Small-Molecule NOX Inhibitors: ROS-Generating NADPH Oxidases as Therapeutic Targets

Endothelial cell barrier protection by simvastatin: GTPase regulation and NADPH oxidase inhibition

(2008) Weiguo Chen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The molecular sources of reactive oxygen species in hypertension

(2008) Paolo Puddu et al.   BLOOD PRESSURE

Platelet-derived growth factor BB stimulates vasculogenesis of embryonic stem cell-derived endothelial cells by calcium-mediated generation of reactive oxygen species

(2008) S. Lange et al.   CARDIOVASCULAR RESEARCH

Classical Inhibitors of NOX NAD(P)H Oxidases Are Not Specific

(2008) Elisabetta Aldieri et al.   CURRENT DRUG METABOLISM

Inhibition of NADPH oxidase-related oxidative stress-triggered signaling by honokiol suppresses high glucose-induced human endothelial cell apoptosis

(2008) Meei Ling Sheu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Is Cardiac Hypertrophy in Spontaneously Hypertensive Rats the Cause or the Consequence of Oxidative Stress?

(2008) María Cecilia ÁLVAREZ et al.   HYPERTENSION RESEARCH

Upregulation of the NADPH oxidase NOX4 by TGF-beta in hepatocytes is required for its pro-apoptotic activity

(2008) Irene Carmona-Cuenca et al.   JOURNAL OF HEPATOLOGY

Apocynin: Molecular Aptitudes

(2008) J. Stefanska et al.   MEDIATORS OF INFLAMMATION

Apocynin improves outcome in experimental stroke with a narrow dose range

(2008) X.N. Tang et al.   NEUROSCIENCE

NADPH oxidases in the vasculature: Molecular features, roles in disease and pharmacological inhibition

(2008) Stavros Selemidis et al.   PHARMACOLOGY & THERAPEUTICS

Hyperinflammation in chronic granulomatous disease and anti-inflammatory role of the phagocyte NADPH oxidase

(2008) Michela G. Schäppi et al.   Seminars in Immunopathology

NOX enzymes as novel targets for drug development

(2008) J. David Lambeth et al.   Seminars in Immunopathology

Excess Salt Causes Cerebral Neuronal Apoptosis and Inflammation in Stroke-Prone Hypertensive Rats Through Angiotensin II-Induced NADPH Oxidase Activation

(2008) Eiichiro Yamamoto et al.   STROKE

Protective effects of apocynin and allopurinol on ischemia/reperfusion-induced liver injury in mice

(2008) Ping-Guo Liu et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Apocynin, NADPH Oxidase, and Vascular Cells

(2007) Rhian M. Touyz   HYPERTENSION

Apocynin Is Not an Inhibitor of Vascular NADPH Oxidases but an Antioxidant

(2007) Sabine Heumüller et al.   HYPERTENSION

Bioavailability of apocynin through its conversion to glycoconjugate but not to diapocynin

(2007) Qun Wang et al.   PHYTOMEDICINE

The NADPH oxidase inhibitor apocynin induces nitric oxide synthesis via oxidative stress

(2007) Chiara Riganti et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Inhibition of superoxide anion and elastase release in human neutrophils by 3′-isopropoxychalcone via a cAMP-dependent pathway

(2006) Tsong-Long Hwang et al.   BRITISH JOURNAL OF PHARMACOLOGY