Mammalian cells acquire epigenetic hallmarks of human cancer during immortalization

How to become immortal: let MEFs count the ways

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The developing cancer stem-cell model: clinical challenges and opportunities

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The p53 network: cellular and systemic DNA damage responses in aging and cancer

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Insulation of tumor suppressor genes by the nuclear factor CTCF

(2011) Félix Recillas-Targa et al.   Biochemistry and Cell Biology

Musashi1: A stem cell marker no longer in search of a function

(2011) Robert I. Glazer et al.   CELL CYCLE

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(2011) A. M. Deaton et al.   GENES & DEVELOPMENT

Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy

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CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing

(2011) Sanjeev Shukla et al.   NATURE

Cancer epigenetics reaches mainstream oncology

(2011) Manuel Rodríguez-Paredes et al.   NATURE MEDICINE

Non-coding RNAs in human disease

(2011) Manel Esteller   NATURE REVIEWS GENETICS

Senescence and pre-malignancy: How do tumors progress?

(2011) Raya Saab   SEMINARS IN CANCER BIOLOGY

Epigenetic alterations associated with cellular senescence: A barrier against tumorigenesis or a red carpet for cancer?

(2011) Anabelle Decottignies et al.   SEMINARS IN CANCER BIOLOGY

The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression

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Mechanisms and functions of p38 MAPK signalling

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Induced pluripotent stem cells and senescence: learning the biology to improve the technology

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Applications of the human p53 knock-in (Hupki) mouse model for human carcinogen testing

(2010) Ahmad Besaratinia et al.   FASEB JOURNAL

Gene-specific repression of the p53 target gene PUMA via intragenic CTCF-Cohesin binding

(2010) N. P. Gomes et al.   GENES & DEVELOPMENT

Wild-type and Hupki (Human p53 Knock-in) Murine Embryonic Fibroblasts

(2010) Catherine Whibley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Conserved role of intragenic DNA methylation in regulating alternative promoters

(2010) Alika K. Maunakea et al.   NATURE

Principles and challenges of genome-wide DNA methylation analysis

(2010) Peter W. Laird   NATURE REVIEWS GENETICS

The role of signaling pathways in the development and treatment of hepatocellular carcinoma

(2010) S Whittaker et al.   ONCOGENE

A Human-Like Senescence-Associated Secretory Phenotype Is Conserved in Mouse Cells Dependent on Physiological Oxygen

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Investigating the Epigenetic Effects of a Prototype Smoke-Derived Carcinogen in Human Cells

(2010) Stella Tommasi et al.   PLoS One

Distinct histone modifications in stem cell lines and tissue lineages from the early mouse embryo

(2010) P. J. Rugg-Gunn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Cellular Senescence: Molecular Mechanisms, In Vivo Significance, and Redox Considerations

(2008) Michael Muller   ANTIOXIDANTS & REDOX SIGNALING

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols

DNA methylation landscapes: provocative insights from epigenomics

(2008) Miho M. Suzuki et al.   NATURE REVIEWS GENETICS

Critical pathways in cellular senescence and immortalization revealed by gene expression profiling

(2008) A L Fridman et al.   ONCOGENE

A Novel CpG Island Set Identifies Tissue-Specific Methylation at Developmental Gene Loci

(2008) Robert Illingworth et al.   PLOS BIOLOGY

Genomewide Analysis of PRC1 and PRC2 Occupancy Identifies Two Classes of Bivalent Domains

(2008) Manching Ku et al.   PLoS Genetics