The Mechanisms and Applications of T Cell Vaccination for Autoimmune Diseases: a Comprehensive Review

Homeostasis and function of regulatory T cells (Tregs)in vivo: lessons from TCR-transgenic Tregs

(2014) Kesley Attridge et al.   IMMUNOLOGICAL REVIEWS

Activation of benign autoimmunity as both tumor and autoimmune disease immunotherapy: A comprehensive review

(2014) Irun R. Cohen   JOURNAL OF AUTOIMMUNITY

Novel approaches to the development of targeted therapeutic agents for systemic lupus erythematosus

(2014) Zev Sthoeger et al.   JOURNAL OF AUTOIMMUNITY

Conservation of Pathogenic TCR Homology across Class II Restrictions in Anti-Ribonucleoprotein Autoimmunity: Extended Efficacy of T Cell Vaccine Therapy

(2014) Y. Zang et al.   JOURNAL OF IMMUNOLOGY

Systemic lupus erythematosus and lupus nephritis

(2014) Toli Koutsokeras et al.   NATURE REVIEWS DRUG DISCOVERY

A69: Lupus Nephritis and Autoantibody Characteristics of a Single Center Cohort of Male Pediatric SLE Patients

(2014) Scott E. Wenderfer et al.   Arthritis & Rheumatology

Early detection of thrombin activity in neuroinflammatory disease

(2013) Dimitrios Davalos et al.   ANNALS OF NEUROLOGY

Treg Vaccination in Autoimmune Type 1 Diabetes

(2013) Isabelle Serr et al.   BIODRUGS

Antigen-Based Vaccination and Prevention of Type 1 Diabetes

(2013) Leonard C. Harrison et al.   Current Diabetes Reports

Are Transient Environmental Agents Involved in the Aetiology of Primary Biliary Cirrhosis?

(2013) Richard J.Q. McNally   DISEASE MARKERS

Using EAE to better understand principles of immune function and autoimmune pathology

(2013) Manu Rangachari et al.   JOURNAL OF AUTOIMMUNITY

The Role of CD8+ T Cells and Their Local Interaction with CD4+ T Cells in Myelin Oligodendrocyte Glycoprotein35-55-Induced Experimental Autoimmune Encephalomyelitis

(2013) T. Leuenberger et al.   JOURNAL OF IMMUNOLOGY

Systemic lupus erythematosus and other autoimmune rheumatic diseases: challenges to treatment

(2013) Grainne Murphy et al.   LANCET

Immunopathogenic mechanisms of systemic autoimmune disease

(2013) Marie Wahren-Herlenius et al.   LANCET

Challenges and approaches for the development of safer immunomodulatory biologics

(2013) Jean G. Sathish et al.   NATURE REVIEWS DRUG DISCOVERY

Clinical targeting of the TNF and TNFR superfamilies

(2013) Michael Croft et al.   NATURE REVIEWS DRUG DISCOVERY

The spectrum of MOG autoantibody-associated demyelinating diseases

(2013) Markus Reindl et al.   Nature Reviews Neurology

Autoantibodies and SLE—the threshold for disease

(2013) Nancy J. Olsen et al.   Nature Reviews Rheumatology

Vaccination with Flt3L-induced CD8α+ dendritic cells prevents CD4+ T helper cell-mediated experimental autoimmune myocarditis

(2013) Alan Valaperti et al.   VACCINE

Treg inducing adjuvants for therapeutic vaccination against chronic inflammatory diseases

(2013) Chantal Keijzer   Frontiers in Immunology

Effect of Triptolide on T-Cell Receptor Beta Variable Gene mRNA Expression in Rats With Collagen-Induced Arthritis

(2012) Jixi Wang et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

C57BL/6 mice need MHC class II Aq to develop collagen-induced arthritis dependent on autoreactive T cells

(2012) Johan Bäcklund et al.   ANNALS OF THE RHEUMATIC DISEASES

Glatiramer acetate ameliorates inflammatory bowel disease in mice through the induction of Qa-1-restricted CD8+regulatory cells

(2012) Yunliang Yao et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Antimitochondrial antibody heterogeneity and the xenobiotic etiology of primary biliary cirrhosis

(2012) Richy C.Y. Chen et al.   HEPATOLOGY

Regulatory NK cells in autoimmune disease

(2012) Zhigang Tian et al.   JOURNAL OF AUTOIMMUNITY

Heritability versus the role of the environment in autoimmunity

(2012) Carlo Selmi et al.   JOURNAL OF AUTOIMMUNITY

Rheumatoid arthritis: From autoimmunity to synovitis and joint destruction

(2012) Marie-Christophe Boissier et al.   JOURNAL OF AUTOIMMUNITY

CD8+ Regulatory T Cells Induced by T Cell Vaccination Protect Against Autoimmune Nephritis

(2012) Y. M. Wang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

T Cell Vaccination Benefits Relapsing Progressive Multiple Sclerosis Patients: A Randomized, Double-Blind Clinical Trial

(2012) Dimitrios Karussis et al.   PLoS One

T-cell vaccination leads to suppression of intrapancreatic Th17 cells through Stat3-mediated RORγt inhibition in autoimmune diabetes

(2011) Min Wang et al.   CELL RESEARCH

Autoimmunity and Environment: Am I at risk?

(2011) Daniel Smyk et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

CD4 T cells and their antigens in the pathogenesis of autoimmune diabetes

(2011) Kathryn Haskins et al.   CURRENT OPINION IN IMMUNOLOGY

Tovaxin for multiple sclerosis

(2011) Victor M Rivera   EXPERT OPINION ON BIOLOGICAL THERAPY

Twin studies in autoimmune disease: Genetics, gender and environment

(2011) Dimitrios P. Bogdanos et al.   JOURNAL OF AUTOIMMUNITY

Autoantibodies in systemic lupus erythematosus: comparison of historical and current assessment of seropositivity

(2011) A Ippolito et al.   LUPUS

A randomized clinical trial of autologous T-cell therapy in multiple sclerosis: subset analysis and implications for trial design

(2011) Edward Fox et al.   Multiple Sclerosis Journal

‘Multi-Epitope-Targeted’ Immune-Specific Therapy for a Multiple Sclerosis-Like Disease via Engineered Multi-Epitope Protein Is Superior to Peptides

(2011) Nathali Kaushansky et al.   PLoS One

T cell vaccination therapy in an induced model of anti-RNP autoimmune glomerulonephritis

(2010) Sapna Trivedi et al.   CLINICAL IMMUNOLOGY

T cell vaccination induces the elimination of EAE effector T cells: Analysis using GFP-transduced, encephalitogenic T cells

(2010) Ilan Volovitz et al.   JOURNAL OF AUTOIMMUNITY

Rheumatoid arthritis

(2010) David L Scott et al.   LANCET

Inhibition of follicular T-helper cells by CD8+ regulatory T cells is essential for self tolerance

(2010) Hye-Jung Kim et al.   NATURE

Clonal expansions in selected TCR BV families of rheumatoid arthritis patients are reduced by treatment with the TNFα inhibitors etanercept and infliximab

(2010) Matthias Pierer et al.   RHEUMATOLOGY INTERNATIONAL

Silencing Nogo-A promotes functional recovery in demyelinating disease

(2009) Yuhong Yang et al.   ANNALS OF NEUROLOGY

Tissue targeting of anti-RNP autoimmunity: Effects of T cells and myeloid dendritic cells in a murine model

(2009) Eric L. Greidinger et al.   ARTHRITIS AND RHEUMATISM

The myelin-associated oligodendrocytic basic protein (MOBP) as a relevant primary target autoantigen in multiple sclerosis

(2009) Nathali Kaushansky et al.   AUTOIMMUNITY REVIEWS

Autologous attenuated T-cell vaccine (Tovaxin®) dose escalation in multiple sclerosis relapsing–remitting and secondary progressive patients nonresponsive to approved immunomodulatory therapies

(2009) B. Loftus et al.   CLINICAL IMMUNOLOGY

Regulatory T cells and inhibitory cytokines in autoimmunity

(2009) Maria Bettini et al.   CURRENT OPINION IN IMMUNOLOGY

Vaccination with autoreactive CD4+Th1 clones in lupus-prone MRL/Mp-Faslpr/lpr mice

(2009) Takao Fujii et al.   JOURNAL OF AUTOIMMUNITY

Inflammatory clearance of apoptotic remnants in systemic lupus erythematosus (SLE)

(2008) C. Janko et al.   AUTOIMMUNITY REVIEWS

Autoimmune mechanisms in type 1 diabetes

(2008) Mikael Knip et al.   AUTOIMMUNITY REVIEWS

HSP60 as a Target of Anti-Ergotypic Regulatory T Cells

(2008) Francisco J. Quintana et al.   PLoS One

Revival of CD8+ Treg–mediated suppression

(2008) Trevor R.F. Smith et al.   TRENDS IN IMMUNOLOGY