MOLECULAR BIOLOGY AND EVOLUTION

Divergent allele advantage at MHC-DRB through direct and maternal genotypic effects and its consequences for allele pool composition and mating

(2013) T. L. Lenz et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Influence of HLA-C Expression Level on HIV Control

(2013) R. Apps et al.   SCIENCE

An integrated map of genetic variation from 1,092 human genomes

(2012)   NATURE

The IMGT/HLA database

(2012) James Robinson et al.   NUCLEIC ACIDS RESEARCH

RDP3: a flexible and fast computer program for analyzing recombination

(2010) D. P. Martin et al.   BIOINFORMATICS

Natural Selection and the Distribution of Identity-by-Descent in the Human Genome

(2010) Anders Albrechtsen et al.   GENETICS

The Positive Correlation between dN/dS and dS in Mammals Is Due to Runs of Adjacent Substitutions

(2010) Nina Stoletzki et al.   MOLECULAR BIOLOGY AND EVOLUTION

How pathogens drive genetic diversity: MHC, mechanisms and misunderstandings

(2010) L. G. Spurgin et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Nonlinear Dynamics of Nonsynonymous (dN) and Synonymous (dS) Substitution Rates Affects Inference of Selection

(2009) Jochen B. W. Wolf et al.   Genome Biology and Evolution

The Population Genetics of dN/dS

(2008) Sergey Kryazhimskiy et al.   PLoS Genetics