Defining the role of glucocorticoids in inflammation

Glucocorticoid hormone treatment enhances the cytokine production of regulatory T cells by upregulation of Foxp3 expression

(2018) Emese Ugor et al.   IMMUNOBIOLOGY

Glucocorticoids Modulate Th1 and Th2 Responses in Asthmatic Mouse Models by Inhibition of Notch1 Signaling

(2018) Chengping Hu et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Impaired resolution of DSS-induced colitis in mice lacking the glucocorticoid receptor in myeloid cells

(2018) Garrit K. Meers et al.   PLoS One

GR-regulating Serine/Threonine Kinases: New Physiologic and Pathologic Implications

(2018) Tomoshige Kino   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Therapeutic Mechanisms of Glucocorticoids

(2018) Jolien Vandewalle et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The glucocorticoid receptor in recipient cells keeps cytokine secretion in acute graft-versus-host disease at bay

(2018) Tina Baake et al.   Oncotarget

Role of the glucocorticoid-induced leucine zipper gene in dexamethasone-induced inhibition of mouse neutrophil migration via control of annexin A1 expression

(2017) Erika Ricci et al.   FASEB JOURNAL

Glucocorticoids induce differentiation of monocytes towards macrophages that share functional and phenotypical aspects with erythroblastic island macrophages

(2017) Esther Heideveld et al.   HAEMATOLOGICA

Suppression of cytokine production by glucocorticoids is mediated by MKP-1 in human lung epithelial cells

(2017) Tiina Keränen et al.   INFLAMMATION RESEARCH

The FKBP51 Glucocorticoid Receptor Co-Chaperone: Regulation, Function, and Implications in Health and Disease

(2017) Gabriel Fries et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Glucocorticoids induce differentiation of monocytes towards macrophages that share functional and phenotypical aspects with erythroblastic island macrophages

(2017) Esther Heideveld et al.   HAEMATOLOGICA

Distinct Effects of Dexamethasone on Human Natural Killer Cell Responses Dependent on Cytokines

(2017) David J. Morgan et al.   Frontiers in Immunology

BCL-2 protects human and mouse Th17 cells from glucocorticoid-induced apoptosis

(2016) J. Banuelos et al.   ALLERGY

Lipid Management Guidelines from the Departments of Veteran Affairs and Defense: A Critique

(2016) Catherine S. Bennet et al.   AMERICAN JOURNAL OF MEDICINE

Interleukins 1 and 6 as main mediators of inflammation and cancer

(2016) O. S. Dmitrieva et al.   BIOCHEMISTRY-MOSCOW

Glucocorticoids and chronic inflammation

(2016) Rainer H. Straub et al.   RHEUMATOLOGY

Pain regulation by non-neuronal cells and inflammation

(2016) R.-R. Ji et al.   SCIENCE

New dimension of glucocorticoids in cancer treatment

(2016) Kai-Ti Lin et al.   STEROIDS

Annexin A1 and the Resolution of Inflammation: Modulation of Neutrophil Recruitment, Apoptosis, and Clearance

(2016) Michelle Amantéa Sugimoto et al.   Journal of Immunology Research

Lack of glucocorticoid-induced leucine zipper (GILZ) deregulates B-cell survival and results in B-cell lymphocytosis in mice

(2015) S. Bruscoli et al.   BLOOD

Glucocorticoid‐induced microRNA‐511 protects against TNF by down‐regulating TNFR1

(2015) Leen Puimège et al.   EMBO Molecular Medicine

Inflammatory Bowel Disease: An Overview of Immune Mechanisms and Biological Treatments

(2015) Bruno Rafael Ramos de Mattos et al.   MEDIATORS OF INFLAMMATION

One Hormone, Two Actions: Anti- and Pro-Inflammatory Effects of Glucocorticoids

(2015) Diana Cruz-Topete et al.   NEUROIMMUNOMODULATION

The Role of the Mediators of Inflammation in Cancer Development

(2015) José Veríssimo Fernandes et al.   PATHOLOGY & ONCOLOGY RESEARCH

Glucocorticoid receptor interacts with PNRC2 in a ligand-dependent manner to recruit UPF1 for rapid mRNA degradation

(2015) Hana Cho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The resolution of inflammation: Principles and challenges

(2015) Sarah E. Headland et al.   SEMINARS IN IMMUNOLOGY

Glucocorticoids regulate natural killer cell function epigenetically

(2014) Justin L. Eddy et al.   CELLULAR IMMUNOLOGY

Targeting glucocorticoid side effects: selective glucocorticoid receptor modulator or glucocorticoid-induced leucine zipper? A perspective

(2014) Emira Ayroldi et al.   FASEB JOURNAL

Roles for the Mitogen-activated Protein Kinase (MAPK) Phosphatase, DUSP1, in Feedback Control of Inflammatory Gene Expression and Repression by Dexamethasone

(2014) Suharsh Shah et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cancer-related inflammation and treatment effectiveness

(2014) Connie I Diakos et al.   LANCET ONCOLOGY

GILZ Promotes Production of Peripherally Induced Treg Cells and Mediates the Crosstalk between Glucocorticoids and TGF-β Signaling

(2014) Oxana Bereshchenko et al.   Cell Reports

TRPA1: A Transducer and Amplifier of Pain and Inflammation

(2013) Ari Koivisto et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Glucocorticoids suppress hypoxia-induced COX-2 and hypoxia inducible factor-1α expression through the induction of glucocorticoid-induced leucine zipper

(2013) Wonchung Lim et al.   BRITISH JOURNAL OF PHARMACOLOGY

Analysis of Glucocorticoid Receptors and Their Apoptotic Response to Dexamethasone in Male Murine B Cells During Development

(2013) Amanda L. Gruver-Yates et al.   ENDOCRINOLOGY

GILZ Overexpression Inhibits Endothelial Cell Adhesive Function through Regulation of NF- B and MAPK Activity

(2013) Q. Cheng et al.   JOURNAL OF IMMUNOLOGY

Ligand-Induced Repression of the Glucocorticoid Receptor Gene Is Mediated by an NCoR1 Repression Complex Formed by Long-Range Chromatin Interactions with Intragenic Glucocorticoid Response Elements

(2013) Sivapriya Ramamoorthy et al.   MOLECULAR AND CELLULAR BIOLOGY

Glucocorticoid inhibition of activation-induced cytidine deaminase expression in human B lymphocytes

(2013) Ann L. Benko et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Anti-Inflammatory Therapy in Chronic Disease: Challenges and Opportunities

(2013) I. Tabas et al.   SCIENCE

Glucocorticoid regulation of inflammation and its functional correlates: from HPA axis to glucocorticoid receptor dysfunction

(2012) Marni N. Silverman et al.   Annals of the New York Academy of Sciences

Psychosocial stress and inflammation in cancer

(2012) N.D. Powell et al.   BRAIN BEHAVIOR AND IMMUNITY

Glucocorticoid-resistant asthma and novel anti-inflammatory drugs

(2012) Christine R. Keenan et al.   DRUG DISCOVERY TODAY

Glucocorticoids inhibit lipopolysaccharide-mediated inflammatory response by downregulating microRNA-155: a novel anti-inflammation mechanism

(2012) Yijie Zheng et al.   FREE RADICAL BIOLOGY AND MEDICINE

How glucocorticoid receptors modulate the activity of other transcription factors: A scope beyond tethering

(2012) Dariusz Ratman et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The structural basis of direct glucocorticoid-mediated transrepression

(2012) William H Hudson et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Characterization of the Effects of Cross-Linking of Macrophage CD44 Associated with Increased Phagocytosis of Apoptotic PMN

(2012) Simon P. Hart et al.   PLoS One

Endogenous glucocorticoids in inflammation: contributions of systemic and local responses

(2012) RS Hardy et al.   SWISS MEDICAL WEEKLY

Widespread Negative Response Elements Mediate Direct Repression by Agonist- Liganded Glucocorticoid Receptor

(2011) Milan Surjit et al.   CELL

Glucocorticoids Sensitize the Innate Immune System through Regulation of the NLRP3 Inflammasome

(2011) John M. Busillo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glucocorticoids inhibit dendritic cell maturation induced by Toll-like receptor 7 and Toll-like receptor 8

(2011) Alexandre Larangé et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Chromatin accessibility pre-determines glucocorticoid receptor binding patterns

(2011) Sam John et al.   NATURE GENETICS

Glucocorticoid resistance in Crohn's disease and ulcerative colitis: an association study investigating GR and FKBP5 gene polymorphisms

(2011) P Maltese et al.   PHARMACOGENOMICS JOURNAL

Tumor suppressor protein (p)53, is a regulator of NF- B repression by the glucocorticoid receptor

(2011) S. H. Murphy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glucocorticoids promote survival of anti-inflammatory macrophages via stimulation of adenosine receptor A3

(2010) K. Barczyk et al.   BLOOD

Corticosterone exerts immunostimulatory effects on macrophages via endoplasmic reticulum stress

(2010) J.-Y. Zhou et al.   BRITISH JOURNAL OF SURGERY

Oxidative stress, inflammation, and cancer: How are they linked?

(2010) Simone Reuter et al.   FREE RADICAL BIOLOGY AND MEDICINE

The role of the glucocorticoid receptor in inflammation and immunity

(2010) Ulrike Baschant et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Prior exposure to glucocorticoids sensitizes the neuroinflammatory and peripheral inflammatory responses to E. coli lipopolysaccharide

(2009) Matthew G. Frank et al.   BRAIN BEHAVIOR AND IMMUNITY

Targeting Inflammatory Pathways for Prevention and Therapy of Cancer: Short-Term Friend, Long-Term Foe

(2009) B. B. Aggarwal et al.   CLINICAL CANCER RESEARCH

The relationship between the expression of the glucocorticoid receptor in biopsied colonic mucosa and the glucocorticoid responsiveness of ulcerative colitis patients

(2009) Sho-ichiro Fujishima et al.   CLINICAL IMMUNOLOGY

Compound A, a Plant Origin Ligand of Glucocorticoid Receptors, Increases Regulatory T Cells and M2 Macrophages to Attenuate Experimental Autoimmune Neuritis with Reduced Side Effects

(2009) Z. Zhang et al.   JOURNAL OF IMMUNOLOGY

Glucocorticoids increase CD4+CD25highcell percentage and Foxp3 expression in patients with multiple sclerosis

(2008) M. Braitch et al.   ACTA NEUROLOGICA SCANDINAVICA

Glucocorticoids inhibit degranulation of mast cells in allergic asthma via nongenomic mechanism

(2008) J. Zhou et al.   ALLERGY

Dose-related patterns of glucocorticoid-induced side effects

(2008) D Huscher et al.   ANNALS OF THE RHEUMATIC DISEASES

CD4+CD25+ regulatory T cells (TREG) in Systemic Lupus Erythematosus (SLE) patients: The possible influence of treatment with corticosteroids

(2008) N.A. Azab et al.   CLINICAL IMMUNOLOGY

Glucocorticoids induce an activated, anti-inflammatory monocyte subset in mice that resembles myeloid-derived suppressor cells

(2008) Georg Varga et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Molecular mechanisms regulating glucocorticoid sensitivity and resistance

(2008) Katherine L. Gross et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY