Novel synthetic chalcone-coumarin hybrid for Aβ aggregation reduction, antioxidation, and neuroprotection

The Potential of Indole/Indolylquinoline Compounds in Tau Misfolding Reduction by Enhancement of HSPB1

(2016) Kuo-Hsuan Chang et al.   CNS Neuroscience & Therapeutics

The potential of synthetic indolylquinoline derivatives for Aβ aggregation reduction by chemical chaperone activity

(2016) Kuo-Hsuan Chang et al.   NEUROPHARMACOLOGY

Preparation of Furo[3,2-c]coumarins from 3-Cinnamoyl-4-hydroxy-2H-chromen-2-ones and Acyl Chlorides: A Bu3P-Mediated C-Acylation/Cyclization Sequence

(2015) Chia-Jui Lee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The genetic landscape of Alzheimer disease: clinical implications and perspectives

(2015) Caroline Van Cauwenberghe et al.   GENETICS IN MEDICINE

Resveratrol decreases the insoluble Aβ1–42 level in hippocampus and protects the integrity of the blood–brain barrier in AD rats

(2015) H.F. Zhao et al.   NEUROSCIENCE

Synaptic Therapy in Alzheimer’s Disease: A CREB-centric Approach

(2015) Andrew F. Teich et al.   Neurotherapeutics

Lico A Enhances Nrf2-Mediated Defense Mechanisms againstt-BHP-Induced Oxidative Stress and Cell Death via Akt and ERK Activation in RAW 264.7 Cells

(2015) Hongming Lv et al.   Oxidative Medicine and Cellular Longevity

Synthesis and characterization of 1H-phenanthro[9,10-d]imidazole derivatives as multifunctional agents for treatment of Alzheimer's disease

(2014) Jinggong Liu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Licochalcone A activates Nrf2in vitroand contributes to licorice extract-induced lowered cutaneous oxidative stressin vivo

(2014) Jochen Kühnl et al.   EXPERIMENTAL DERMATOLOGY

Aqueous extract of Glycyrrhiza inflata inhibits aggregation by upregulating PPARGC1A and NFE2L2–ARE pathways in cell models of spinocerebellar ataxia 3

(2014) Chiung-Mei Chen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nrf2 Regulates Neurogenesis and Protects Neural Progenitor Cells Against Aβ Toxicity

(2014) Virve Kärkkäinen et al.   STEM CELLS

Overexpression of Hsp27 ameliorates symptoms of Alzheimer's disease in APP/PS1 mice

(2013) Melinda Erzsébet Tóth et al.   CELL STRESS & CHAPERONES

Enantioselective Total Synthesis of (−)-Blennolide A

(2013) Lutz F. Tietze et al.   CHEMISTRY-A EUROPEAN JOURNAL

The Synthesis and Evaluation of Novel Hydroxyl Substituted Chalcone Analogs with in Vitro Anti-Free Radicals Pharmacological Activity and in Vivo Anti-Oxidation Activity in a Free Radical-Injury Alzheimer’s Model

(2013) Ying Pan et al.   MOLECULES

The protective effect of hyperbaric oxygen and Ginkgo biloba extract on A?25?35-induced oxidative stress and neuronal apoptosis in rats

(2012) XiaoQiang Tian et al.   BEHAVIOURAL BRAIN RESEARCH

Preparation of functional benzofurans and indoles via chemoselective intramolecular Wittig reactions

(2012) Yu-Ting Lee et al.   CHEMICAL COMMUNICATIONS

Coumarins as Antioxidants

(2012) I. Kostova et al.   CURRENT MEDICINAL CHEMISTRY

The Toxicity of Amyloid ß Oligomers

(2012) Li Na Zhao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A plant cell-based system that predicts aβ42 misfolding: Potential as a drug discovery tool for Alzheimer's disease

(2012) Tiehan Zhao et al.   MOLECULAR GENETICS AND METABOLISM

A review on coumarins as acetylcholinesterase inhibitors for Alzheimer’s disease

(2011) Preet Anand et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Flavonoid engineering of flax potentiate its biotechnological application

(2011) Magdalena Żuk et al.   BMC BIOTECHNOLOGY

Downregulation of CREB expression in Alzheimer's brain and in Aβ-treated rat hippocampal neurons

(2011) Subbiah Pugazhenthi et al.   Molecular Neurodegeneration

An efficient synthesis of flavans from salicylaldehyde and acetophenone derivatives

(2011) Ofentse Mazimba et al.   TETRAHEDRON LETTERS

The small heat shock protein Hsp27 protects cortical neurons against the toxic effects of β-amyloid peptide

(2009) Michael King et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Effect of Purple Sweet Potato Anthocyanins on β-Amyloid-Mediated PC-12 Cells Death by Inhibition of Oxidative Stress

(2009) Junli Ye et al.   NEUROCHEMICAL RESEARCH

Catalpol protects primary cultured cortical neurons induced by Aβ1–42 through a mitochondrial-dependent caspase pathway

(2009) Jian Hua Liang et al.   NEUROCHEMISTRY INTERNATIONAL

Probing Hydrogen Bonding to Bound Dioxygen in Synthetic Models for Heme Proteins: The Importance of Precise Geometry

(2008) Henry Dube et al.   CHEMISTRY-A EUROPEAN JOURNAL

Mitochondria, Mitochondrial DNA and Alzheimers Disease. What Comes First?

(2008) Michelangelo Mancuso et al.   Current Alzheimer Research

Amyloid-cholinesterase interactions

(2008) Nibaldo C. Inestrosa et al.   FEBS Journal

Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease

(2008) Ilya Bezprozvanny et al.   TRENDS IN NEUROSCIENCES