Article
Polymer Science
Parvaneh Gheysoori, Azin Paydayesh, Maryam Jafari, Hamed Peidayesh
Summary: This study focuses on the development of thermoresponsive nanocomposite hydrogels for minimally invasive drug delivery. Gelatin-based hydrogels with poly (N-isopropylacrylamide) (PNIPAM) were prepared using response surface methodology. The PNIPAM nanoparticles showed successful polymerization and a reversible sol-gel transition close to body temperature. These nanocomposite hydrogels demonstrated antibacterial activity and good potential for targeted drug delivery.
EUROPEAN POLYMER JOURNAL
(2023)
Article
Chemistry, Analytical
Jung Gi Choi, Hocheol Gwac, Yongwoo Jang, Christopher Richards, Holly Warren, Geoffrey Spinks, Seon Jeong Kim
Summary: The diving and surfacing device fabricated from thermo-sensitive poly(N-isopropylacrylamide) or a poly(N-isopropylacrylamide)-containing hydrogel can exhibit fast and reversible diving/surfacing cycles in response to changing temperature. Modulation of the interaction between poly(N-isopropylacrylamide) chains and water molecules at different temperatures allows for control of gel density through swelling and de-swelling, enabling the gel to surface in water when heated and sink when cooled. Reversible diving/surfacing cycles of the device can also be achieved when exposed to electrical and ultrasonic stimuli.
Article
Nanoscience & Nanotechnology
Yu-Chen Huang, Qian-Pu Cheng, U-Ser Jeng, Shan-hui Hsu
Summary: The development of hydrogel-based actuators with programmable deformation has attracted much attention in both fundamental and applied research. In this study, a temperature-responsive and biodegradable gelatin methacryloyl (GelMA)-poly(N-isopropylacrylamide) hydrogel (GN hydrogel) was explored as the active layer of a bilayer actuator. The optimized bilayer hydrogel actuator exhibited large, reproducible, and anisotropic bending, and has potential applications in biomimetic devices, artificial muscles, and soft robotics for biomedical purposes.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Polymer Science
Yanrong Luo, Chunlan Lu, Xiaolin Zhang, Shiping Zhan
Summary: In this study, acylated chitosan macromolecular crosslinkers (MCS) were prepared and used as the cross-linking agent to synthesize a series of thermosensitive hydrogels. The hydrogels showed a homogeneous pore structure and a low critical solution temperature of 36.66 celcius, indicating good hydrophilicity. The results suggest that the P(NIPAM-co-MA)/MCS hydrogels have the potential to be applied in biomedical, drug delivery, or absorption fields.
IRANIAN POLYMER JOURNAL
(2023)
Article
Polymer Science
Renhua Yao, Xiaoqin Yu, Rui Deng, Huarong Zou, Qingwen He, Wenfeng Huang, Chunxiao Li, Kun Zou
Summary: By creating interpenetrating polymer network hydrogels, the easy swelling and drug release properties of konjac glucomannan hydrogels can be avoided, improving the bioavailability of drugs and making it suitable for treating colonic diseases.
Article
Nanoscience & Nanotechnology
Kai Wang, Guoqi Chen, Sen Weng, Linxi Hou, Dezhan Ye, Xiancai Jiang
Summary: A thermo-responsive PNIPAM/HPMC hydrogel was prepared using a simple one-step low-temperature polymerization method, achieving high transmittance, high solar modulation, low phase-transition temperature, and excellent high-temperature thermal stability simultaneously. The hydrogel exhibited high light transmittance (90.82%) and good mechanical properties and thermal stability. It also showed a low phase-transition temperature (about 32 degrees C) and high solar modulation (81.52%), making it an ideal material for thermochromic smart windows.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Polymer Science
Qichen Tang, Shanhua Qian, Weiwei Chen, Xiaofei Song, Jianfeng Huang
Summary: In this study, Ca-alginate/PNIPAm hydrogels were prepared through physical crosslinking and chemical crosslinking, and their properties were characterized. The results showed that the pure PNIPAm hydrogel obtained using thermal initiation polymerization exhibited better swelling and temperature-responsive properties compared to the hydrogel using ultraviolet polymerization. The mechanical properties of the Ca/PNIPAm hydrogel were enhanced when the SA concentration exceeded 8 wt%.
POLYMER INTERNATIONAL
(2023)
Article
Chemistry, Multidisciplinary
Jing Tian, Chengguo Jin, Xudong Wu, Cong Liao, Jiangping Xie, Yajun Luo
Summary: Dynamic windows that switch between transparent and opaque states can be used in buildings to reduce energy consumption. Durable PU-PNIPAmn copolymers were synthesized to improve the mechanical properties of the hydrogel, which can form a film alone. These temperature-sensitive films can switch between transparent and opaque states in less than 10 minutes and maintain optical contrast, switching speed, and uniformity after at least 100 cycles.
Article
Polymer Science
Junta Sano, Shigeki Habaue
Summary: Novel interpenetrating polymer networks (IPNs) composed of poly(N-isopropylacrylamide) (poly-NIPAM) and polyethers, including polyethylene glycol (PEG) and poly(tetramethylene oxide), were synthesized with the presence of polysiloxane. A novel one-step method was developed for constructing the IPN structure using end-capped polyethers containing trimethoxysilyl moieties. The synthesized IPNs exhibited temperature-responsive volume changes in water and specific color-change responses to chemical stimuli when both poly-NIPAM and PEG components were present in gel form.
Article
Chemistry, Physical
Zhibin Zhang, Xi Wang, Hongyan Li, Gengchen Liu, Kaiying Zhao, Yajun Wang, Zheng Li, Jianying Huang, Zhiwei Xu, Yuekun Lai, Xiaoming Qian, Songnan Zhang
Summary: In this study, an innovative atmospheric water harvester combining hydrogel and 3D raised-fabric was developed, which exhibited excellent photothermal conversion performance and adsorption capacity, making it effective for water collection and storage.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2024)
Article
Polymer Science
Hangjing Zhang, Tianyuan Gao, Shuai Zhang, Peng Zhang, Rui Li, Ning Ma, Hao Wei, Xinyue Zhang
Summary: A cost-effective and facile method to synthesize a conductive poly(N-isopropylacrylamide) hydrogel doped with deep eutectic solvent (DES) is proposed in this study, demonstrating enhanced mechanical strength and thermal-dependent conductivity. The hybrid hydrogels show potential applications in flexible electronic sensors and environmental response elements.
MACROMOLECULAR CHEMISTRY AND PHYSICS
(2021)
Article
Polymer Science
Yiluo Hu, Younghyun Shin, Sohyun Park, Jae-pil Jeong, Yohan Kim, Seunho Jung
Summary: Self-healing and temperature/pH-responsive hydrogels were prepared by using oxidized succinoglycan (OSG) and a poly (N-isopropyl acrylamide-co-acrylamide) [P(NIPAM-AM)] copolymer. OSG, synthesized from succinoglycan (SG) isolated directly from soil microorganisms, showed improved elasticity, thermal stability, self-healing ability, and tensile strength compared to P(NIPAM-AM) hydrogels. The OSG/P(NIPAM-AM) hydrogels also exhibited effective temperature/pH-responsive drug release and non-toxicity, suggesting their potential for biomedical applications such as drug delivery systems, wound healing, scaffolds, and tissue engineering.
Article
Materials Science, Multidisciplinary
Ying Cao, Wenjiao Li, Fengyu Quan, Yanzhi Xia, Zhong Xiong
Summary: In this study, Fe3O4 nanoparticles were incorporated into poly(N-isopropylacrylamide-acrylamide) hydrogel to achieve green-light-responsive volume change through photothermal effect. A boomerang-like hydrogel actuator was also designed and fabricated, successfully driving a floating foam in water in a circular returning movement.
FRONTIERS IN MATERIALS
(2022)
Article
Polymer Science
Ruiying He, Dong Zhou, Lan Xiao, Yulin Li
Summary: This study presents a new design of a moisturizing and antimicrobial hydrogel using a green solvent (glycerol) as a cross-linking agent and gold nanoparticles reduced by Chlorella extract as an antimicrobial approach. The synthesized gold nanoparticles (AuNPs@Chlorella) showed environmentally friendly and bio-safe properties. Rheometry analysis confirmed the enhanced stability of the gelatin hydrogels with the addition of glycerol and AuNPs. The gelatin-glycerol hydrogels containing AuNPs@Chlorella are potentially promising alternatives for wound healing dressings.
Article
Chemistry, Applied
Roxane Abdel-Gawad, Rihab Osman, Gehanne A. S. Awad, Nahed Mortada
Summary: Interactive wound dressings combining healing and antimicrobial potentials, utilizing a three-dimensional structured matrix constructed with natural bio-macromolecules, demonstrated significant wound healing effects and antimicrobial activity. Injured rat experiments confirmed its excellent wound healing ability and minimal oxidative stress.
CARBOHYDRATE POLYMERS
(2024)
