Article
Materials Science, Multidisciplinary
Chang-Ching Weng, Tsu-An Yang, Yaw-Kuen Li
Summary: In this study, multi-functional nanoparticles with targeting, thermal, and pH-sensitive features were fabricated for controlled drug release. The nanoparticles exhibited high drug-loading content and showed potential for therapeutic applications through photothermal effects and targeted delivery to tumor cells.
MATERIALS & DESIGN
(2021)
Article
Biophysics
Lumin Yang, Xiaoduo Zhao, Jing Zhang, Shuanhong Ma, Lei Jiang, Qiangbing Wei, Meirong Cai, Feng Zhou
Summary: In this study, a novel biomimetic nanoparticles lubricant, CS-PS, was synthesized and demonstrated to have excellent lubrication performance and drug carrier properties, making it a promising option for the treatment of osteoarthritis.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2021)
Article
Polymer Science
Abeer M. Beagan, Ahlam A. Alghamdi, Shatha S. Lahmadi, Majed A. Halwani, Mohammed S. Almeataq, Abdulaziz N. Alhazaa, Khalid M. Alotaibi, Abdullah M. Alswieleh
Summary: The study successfully developed pH-sensitive nanocarriers for tumor-targeted drug delivery via the folate receptor. The nanoparticles exhibited excellent biocompatibility and minimal toxicity when exposed to MCF-7 and MCF-7 ADR cells.
Article
Medicine, Research & Experimental
Anja Sadzak, Mihael Erakovic, Suzana Segota
Summary: Flavonoids, natural antioxidants, have potential in photodynamic cancer treatment but degrade at physiological pH. Studying their oxidation kinetics helps understand degradation and analyze release data. Incorporating flavonoids into magnetic nanocarriers can mitigate degradation and enhance solubility, with release controlled by magnetic fields. A new analytical approach combining ALS and multilinear regression is presented for considering flavonoid autoxidation in release studies.
MOLECULAR PHARMACEUTICS
(2023)
Review
Biochemistry & Molecular Biology
Francesca Grilli, Parisa Hajimohammadi Gohari, Shan Zou
Summary: Functionalized graphene oxide (GO) nanoparticles play an important role in drug delivery systems by enabling intelligent release and targeted delivery to tumor sites. However, the toxicity and biocompatibility of GO-based formulations need to be evaluated and methods to reduce accumulation in non-specific tissues should be explored.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Applied
Shiyuan Peng, Baihao Huang, Yizhen Lin, Gongcui Pei, Lijuan Zhang
Summary: This study investigated the application of mesoporous silica nanoparticles (MSN) in drug delivery. The results showed that the structure and surface modification of MSN affect the drug loading and release properties. Hexagonal pore MSN-NH2 and MSN-PDA demonstrated better combined release performance in terms of pH-responsive performance and sustained release effect.
MICROPOROUS AND MESOPOROUS MATERIALS
(2022)
Article
Chemistry, Physical
Xinyu Lei, Yi Zhou, Xianhao Liu, Lingchang Kong, Libing Liao, Yuxin Li, Meng Liu, Lintao Tian, Wenxiu Rao, Guocheng Lv
Summary: In this study, a drug nanocarrier with effective pH-responsive properties based on natural halloysite nanotubes (Hal) was designed and investigated. The anisotropic surfaces of Hal allow for diverse charges under different pH, enabling electrostatic attraction or repulsion between the nanocarrier and drug molecules. Chitosan and pectin were self-assembled on Hal through electrostatic attraction to achieve dual encapsulation and pH-responsive drug release in the gut.
APPLIED CLAY SCIENCE
(2023)
Review
Pharmacology & Pharmacy
Ilker S. Bayer
Summary: Polysaccharides are complex molecules with exceptional properties and can be chemically modified. They have increased application in drug encapsulation and release in nanoscale synthesis due to their biocompatibility and biodegradability. This review focuses on studying sustained drug release from nanoscale polysaccharides, particularly drug release kinetics and mathematical modeling. It highlights the importance of modeling in predicting the behavior of specific polysaccharide matrices and reducing experimental trial and error.
Article
Pharmacology & Pharmacy
Madhappan Santhamoorthy, Vanaraj Ramkumar, Kokila Thirupathi, Lalitha Gnanasekaran, Vanitha Karuppannan, Thi Tuong Vy Phan, Seong-Cheol Kim
Summary: In this study, L-lysine modified mesoporous silica nanoparticles (MS@Lys NPs) were synthesized for the delivery of the anticancer drug curcumin (Cur) to cancer cells. The functionalization of L-lysine groups onto the mesopore channel surfaces of MS@GPTS NPs was achieved through a ring-opening reaction. The structural properties of MS@Lys NPs were examined using various instrumental techniques. The drug loading and pH-responsive drug delivery behavior of MS@Lys NPs were investigated using curcumin as a model drug, and their cytocompatibility and cell uptake behavior were evaluated using MDA-MB-231 cells. The results suggest that MS@Lys NPs have potential for pH-responsive drug delivery in cancer therapy.
Article
Polymer Science
Ngoc-Hang Truong-Thi, Ngoc Hoi Nguyen, Dinh Tien Dung Nguyen, Tuan Ngan Tang, Thi Hiep Nguyen, Dai Hai Nguyen
Summary: In this study, a drug delivery system based on mesoporous silica nanoparticles modified with heparin was fabricated to achieve sustainable and pH-responsive release of Platinum-based drugs. The modified nanoparticles showed high uniform spherical shape with a diameter of 89.03 +/- 4.49 nm, and had a loading capacity of cisplatin twice as the bare nanoparticles. The amount of drug released in tumor microenvironment (pH 5.8) was significantly higher than that released in physiological environment (pH 7.4). Cell toxicity assay confirmed the biocompatibility of the modified nanoparticles on MCF-7 cells. These results suggest that the heparin-modified nanoparticles have great potential as nanocarriers for chemotherapy with effectively loading ability and sustained release of Platinum-based drugs with pH response.
EUROPEAN POLYMER JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Sreekanth Reddy Obireddy, Shirisha Bellala, Madhavi Chintha, Akkulanna Sake, Subha Marata Chinna Subbarao, Wing -Fu Lai
Summary: This study investigated the encapsulation and controlled release of favipiravir using three inorganic nanoparticulate modifiers. While the release mechanism of the drug was not significantly affected by the modifiers, the incorporation of different types of nanoparticles led to variations in porosity and hydrophilicity, which ultimately influenced the drug encapsulation efficiency and release sustainability.
ARABIAN JOURNAL OF CHEMISTRY
(2023)
Article
Nanoscience & Nanotechnology
De-Xiang Zhang, Terence Tieu, Lars Esser, Marcin Wojnilowicz, Chieh-Hua Lee, Anna Cifuentes-Rius, Helmut Thissen, Nicolas H. Voelcker
Summary: In this study, a method for modifying the internal and external surfaces of porous silicon nanoparticles (pSiNPs) was developed. The modified pSiNPs showed excellent colloidal stability in a cell culture medium and the drug release kinetics could be fine-tuned by the combination of internal and external surface modifications. Moreover, the drug-loaded and peptide-functionalized nanoparticles exhibited enhanced cytotoxicity against prostate carcinoma cells.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Materials Science, Multidisciplinary
Gamze Kocal, Burcu Oktay, Gunes Ozen Eroglu, Serap Erdem Kuruca, Soner Cubuk, Nilhan Kayaman Apohan
Summary: This study successfully prepared mesoporous HAp nanoparticles with fluorescent and pH-responsive properties, and controlled the release rate of anticancer drugs through the design of nanoplatforms. The DOX@HAp/terpolymer nanoparticles exhibited different drug release characteristics under different pH conditions, showing high biocompatibility and inducing apoptosis of cancer cells.
MATERIALS TODAY COMMUNICATIONS
(2021)
Article
Biochemistry & Molecular Biology
Bagher Kazemi Heragh, Shahrzad Javanshir, Gholam Reza Mahdavinia, Mohammad Reza Naimi Jamal
Summary: A pH-responsive drug carrier was developed for controllable drug release in the gastric environment by grafting hydroxyapatite into a chitosan/nano-clay matrix. The co-precipitation method led to the penetration of hydroxyapatite nanoparticles inside the matrix, reducing drug release rate. The nanocomposite showed high sensitivity to pH and significantly decreased drug release rate in both gastric and intestinal environments.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Chemistry, Multidisciplinary
Mingxin Wang, Somia Yassin Hussain Abdalkarim, Ruixin Gong, Haibin Ji, Zhiming Chen, Yunfei Shen, Ying Zhou, Jiayuan Shen, Hou-Yong Yu
Summary: Polymer composite microspheres with excellent biodegradable and controlled long-term release characteristics have gained significant attention. However, producing polymer microspheres with controlled properties and customizable drug release is still a major challenge. In this study, dual-responsive cellulose nanocrystals were engineered and incorporated into polylactide composite microspheres to achieve controlled and sustained drug release behavior. The results demonstrated a temperature and pH dual-responsive controlled drug release capability of the composite microspheres, highlighting their potential as multifunctional drug delivery systems for medical applications.
Article
Chemistry, Multidisciplinary
Zan Gao, Ningning Song, Yunya Zhang, Xiaodong Li
Article
Chemistry, Physical
Zan Gao, Wanlu Yang, Jun Wang, Ningning Song, Xiaodong Li
Article
Multidisciplinary Sciences
Zan Gao, Clifton Bumgardner, Ningning Song, Yunya Zhang, Jingjing Li, Xiaodong Li
NATURE COMMUNICATIONS
(2016)
Article
Chemistry, Multidisciplinary
Zan Gao, Yosyp Schwab, Yunya Zhang, Ningning Song, Xiaodong Li
ADVANCED FUNCTIONAL MATERIALS
(2018)
Article
Multidisciplinary Sciences
Hai Wang, Zan Gao, Xuanyou Liu, Pranay Agarwal, Shuting Zhao, Daniel W. Conroy, Guang Ji, Jianhua Yu, Christopher P. Jaroniec, Zhenguo Liu, Xiongbin Lu, Xiaodong Li, Xiaoming He
NATURE COMMUNICATIONS
(2018)
Article
Chemistry, Multidisciplinary
Zan Gao, Ningning Song, Yunya Zhang, Yosyp Schwab, Jiajun He, Xiaodong Li
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2018)
Article
Chemistry, Physical
Rui Gao, Qi Liu, Jun Wang, Jingyuan Liu, Wanlu Yang, Zan Gao, Lianhe Liu
APPLIED SURFACE SCIENCE
(2014)
Article
Chemistry, Multidisciplinary
Xingming Zhang, Jing Ma, Wanlu Yang, Zan Gao, Jun Wang, Qi Liu, Jingyuan Liu, Xiaoyan Jing
Article
Chemistry, Physical
Wanlu Yang, Zan Gao, Jing Ma, Xingming Zhang, Jun Wang
JOURNAL OF ALLOYS AND COMPOUNDS
(2014)
Article
Chemistry, Physical
Wanlu Yang, Zan Gao, Ningning Song, Yunya Zhang, Yingchao Yang, Jun Wang
JOURNAL OF POWER SOURCES
(2014)
Article
Chemistry, Physical
Bin Wang, Qi Liu, Zhongyu Qian, Xiaofei Zhang, Jun Wang, Zhanshuang Li, Huijun Yan, Zan Gao, Fangbo Zhao, Lianhe Liu
JOURNAL OF POWER SOURCES
(2014)
Article
Chemistry, Multidisciplinary
Ningning Song, Yunya Zhang, Zan Gao, Xiaodong Li
Article
Nanoscience & Nanotechnology
Jiadeng Zhu, Zan Gao, Malgorzata Kowalik, Kaushik Joshi, Chowdhury M. Ashraf, Mikhail I. Arefev, Yosyp Schwab, Clifton Bumgardner, Kenneth Brown, Diana Elizabeth Burden, Liwen Zhang, James W. Klett, Leonid V. Zhigilei, Adri C. T. van Duin, Xiaodong Li
ACS APPLIED MATERIALS & INTERFACES
(2019)
Article
Multidisciplinary Sciences
Zan Gao, Jiadeng Zhu, Siavash Rajabpour, Kaushik Joshi, Malgorzata Kowalik, Brendan Croom, Yosyp Schwab, Liwen Zhang, Clifton Bumgardner, Kenneth R. Brown, Diana Burden, James William Klett, Adri C. T. van Duin, Leonid Zhigilei, Xiaodong Li
Article
Multidisciplinary Sciences
Ningning Song, Zan Gao, Xiaodong Li
Article
Chemistry, Physical
Wenjing Tan, Chunmei Gao, Shifeng Ji, Yunqing Xing, Yi Guo, Baogui Liang
Summary: Membrane separation technology is widely used in wastewater treatment due to its cost-effectiveness and productivity. However, organic membrane fouling caused by humic acid is a major barrier to its further development. This study successfully addressed this issue through the production of composite materials and self-cleaning membranes, providing beneficial strategies and solutions for membrane contamination problems.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2024)
Article
Chemistry, Physical
Qichang Peng, Qingdong Ruan, Bin Wang, Jinyuan Liu, Chao Huang, Xingwang Zhu, Dan Li, Liangliang Liu, Yinchuan Wang, Xiaolin Zhang, Jia Yan, Paul K. Chu, Hui Xu
Summary: The escalating issue of water pollution has led to significant attention in the field of photocatalysis. In this study, OV-Sb2WO6-X photocatalyst with oxygen vacancies was synthesized, which exhibited enhanced charge separation efficiency and improved photocatalytic activity. The introduction of oxygen vacancies was successfully controlled and characterized, and the modified photocatalyst showed superior degradation efficiency for dye wastewater treatment.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2024)
Article
Chemistry, Physical
Wangcheng Zhang, Cunchuan Zheng, Hu Xie, Weichao Du
Summary: By using a specific curing agent ETB, the problem of dispersion and stability for oily epoxy resin in cement slurry system has been successfully solved. The application of the emulsified curing agent ETB in oilfield cement slurry system shows good rheological performance, resistance to high temperature and high pressure water loss, and corrosion resistance.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2024)
Article
Chemistry, Physical
O. I. Krivonos, A. Babenko, O. B. Belskaya
Summary: This study synthesized biochar based on sapropel and investigated the effects of chemical modification on its textural characteristics, acid-base properties, and adsorption properties. The results showed that the chemical modification increased the fraction of micropores, specific surface area, and changed the surface properties of biochar. The experiment also revealed that biochar pretreated with alkali exhibited the maximum adsorption capacity for copper ions. A conceptual model identifying the mechanisms of copper adsorption on sapropel-based biosorbent was proposed.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2024)
Article
Chemistry, Physical
H. Lachhab, N. Benzbiria, A. Titi, S. Echihi, M. E. Belghiti, Y. Karzazi, A. Zarrouk, R. Touzani, C. Jama, F. Bentiss
Summary: The corrosion inhibitory potency of two new pyrimidine-pyrazole derivatives, PPA and PPC, was evaluated for mild steel in 1 M HCl. The results showed enhanced inhibition activities with increased concentration, reaching maximal values of 91.15% and 92.39% for PPA and PPC, respectively. However, the mitigation potency decreased with increasing temperature. SEM and XPS analysis revealed that PPA and PPC adsorbed on the mild steel surface, forming a shielding layer that prevented the dissolution of the steel in the acidic solution.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2024)
Article
Chemistry, Physical
Shanmugapriya Sivalingam, D. Jeya Sundara Sharmila, Goutham Golla, Lakshmanan Arunachalam, Tarunendu Singh, G. Karthikeyan, A. Shanthi, Kannan Malaichamy
Summary: This study aims to develop a nano-biofungicide comprising of volatile essential oil molecules to enhance its efficacy in the field of agriculture through easily scalable green synthesis technique. The nano biofungicide was prepared through one pot hot melt ultrasonication technique with easy water dispersibility and long term stability. The physico-chemical analysis revealed that, nano bio-fungicides were amorphous sphere-shaped nanoparticles with low melting point. The encapsulation efficiency of major components of essential oil was determined, and it was found that they followed Higuchi model of release kinetics. The essential oil loaded nanostructured lipid carrier showed significantly higher mycelial growth inhibition compared to pure essential oil, indicating enhanced bio-efficacy.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2024)
Article
Chemistry, Physical
Yinlong Li, Yingqing Zhan, Yiwen Chen, Hongshan Jia, Ximin Chen, Fei Zhu, Xulin Yang
Summary: In this study, ZnO quantum dots decorated MXene nanosheets were used as a functional filler for waterborne epoxy coating. The improved dispersion and synergy of ZnO QDs and MXene nanosheets enhanced the anticorrosion performance of the coating.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2024)
Article
Chemistry, Physical
Fucheng Guan, Jing Tao, Qiang Yao, Zheng Li, Yihang Zhang, Shi Feng, Jianbin Sun, Qiang Yang, Xuecui Song, Jing Guo, Yuanfa Liu
Summary: This paper presents a method for preparing adsorbent materials based on biomass that can efficiently adsorb methylene blue. The experimental results show that the material has a hierarchical structure, high adsorption capacity, and reusability.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2024)
Article
Chemistry, Physical
Pengfei Hu, Zuli Mo, Weiliang Wang, Chengzhe Li, Zhaojia Guo, Guanqing Lin, Zhimin Guo
Summary: This study developed a novel in-situ particle vision and measurement (PVM) system to investigate heterocoagulation between coarse and fine particles in mineral processing. The experimental results showed that the degree of heterocoagulation decreased with increasing pH and stirring speed. Furthermore, under certain hydrodynamic conditions, coal particles were more distributed at the rear of the glass bead.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2024)
Article
Chemistry, Physical
Tanveer ul Haq Zia, Anwar ul Haq Ali Shah, Behisht Ara, Kashif Gul
Summary: A label-free immunosensor for detection of hepatitis C core antigen was fabricated using a ternary nanocomposite based on polypyrrole, silver doped zinc oxide, and exfoliated graphene. The immunosensor demonstrated low detection limit, high selectivity, and stability.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2024)
Article
Chemistry, Physical
Xiaoyan Feng, Jiachen Li, Lijun Liang, Linli Zhu, Sa Liu, Li Ren
Summary: In this study, polystyrene divinylbenzene microspheres were surface-modified by poly(carboxybetaine methacrylate) to develop an efficient hemoperfusion adsorbent for the removal of protein-bound toxins. The modified microspheres showed increased adsorption capacity and better biocompatibility, making them promising for clinical hemoperfusion therapy.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2024)
Article
Chemistry, Physical
Xiaoye Bi, Dong Xue, Yunpeng Wang, Chencheng Lv, Zexiong Li, Tao Zhao
Summary: This research aimed to develop a durable and formaldehyde-free flame retardant treatment for cotton fabrics. The results demonstrated successful grafting of phosphorous acid (PA) onto cotton fabrics, leading to enhanced flame resistance while maintaining the desired fabric characteristics.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2024)
Article
Chemistry, Physical
Ruolin Wang, Wenjuan Sun, Haisheng Han, Dongping Tao
Summary: This study finds that Al-starch colloidal depressants can effectively inhibit the flotation of ultrafine calcite and chlorite, and increase the grade of valuable minerals. The chemisorption of Al-starch on mineral surface changes the functional group peaks and generates new O-Al functional groups.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2024)
Article
Chemistry, Physical
Wondimu K. Wakejo, Ali Maged, Beteley T. Meshesha, Joon W. Kang, Abayneh G. Demesa, Sandip Chakrabarti, Thallada Bhaskar, Ashok Kumar Gupta, Amit Bhatnagar
Summary: Simultaneously removing different pharmaceutical pollutants from wastewater is an important environmental issue, and the use of a system that can remove multiple contaminants at once is necessary. Functionalized biochar (FBC) has been found to be effective in simultaneously removing acetaminophen and ciprofloxacin and other pharmaceutical pollutants.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2024)
Article
Chemistry, Physical
Yu Wang, Fengwen Yan, Jie Wu, Zhijun Huang, Liuting Song, Shunda Yuan
Summary: In this study, Cu single atoms are anchored on the external surface of g-C3N4 nanofibers to maximize atom utilization. This catalyst exhibits excellent Fenton-like catalytic activity and good stability due to the full utilization of Cu active sites.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2024)