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Title
Histone deacetylases as targets for treatment of multiple diseases
Authors
Keywords
-
Journal
CLINICAL SCIENCE
Volume 124, Issue 11, Pages 651-662
Publisher
Portland Press Ltd.
Online
2013-02-15
DOI
10.1042/cs20120504
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Note: Only part of the references are listed.- Effects of Valproic Acid on Proliferation, Apoptosis, Angiogenesis and Metastasis of Ovarian Cancer in Vitro and in Vivo
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- HDAC4 mediates development of hypertension via vascular inflammation in spontaneous hypertensive rats
- (2012) Tatsuya Usui et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
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- (2012) Elizabeth R. Davies et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
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- (2012) Michal Zapotocky et al. CANCER LETTERS
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- (2012) B. K. Ray et al. CANCER RESEARCH
- Inhibition of Histone Deacetylase 3 Protects Beta Cells from Cytokine-Induced Apoptosis
- (2012) Danny Hung-Chieh Chou et al. CHEMISTRY & BIOLOGY
- HDAC Inhibitors Augmented Cell Migration and Metastasis through Induction of PKCs Leading to Identification of Low Toxicity Modalities for Combination Cancer Therapy
- (2012) K.-T. Lin et al. CLINICAL CANCER RESEARCH
- Molecular Pathways: Old Drugs Define New Pathways: Non-Histone Acetylation at the Crossroads of the DNA Damage Response and Autophagy
- (2012) O. A. Botrugno et al. CLINICAL CANCER RESEARCH
- Mechanism of Growth Inhibition of Prostate Cancer Xenografts by Valproic Acid
- (2012) Abhinav Sidana et al. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY
- HDAC2 overexpression confers oncogenic potential to human lung cancer cells by deregulating expression of apoptosis and cell cycle proteins
- (2012) Kwang Hwa Jung et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Apoptosis Induction by SAHA in Cutaneous T-Cell Lymphoma Cells Is Related to Downregulation of c-FLIP and Enhanced TRAIL Signaling
- (2012) Nadya Al-Yacoub et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- P53-dependent antiproliferative and pro-apoptotic effects of trichostatin A (TSA) in glioblastoma cells
- (2012) K. Bajbouj et al. JOURNAL OF NEURO-ONCOLOGY
- Mammalian cells acquire epigenetic hallmarks of human cancer during immortalization
- (2012) Stella Tommasi et al. NUCLEIC ACIDS RESEARCH
- Chromatin acetylation at transcription start sites and vitamin D receptor binding regions relates to effects of 1α,25-dihydroxyvitamin D3 and histone deacetylase inhibitors on gene expression
- (2012) Sabine Seuter et al. NUCLEIC ACIDS RESEARCH
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- (2012) Hong Jian Xie et al. PLoS One
- Interferon Regulatory Factor-8 Is Important for Histone Deacetylase Inhibitor-Mediated Antitumor Activity
- (2012) Debarati Banik et al. PLoS One
- Requirement for the histone deacetylase Hdac3 for the inflammatory gene expression program in macrophages
- (2012) X. Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Radiosensitization by the histone deacetylase inhibitor vorinostat under hypoxia and with capecitabine in experimental colorectal carcinoma
- (2012) Marie Saelen et al. Radiation Oncology
- Vorinostat, an HDAC inhibitor attenuates epidermoid squamous cell carcinoma growth by dampening mTOR signaling pathway in a human xenograft murine model
- (2012) Deepali Kurundkar et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Acetylation Increases EWS-FLI1 DNA Binding and Transcriptional Activity
- (2012) Silke Schlottmann et al. Frontiers in Oncology
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- (2011) Andrew Advani et al. AMERICAN JOURNAL OF PATHOLOGY
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- (2011) Aleksander M Grabiec et al. ANNALS OF THE RHEUMATIC DISEASES
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- (2011) Philipp Baumann et al. BRITISH JOURNAL OF HAEMATOLOGY
- Histone deacetylase inhibitors block nuclear factor-κB-dependent transcription by interfering with RNA polymerase II recruitment
- (2011) Ryohei Furumai et al. CANCER SCIENCE
- Specific Control of Pancreatic Endocrine β- and δ-Cell Mass by Class IIa Histone Deacetylases HDAC4, HDAC5, and HDAC9
- (2011) Olivia Lenoir et al. DIABETES
- Histone Deacetylase Inhibition by Sodium Valproate Regulates Polarization of Macrophage Subsets
- (2011) Chenming Wu et al. DNA AND CELL BIOLOGY
- Inhibition of Glyceroneogenesis by Histone Deacetylase 3 Contributes to Lipodystrophy in Mice with Adipose Tissue Inflammation
- (2011) Jin Zhang et al. ENDOCRINOLOGY
- Histone deacetylase inhibitors in the generation of the anti-tumour immune response
- (2011) Graham R Leggatt et al. IMMUNOLOGY AND CELL BIOLOGY
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- (2011) Zacharoula Konsoula et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
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- (2011) Ji Hye Park et al. INVESTIGATIONAL NEW DRUGS
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- (2011) Kei Suzuki et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Histone deacetylase 1/2 mediates proliferation of renal interstitial fibroblasts and expression of cell cycle proteins
- (2011) Maoyin Pang et al. JOURNAL OF CELLULAR BIOCHEMISTRY
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- (2011) Jay H. Kalin et al. JOURNAL OF MEDICINAL CHEMISTRY
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- (2011) M Gupta et al. LEUKEMIA
- Tubacin suppresses proliferation and induces apoptosis of acute lymphoblastic leukemia cells
- (2011) Grace I. Aldana-Masangkay et al. LEUKEMIA & LYMPHOMA
- Unknown
- (2011) Eli Lewis et al. MOLECULAR MEDICINE
- Unknown
- (2011) Dan Christensen et al. MOLECULAR MEDICINE
- Unknown
- (2011) Antonio Furlan et al. MOLECULAR MEDICINE
- Histone deacetylases as regulators of inflammation and immunity
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- (2010) Maoyin Pang et al. KIDNEY INTERNATIONAL
- Histone deacetylase inhibitors: A new mode for inhibition of cholesterol metabolism
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- (2009) Edwin F. de Zoeten et al. GASTROENTEROLOGY
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- (2009) Laura Susick et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Effect of the immunosuppressant histone deacetylase inhibitor FR276457 in a canine renal transplant model
- (2009) Fumitaka Kinugasa et al. TRANSPLANT IMMUNOLOGY
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- (2008) Christopher M. Reilly et al. JOURNAL OF AUTOIMMUNITY
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- (2008) Fang Liu et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Association of patterns of class I histone deacetylase expression with patient prognosis in gastric cancer: a retrospective analysis
- (2008) Wilko Weichert et al. LANCET ONCOLOGY
- Histone Deacetylase Inhibitors Exert Time-Dependent Effects on Nuclear Factor- B but Consistently Suppress the Expression of Proinflammatory Genes in Human Myometrial Cells
- (2008) T. M. Lindstrom et al. MOLECULAR PHARMACOLOGY
- HDAC inhibitor reduces cytokine storm and facilitates induction of chimerism that reverses lupus in anti-CD3 conditioning regimen
- (2008) N. Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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