A Screening Study of Drug–Drug Interactions in Cerivastatin Users: An Adverse Effect of Clopidogrel

Evaluation of CYP2C8 Inhibition In Vitro: Utility of Montelukast as a Selective CYP2C8 Probe Substrate

(2011) B. M. VandenBrink et al.   DRUG METABOLISM AND DISPOSITION

Cerivastatin, genetic variants, and the risk of rhabdomyolysis

(2011) Kristin D. Marciante et al.   Pharmacogenetics and Genomics

Participation of CYP2C8 and CYP3A4 in the N-demethylation of imatinib in human hepatic microsomes

(2010) Noelia Nebot et al.   BRITISH JOURNAL OF PHARMACOLOGY

Gemfibrozil Markedly Increases the Plasma Concentrations of Montelukast: A Previously Unrecognized Role for CYP2C8 in the Metabolism of Montelukast

(2010) T Karonen et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Are Circulating Metabolites Important in Drug–Drug Interactions?: Quantitative Analysis of Risk Prediction and Inhibitory Potency

(2010) C K Yeung et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Paraoxonase-1 is a major determinant of clopidogrel efficacy

(2010) Heleen J Bouman et al.   NATURE MEDICINE

Membrane transporters in drug development

(2010)   NATURE REVIEWS DRUG DISCOVERY

Cerivastatin in vitro metabolism by CYP2C8 variants found in patients experiencing rhabdomyolysis

(2010) Rüdiger Kaspera et al.   Pharmacogenetics and Genomics

Metabolism and Disposition of the Thienopyridine Antiplatelet Drugs Ticlopidine, Clopidogrel, and Prasugrel in Humans

(2009) Nagy A. Farid et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Rhabdomyolysis reports show interaction between simvastatin and CYP3A4 inhibitors

(2009) Christopher Rowan et al.   PHARMACOEPIDEMIOLOGY AND DRUG SAFETY

Comparison of mechanism-based inhibition of human cytochrome P450 2C19 by ticlopidine, clopidogrel, and prasugrel

(2009) Y. Nishiya et al.   XENOBIOTICA

Integrated in Vitro Analysis for the in Vivo Prediction of Cytochrome P450-Mediated Drug-Drug Interactions

(2008) D. F. McGinnity et al.   DRUG METABOLISM AND DISPOSITION

PREDICTION OF DRUG-DRUG INTERACTIONS FROM IN VITRO INDUCTION DATA: Application of the Relative Induction Score Approach Using Cryopreserved Human Hepatocytes

(2008) O. A. Fahmi et al.   DRUG METABOLISM AND DISPOSITION