In Vivo CYP3A4 Activity, CYP3A5 Genotype, and Hematocrit Predict Tacrolimus Dose Requirements and Clearance in Renal Transplant Patients

In Vivo CYP3A Activity Is Significantly Lower in Cyclosporine-Treated as Compared With Tacrolimus-Treated Renal Allograft Recipients

(2011) H de Jonge et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Novel Polymorphisms Associated With Tacrolimus Trough Concentrations: Results From a Multicenter Kidney Transplant Consortium

(2011) Pamala A. Jacobson et al.   TRANSPLANTATION

A Phase III Study of Belatacept-based Immunosuppression Regimens versus Cyclosporine in Renal Transplant Recipients (BENEFIT Study)

(2010) F. Vincenti et al.   AMERICAN JOURNAL OF TRANSPLANTATION

A highly sensitive liquid chromatography tandem mass spectrometry method for simultaneous quantification of midazolam, 1′-hydroxymidazolam and 4-hydroxymidazolam in human plasma

(2010) Henriette de Loor et al.   BIOMEDICAL CHROMATOGRAPHY

Multi-center evaluation of a commercial Kit for tacrolimus determination by LC/MS/MS

(2010) Kimberly L. Napoli et al.   CLINICAL BIOCHEMISTRY

Effect of CYP3A and ABCB1 Single Nucleotide Polymorphisms on the Pharmacokinetics and Pharmacodynamics of Calcineurin Inhibitors: Part II

(2010) Christine E. Staatz et al.   CLINICAL PHARMACOKINETICS

Effect of CYP3A and ABCB1 Single Nucleotide Polymorphisms on the Pharmacokinetics and Pharmacodynamics of Calcineurin Inhibitors: Part I

(2010) Christine E. Staatz et al.   CLINICAL PHARMACOKINETICS

Tacrolimus Dose Requirements and CYP3A5 Genotype and the Development of Calcineurin Inhibitor-Associated Nephrotoxicity in Renal Allograft Recipients

(2010) Dirk R J Kuypers et al.   THERAPEUTIC DRUG MONITORING

Belatacept-Based Regimens Versus a Cyclosporine A-Based Regimen in Kidney Transplant Recipients: 2-Year Results From the BENEFIT and BENEFIT-EXT Studies

(2010) Christian P. Larsen et al.   TRANSPLANTATION

The Drug Transporter−Metabolism Alliance: Uncovering and Defining the Interplay

(2009) Leslie Z. Benet   MOLECULAR PHARMACEUTICS

Association of genotypes of the CYP3A cluster with midazolam disposition in vivo

(2009) J Miao et al.   PHARMACOGENOMICS JOURNAL

Opportunities to Optimize Tacrolimus Therapy in Solid Organ Transplantation: Report of the European Consensus Conference

(2009) Pierre Wallemacq et al.   THERAPEUTIC DRUG MONITORING

New Insights Into the Pharmacokinetics and Pharmacodynamics of the Calcineurin Inhibitors and Mycophenolic Acid: Possible Consequences for Therapeutic Drug Monitoring in Solid Organ Transplantation

(2009) Hylke de Jonge et al.   THERAPEUTIC DRUG MONITORING

Early clinical assessment of glucose metabolism in renal allograft recipients: diagnosis and prediction of post-transplant diabetes mellitus (PTDM)

(2008) D. R. J. Kuypers et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

CYP3A5 genotype is not associated with a higher risk of acute rejection in tacrolimus-treated renal transplant recipients

(2008) Dennis A. Hesselink et al.   Pharmacogenetics and Genomics

Pharmacogenetics in solid organ transplantation: current status and future directions

(2007) Hylke de Jonge et al.   Transplantation Reviews