Analyzing Effects of Naturally Occurring Missense Mutations

Molecular modeling of mutant kinase domain of Btk, a Tec family member, for structure prediction

(2016) Iqbal Hina et al.   AFRICAN JOURNAL OF BIOTECHNOLOGY

Predicting folding free energy changes upon single point mutations

(2012) Zhe Zhang et al.   BIOINFORMATICS

In silico investigation of molecular mechanism of laminopathy caused by a point mutation (R482W) in lamin A/C protein

(2011) Vidya Rajendran et al.   AMINO ACIDS

Functional characterisation of a natural androgen receptor missense mutation (N771H) causing human androgen insensitivity syndrome

(2011) J. Cai et al.   ANDROLOGIA

Protein stability: a single recorded mutation aids in predicting the effects of other mutations in the same amino acid site

(2011) Gilad Wainreb et al.   BIOINFORMATICS

Origin, functional role, and clinical impact of Fanconi anemia FANCA mutations

(2011) M. Castella et al.   BLOOD

PoPMuSiC 2.1: a web server for the estimation of protein stability changes upon mutation and sequence optimality

(2011) Yves Dehouck et al.   BMC BIOINFORMATICS

Predicting the Melting Point of Human C-Type Lysozyme Mutants

(2011) Deeptak Verma et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Missense mutations in Otopetrin 1 affect subcellular localization and inhibition of purinergic signaling in vestibular supporting cells

(2011) Euysoo Kim et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

SNPeffect 4.0: on-line prediction of molecular and structural effects of protein-coding variants

(2011) G. De Baets et al.   NUCLEIC ACIDS RESEARCH

Structure-Based Analysis of Five Novel Disease-Causing Mutations in 21-Hydroxylase-Deficient Patients

(2011) Carolina Minutolo et al.   PLoS One

In Silico and In Vitro Investigations of the Mutability of Disease-Causing Missense Mutation Sites in Spermine Synthase

(2011) Zhe Zhang et al.   PLoS One

A missense mutation in CLIC2 associated with intellectual disability is predicted by in silico modeling to affect protein stability and dynamics

(2011) Shawn Witham et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Exploring the cause of drug resistance by the detrimental missense mutations in KIT receptor: computational approach

(2010) R. Rajasekaran et al.   AMINO ACIDS

Mutational hotspots in electron transfer flavoprotein underlie defective folding and function in multiple acyl-CoA dehydrogenase deficiency

(2010) Bárbara J. Henriques et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Phenylketonuria as a protein misfolding disease: The mutation pG46S in phenylalanine hydroxylase promotes self-association and fibril formation

(2010) João Leandro et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Computational analysis of missense mutations causing Snyder-Robinson syndrome

(2010) Zhe Zhang et al.   HUMAN MUTATION

Performance of protein stability predictors

(2010) Sofia Khan et al.   HUMAN MUTATION

Knowledge-based computational mutagenesis for predicting the disease potential of human non-synonymous single nucleotide polymorphisms

(2010) Majid Masso et al.   JOURNAL OF THEORETICAL BIOLOGY

Exploring the sequence determinants of amyloid structure using position-specific scoring matrices

(2010) Sebastian Maurer-Stroh et al.   NATURE METHODS

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

DrugScorePPI webserver: fast and accurate in silico alanine scanning for scoring protein–protein interactions

(2010) Dennis M. Kr�ger et al.   NUCLEIC ACIDS RESEARCH

Database resources of the National Center for Biotechnology Information

(2010) E. W. Sayers et al.   NUCLEIC ACIDS RESEARCH

Testing computational prediction of missense mutation phenotypes: Functional characterization of 204 mutations of human cystathionine beta synthase

(2010) Qiong Wei et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

A missense mutation, p.V132G, in the X-linked spermine synthase gene (SMS) causes Snyder-Robinson syndrome

(2009) L.E. Becerra-Solano et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Fast and accurate predictions of protein stability changes upon mutations using statistical potentials and neural networks: PoPMuSiC-2.0

(2009) Yves Dehouck et al.   BIOINFORMATICS

Computational Modeling of Structurally Conserved Cancer Mutations in the RET and MET Kinases: The Impact on Protein Structure, Dynamics, and Stability

(2009) Anshuman Dixit et al.   BIOPHYSICAL JOURNAL

Modeling Effects of Human Single Nucleotide Polymorphisms on Protein-Protein Interactions

(2009) Shaolei Teng et al.   BIOPHYSICAL JOURNAL

The polyamine metabolism genesornithine decarboxylaseandantizyme 2predict aggressive behavior in neuroblastomas with and withoutMYCNamplification

(2009) Dirk Geerts et al.   INTERNATIONAL JOURNAL OF CANCER

Mammalian polyamine metabolism and function

(2009) Anthony E. Pegg   IUBMB LIFE

MCCE2: Improving protein pKacalculations with extensive side chain rotamer sampling

(2009) Yifan Song et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

CHARMM: The biomolecular simulation program

(2009) B. R. Brooks et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm

(2009) Prateek Kumar et al.   Nature Protocols

Accurate Prediction of DnaK-Peptide Binding via Homology Modelling and Experimental Data

(2009) Joost Van Durme et al.   PLoS Computational Biology

Accurate prediction of stability changes in protein mutants by combining machine learning with structure based computational mutagenesis

(2008) M. Masso et al.   BIOINFORMATICS

A three-state prediction of single point mutations on protein stability changes

(2008) Emidio Capriotti et al.   BMC BIOINFORMATICS

Approaches and Resources for Prediction of the Effects of Non-Synonymous Single Nucleotide Polymorphism on Protein Function and Interactions

(2008) S. Teng et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Single Nucleotide Polymorphisms That Cause Structural Changes in the Cyclic AMP Receptor Protein Transcriptional Regulator of the Tuberculosis Vaccine Strain Mycobacterium bovis BCG Alter Global Gene Expression without Attenuating Growth

(2008) D. M. Hunt et al.   INFECTION AND IMMUNITY

Crystal Structure of Human Spermine Synthase

(2008) Hong Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

COILCHECK: An Interactive Server for the Analysis of Interface Regions in Coiled Coils

(2008) R. Sowdhamini et al.   PROTEIN AND PEPTIDE LETTERS

Ab initio folding of terminal segments with secondary structures reveals the fine difference between two closely related all-atom statistical energy functions

(2008) Yuedong Yang et al.   PROTEIN SCIENCE

Specific interactions for ab initio folding of protein terminal regions with secondary structures

(2008) Yuedong Yang et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Prediction by Graph Theoretic Measures of Structural Effects in Proteins Arising from Non-Synonymous Single Nucleotide Polymorphisms

(2008) Tammy M. K. Cheng et al.   PLoS Computational Biology

Distance-scaled, finite ideal-gas reference state improves structure-derived potentials of mean force for structure selection and stability prediction

(2002) Hongyi Zhou et al.   PROTEIN SCIENCE