Journal
CLINICAL PHARMACOLOGY & THERAPEUTICS
Volume 95, Issue 4, Pages 341-346Publisher
WILEY
DOI: 10.1038/clpt.2014.15
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Cancer chemotherapy has transitioned from the use of cytotoxic drugs to the era of agents with an apparent selectivity for a cancer-specific target. The past decade has provided evidence that therapy with such agents can be curative in subsets of patients. It is anticipated that incorporation of pharmacological principles for novel therapeutics will result in further refinement of outcome measures as well as the discovery of new treatment modalities for multiple malignant diseases.
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