Renin–angiotensin system blockade: a novel therapeutic approach in chronic obstructive pulmonary disease

Does physical inactivity cause chronic obstructive pulmonary disease?

(2015) Nicholas S. Hopkinson et al.   CLINICAL SCIENCE

Chronic obstructive pulmonary disease: consequences beyond the lung

(2013) D. Shrikrishna et al.   CLINICAL MEDICINE

Combined Pulmonary Fibrosis and Emphysema Syndrome

(2012) Matthew D. Jankowich et al.   CHEST

Quadriceps wasting and physical inactivity in patients with COPD

(2012) Dinesh Shrikrishna et al.   EUROPEAN RESPIRATORY JOURNAL

The chronic bronchitis phenotype in subjects with and without COPD: the PLATINO study

(2012) Maria Montes de Oca et al.   EUROPEAN RESPIRATORY JOURNAL

Physical Exercise as an Epigenetic Modulator

(2012) Fabian Sanchis-Gomar et al.   JOURNAL OF STRENGTH AND CONDITIONING RESEARCH

Angiotensin II Infusion Induces Marked Diaphragmatic Skeletal Muscle Atrophy

(2012) Bashir M. Rezk et al.   PLoS One

The pathogenesis of COPD and IPF: Distinct horns of the same devil?

(2012) Marco Chilosi et al.   RESPIRATORY RESEARCH

Regulation of alveolar epithelial cell survival by the ACE-2/angiotensin 1–7/Mas axis

(2011) Bruce D. Uhal et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

LPS-Stimulated Cytokine Production in Type I Cells Is Modulated by the Renin–Angiotensin System

(2011) Mandi H. Wong et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Systemic Manifestations of COPD

(2011) Yvonne Nussbaumer-Ochsner et al.   CHEST

Local Renin-Angiotensin II Systems, Angiotensin-Converting Enzyme and its Homologue ACE2: Their Potential Role in the Pathogenesis of Chronic Obstructive Pulmonary Diseases, Pulmonary Hypertension and Acute Respiratory Distress Syndrome

(2011) A. Kaparianos et al.   CURRENT MEDICINAL CHEMISTRY

ACE2, a promising therapeutic target for pulmonary hypertension

(2011) Vinayak Shenoy et al.   CURRENT OPINION IN PHARMACOLOGY

Pulmonary hypertension in advanced chronic obstructive pulmonary disease

(2011) Randy Orr et al.   CURRENT OPINION IN PULMONARY MEDICINE

Renin is an angiotensin-independent profibrotic mediator: role in pulmonary fibrosis

(2011) E. Montes et al.   EUROPEAN RESPIRATORY JOURNAL

Angiotensin signalling in pulmonary fibrosis

(2011) Bruce D. Uhal et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Angiotensin receptor blockade attenuates cigarette smoke–induced lung injury and rescues lung architecture in mice

(2011) Megan Podowski et al.   JOURNAL OF CLINICAL INVESTIGATION

Controversies in treatment of chronic obstructive pulmonary disease

(2011) Klaus F Rabe et al.   LANCET

Enalapril treatment discloses an early role of angiotensin II in inflammation- and oxidative stress-related muscle damage in dystrophic mdx mice

(2011) Anna Cozzoli et al.   PHARMACOLOGICAL RESEARCH

Cardiovascular mechanisms of death in severe COPD exacerbation: time to think and act beyond guidelines

(2011) L. M. Fabbri et al.   THORAX

Biochemical markers of cardiac dysfunction predict mortality in acute exacerbations of COPD

(2011) C. L. Chang et al.   THORAX

Elevated high-sensitivity cardiac troponin T is associated with increased mortality after acute exacerbation of chronic obstructive pulmonary disease

(2011) A. D. Hoiseth et al.   THORAX

Gene expression networks in COPD: microRNA and mRNA regulation

(2011) Michael E Ezzie et al.   THORAX

The COPD assessment test (CAT): response to pulmonary rehabilitation. A multicentre, prospective study

(2011) J. W. Dodd et al.   THORAX

Downregulation of the serum response factor/miR-1 axis in the quadriceps of patients with COPD

(2011) Amy Lewis et al.   THORAX

Chronic Obstructive Pulmonary Disease Phenotypes

(2010) MeiLan K. Han et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Monocyte Chemoattractant Protein–1 Released from Alveolar Macrophages Mediates the Systemic Inflammation of Acute Alveolar Hypoxia

(2010) Jie Chao et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Effects of Estradiol, Angiotensin-Converting Enzyme Inhibitor and Exercise Training on Exercise Capacity and Skeletal Muscle in Old Female Rats

(2010) Qi Guo et al.   CLINICAL AND EXPERIMENTAL HYPERTENSION

Targeting the Vasoprotective Axis of the Renin-Angiotensin System: A Novel Strategic Approach to Pulmonary Hypertensive Therapy

(2010) Chastity N. Bradford et al.   CURRENT HYPERTENSION REPORTS

Angiotensin II revisited: new roles in inflammation, immunology and aging

(2010) Ariela Benigni et al.   EMBO Molecular Medicine

ACE I/D and ACTN3 R/X polymorphisms and muscle function and muscularity of older Caucasian men

(2010) Tracey McCauley et al.   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

Quadriceps myostatin expression in COPD

(2010) W. D-C. Man et al.   EUROPEAN RESPIRATORY JOURNAL

Effect of pulmonary rehabilitation on muscle remodelling in cachectic patients with COPD

(2010) I. Vogiatzis et al.   EUROPEAN RESPIRATORY JOURNAL

Angiotensin II receptor blocker telmisartan enhances running endurance of skeletal muscle through activation of the PPAR-δ/AMPK pathway

(2010) Xiaoli Feng et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Effect of enalapril on exercise cardiopulmonary performance in chronic obstructive pulmonary disease: A pilot study

(2010) Fabiano Di Marco et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Local and systemic effects of angiotensin receptor blockade in an emphysema mouse model

(2010) Tobias Raupach et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Sub-clinical left and right ventricular dysfunction in patients with COPD

(2010) Ramsey Sabit et al.   RESPIRATORY MEDICINE

Categorization and impact of pulmonary hypertension in patients with advanced COPD

(2010) Michael J. Cuttica et al.   RESPIRATORY MEDICINE

Evidence for Angiotensin-converting Enzyme 2 as a Therapeutic Target for the Prevention of Pulmonary Hypertension

(2009) Anderson J. Ferreira et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Cellular Markers of Muscle Atrophy in Chronic Obstructive Pulmonary Disease

(2009) Pamela J. Plant et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Skeletal muscle dysfunction in COPD: clinical and laboratory observations

(2009) William D.-C. Man et al.   CLINICAL SCIENCE

Progression of chronic obstructive pulmonary disease: impact of inflammation, comorbidities and therapeutic intervention

(2009) Robert A. Stockley   CURRENT MEDICAL RESEARCH AND OPINION

Cardiovascular protection by angiotensin-converting enzyme inhibition

(2009) R. Ferrari   EUROPEAN HEART JOURNAL SUPPLEMENTS

Systemic manifestations and comorbidities of COPD

(2009) P. J. Barnes et al.   EUROPEAN RESPIRATORY JOURNAL

The prevalence of quadriceps weakness in COPD and the relationship with disease severity

(2009) J. M. Seymour et al.   EUROPEAN RESPIRATORY JOURNAL

Prevention of Pulmonary Hypertension by Angiotensin-Converting Enzyme 2 Gene Transfer

(2009) Yoriko Yamazato et al.   HYPERTENSION

Reinventing the ACE inhibitors: some old and new implications of ACE inhibition

(2009) Kashif Hanif et al.   HYPERTENSION RESEARCH

Co-existence of COPD and left ventricular dysfunction in vascular surgery patients

(2009) Willem-Jan Flu et al.   RESPIRATORY MEDICINE

A phase I/IItrial of MYO-029 in adult subjects with muscular dystrophy

(2008) Kathryn R. Wagner et al.   ANNALS OF NEUROLOGY

Angiotensin inhibition stimulates PPARγ and the release of visfatin

(2008) A. Storka et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1α

(2008) Zoltan Arany et al.   NATURE

Fiber Type-Specific Nitric Oxide Protects Oxidative Myofibers against Cachectic Stimuli

(2008) Zengli Yu et al.   PLoS One