The Systems Biology Approach to Drug Development: Application to Toxicity Assessment of Cardiac Drugs

Arrhythmic risk biomarkers for the assessment of drug cardiotoxicity: from experiments to computer simulations

(2012) A. Corrias et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES

Impact of ionic current variability on human ventricular cellular electrophysiology

(2009) Lucía Romero et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Development of an anatomically detailed MRI-derived rabbit ventricular model and assessment of its impact on simulations of electrophysiological function

(2009) Martin J. Bishop et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Parameter Sensitivity Analysis in Electrophysiological Models Using Multivariable Regression

(2009) Eric A. Sobie   BIOPHYSICAL JOURNAL

Chaste: A test-driven approach to software development for biological modelling

(2009) Joe Pitt-Francis et al.   COMPUTER PHYSICS COMMUNICATIONS

A BEAUTIFUL lesson--ivabradine protects from ischaemia, but not from heart failure: through heart rate reduction or more?

(2009) G. Heusch   EUROPEAN HEART JOURNAL

Towards predictive modelling of the electrophysiology of the heart

(2009) Edward Vigmond et al.   EXPERIMENTAL PHYSIOLOGY

Generation of histo-anatomically representative models of the individual heart: tools and application

(2009) G. Plank et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES

Calsequestrin-Mediated Mechanism for Cellular Calcium Transient Alternans

(2008) Juan G. Restrepo et al.   BIOPHYSICAL JOURNAL

Feedback Remodeling of Cardiac Potassium Current Expression

(2008) Ling Xiao et al.   CIRCULATION

Sex, Age, and Regional Differences in L-Type Calcium Current Are Important Determinants of Arrhythmia Phenotype in Rabbit Hearts With Drug-Induced Long QT Type 2

(2008) Carl Sims et al.   CIRCULATION RESEARCH

Multiscale modelling of drug-induced effects on cardiac electrophysiological activity

(2008) T. Brennan et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Computational Models of the Heart and Their Use in Assessing the Actions of Drugs

(2008) Denis Noble   JOURNAL OF PHARMACOLOGICAL SCIENCES