Article
Dentistry, Oral Surgery & Medicine
Huimin Nie, Yantai Tang, Yan Yang, Weijie Wu, Wenjuan Zhou, Zhonghao Liu
Summary: This study aimed to investigate the effect of a two-piece abutment design on the stress in the implant components and surrounding bone, as well as its influence on microgap formation. The results showed that the two-piece abutment design had no significant effect on peri-implant bone stress, but the mechanical effects associated with the base and screws should be noted. Furthermore, the two-piece abutment design had no advantage in eliminating the microgap.
Article
Dentistry, Oral Surgery & Medicine
Cristina Carral, Juan Flores-Guillen, Elena Figuero, Daniel Rodrigo, Ignacio Sanz-Sanchez, Juan Carlos Llodra, Manuel Bravo, Raul G. Caffesse, Nuria Vallcorba, Adrian Guerrero, Antonio Bujaldon, David Herrera
Summary: This study evaluated radiographic bone level (RxBL) at dental implants in Spain, finding significant associations between RxBL and clinical output variables as well as potential predictor variables such as smoking habits, implant diameter, years of follow-up, and type of prosthesis. Peri-implant RxBL ranged from 0 to 13.17 mm, demonstrating its importance in implant success and maintenance.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2021)
Article
Chemistry, Physical
Takashi Matsuoka, Tamaki Nakano, Satoshi Yamaguchi, Shinji Ono, Shota Watanabe, Takumi Sato, Hirofumi Yatani
Summary: This study investigated the mechanical influences of the implant-abutment connection type and inter-implant distance on the inter-implant bone using three-dimensional finite element analysis. The results showed that a CC implant is advantageous for maintenance of the inter-implant bone, and regardless of the connection type, the stress of the inter-implant bone increases as the inter-implant distance decreases.
Article
Chemistry, Physical
Mahdis Parsafar, Sayed Khatiboleslam Sadrnezhaad, Nahid Hassanzadeh Nemati
Summary: The increasing number of spine diseases and surgeries has led to advancements in spine equipment and implants. Selecting the right type of implant is crucial due to the unique anatomy of the spine. Nitinol, a thermoelastic NiTi alloy, has been found to possess properties like high biocompatibility and superelasticity, making it suitable for spinal implants.
JOURNAL OF ALLOYS AND COMPOUNDS
(2023)
Article
Dentistry, Oral Surgery & Medicine
Helena Francisco, Gary Finelle, Fabien Bornert, Rebecca Sandgren, Valentin Herber, Nils Warfving, Benjamin E. Pippenger
Summary: In this study, the influence of transgingival compared with submerged healing on peri-implant bone maintenance around a novel implant in minipigs was evaluated. The results showed no significant differences between transgingival and submerged healing in most parameters, except for more bone formation on the buccal aspect in the transgingival healing group. Both groups demonstrated an increase in crestal bone height during the healing period. Loaded and unloaded implants displayed comparable levels of osseointegration and equivalent marginal bone levels.
CLINICAL ORAL INVESTIGATIONS
(2021)
Article
Engineering, Biomedical
Aimen Bagegni, Simon Zabler, Katja Nelson, Alexander Rack, Benedikt C. Spies, Kirstin Vach, Ralf Kohal
Summary: This study evaluated the effect of dynamic-loading on the microgap of the internal microgap of the IAC when different supratructure heights are applied. The results showed that regardless of the crown height, the microgap between the abutment and implant systematically decreased after loading in both butt-joint and internal-conical connections.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2021)
Article
Dentistry, Oral Surgery & Medicine
Sangmyeong Tak, Gunwoo Noh, Yuwon Jeong, Hyeonjong Lee
Summary: Prosthesis loading force plays a crucial role in dental implant survival. Improper distribution of occlusal forces can generate lateral torque and lead to high stress on surrounding tissues, even with adequate osseointegration. The direction and shape of the occlusal surface affect the stress values of implant prostheses. Computer-aided design software can be used to visualize and analyze the average vectors from each occlusal contact point, allowing for modifications in the occlusal surface design to optimize prosthesis function.
JOURNAL OF PROSTHETIC DENTISTRY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Pedro F. Fernandes, Liliana Grenho, Maria H. Fernandes, Pedro S. Gomes, Joao C. Sampaio-Fernandes
Summary: The purpose of this study was to characterize the microgap and bacterial microleakage at the implant-prosthetic abutment interface and evaluate the effectiveness of a sealing agent. Scanning electron microscopy and bacterial colonization experiments were conducted, and it was found that despite a small microgap, bacterial microleakage still occurred in the tested system. However, the use of a silicone-based sealing agent effectively prevented bacterial leakage.
JOURNAL OF PROSTHETIC DENTISTRY
(2023)
Article
Multidisciplinary Sciences
Jia-Wen Wang, Kai Yu, Man Li, Jun Wu, Jie Wang, Chang-Wu Wan, Chao-Lun Xiao, Bing Xia, Jiang Huang
Summary: The nanoindentation technique was applied to analyze micro-mechanical properties of different structures of human cadaveric skull and cranial suture, showing significant differences in hardness and modulus of elasticity among different age groups.
SCIENTIFIC REPORTS
(2022)
Article
Engineering, Biomedical
Shi Yin, Wenjie Zhang, Yanmei Tang, Guangzheng Yang, Xiaolin Wu, Sihan Lin, Xuanyong Liu, Huiliang Cao, Xinquan Jiang
Summary: The biomaterial with a micropore-channel structure, developed using 3D printing technology, showed promising potential in future clinical applications for dental implants in a canine surgical model, facilitating bone mesenchymal stem cell proliferation and differentiation.
BIOACTIVE MATERIALS
(2021)
Article
Biotechnology & Applied Microbiology
Lingling Zheng, Chao Wang, Min Hu, Antonio Apicella, Lizhen Wang, Ming Zhang, Yubo Fan
Summary: This study proposes a novel 3D titanium lattice-like implant for mandibular injuries based on a simulation model. The implant is designed and optimized using a biomechanical/mechanobiological approach to meet specific patient requirements. The results show that the implant can be improved through topological optimization, and customized implants fabricated using metal additive manufacturing technology have excellent biomechanical and mechanobiological properties, promoting new bone regeneration.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Multidisciplinary Sciences
Yizhou Zhu, Hang Liang, Xiangmei Liu, Jun Wu, Cao Yang, Tak Man Wong, Kenny Y. H. Kwan, Kenneth M. C. Cheung, Shuilin Wu, Kelvin W. K. Yeung
Summary: The study showed that reducing the scale of honeycomb-like TiO2 structures can activate anti-inflammatory macrophage phenotype, promoting osteogenesis. Among different scales, the 90-nanometer sample demonstrated the most effective outcomes in both in vitro cell culture and in vivo implantation experiments.
Article
Dentistry, Oral Surgery & Medicine
Carlos Guillermo Benitez Silva, Vitor Marques Sapata, Alexandre Hugo Llanos, Marcelo Munhoes Romano, Ronald Ernst Jung, Christoph Hans Franz Hammerle, Joao Batista Cesar-Neto, Claudio Mendes Pannuti, Giuseppe Alexandre Romito
Summary: In the aesthetic zone, tissue changes following alveolar ridge preservation (ARP) treatment using different biomaterials showed no significant differences in mid-facial mucosal level and marginal bone loss 1 year after implant restoration. However, soft tissue thickness at 3 and 5mm below the mucosal margin significantly differed between groups at pre-crown placement stage. After crown insertion, tissue stability was predictable regardless of biomaterial used.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2022)
Article
Dentistry, Oral Surgery & Medicine
Peter Gehrke, Simon Burg, Ulrike Peters, Thomas Beikler, Carsten Fischer, Frank Rupp, Ernst Schweizer, Paul Weigl, Robert Sader, Ralf Smeets, Sogand Schaefer
Summary: This study examined the microgap formation and bacterial leakage at the Acuris conometric restorative interface of three different implant abutment systems, finding no microbial leakage but small punctate microgaps at the apical aspect of the conometric junction and cement gaps at the crown-coping interface within clinically acceptable limits.
CLINICAL ORAL INVESTIGATIONS
(2022)
Article
Chemistry, Physical
Omer Cohen, Dieter D. Bosshardt, Evegeny Weinberg, Gil Slutzkey, Ofer Moses
Summary: The study found that implant neck design and drilling protocol did not significantly affect BIC, but coronal flutes impaired BIC. Implant types with multiple shallow microthreads had greater coronal-BIC after healing periods.
Article
Robotics
Ahmed Altameem, M. Shaheer Akhtar, Torki Altameem, H. Fouad, Sukumaran Anil, Young Soon Kim, Ahmed E. Youssef
Summary: This study introduces responsive policy decision using manifold mediator learning to improve data detection accuracy and accuracy in robot-assisted human-computer interaction applications.
INTERNATIONAL JOURNAL OF HUMANOID ROBOTICS
(2023)
Review
Dentistry, Oral Surgery & Medicine
Arunibha Ghosh, Betsy Joseph, Sukumaran Anil
Summary: This review explores the possible mechanisms underlying periodontitis in severe COVID-19 cases, including the spread of periodontal infection and microbial metabolites to the lungs, dysregulated immune system, and the connection between periodontitis and COVID-19. These mechanisms may contribute to the increased severity and mortality risk of COVID-19.
CLINICAL AND EXPERIMENTAL DENTAL RESEARCH
(2022)
Review
Dentistry, Oral Surgery & Medicine
Lakshman Samaranayake, Sukumaran Anil
Summary: Monkeypox is a contagious disease caused by the Monkeypox virus, primarily confined to African regions but recently appearing in multiple countries. This article reviews the features of Monkeypox and its potential impact on dentistry.
INTERNATIONAL DENTAL JOURNAL
(2022)
Article
Environmental Sciences
Sajith Vellappally, Sachin Naik, Omar Alsadon, Abdulaziz Abdullah Al-Kheraif, Haya Alayadi, Areej Jaber Alsiwat, Aswini Kumar, Mohamed Hashem, Nibu Varghese, Nebu George Thomas, Sukumaran Anil
Summary: This study investigated the perception of COVID-19 booster dose (CBD) vaccines among healthcare workers in India and Saudi Arabia. The results showed that there is some hesitancy among healthcare workers in both countries, with concerns about the effectiveness and possible long-term side effects of the vaccine. Males, urban residents, and post-graduates were more willing to take the booster dose.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Review
Nanoscience & Nanotechnology
Se-Kwon Kim, Sesha Subramanian Murugan, Pandurang Appana Dalavi, Sebanti Gupta, Sukumaran Anil, Gi Hun Seong, Jayachandran Venkatesan
Summary: Biomimetic materials for bone graft substitutes are an important area of research, where chitosan-based nanocomposites have been explored with silver, copper, gold, zinc oxide, titanium oxide, carbon nanotubes, graphene oxide, and biosilica. The combination of these materials stimulates the expression of bone formation genes and exhibits antibacterial activity, tissue integration, stiffness, mechanical strength, and degradation behavior, making them suitable for tissue engineering applications.
BEILSTEIN JOURNAL OF NANOTECHNOLOGY
(2022)
Review
Environmental Sciences
Ghadah Abu-Shawish, Joseph Betsy, Sukumaran Anil
Summary: This systematic review aims to explore the association between obesity and periodontitis and determine the necessity of considering obesity as a risk factor for periodontitis. Most studies showed a significant association between obesity and periodontitis, especially in females. Based on the findings, it is recommended to routinely assess the BMI of patients to offer personalized management and implement dental hygiene prevention measures for obese patients.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Review
Polymer Science
Sukumaran Anil
Summary: This review provides an overview of the characteristics and preparation methods of chitooligosaccharides, and highlights their potential and recent research progress in pharmacology and medical applications.
Article
Dentistry, Oral Surgery & Medicine
Betsy Joseph, Sukumaran Anil
Summary: This scoping review aims to map the oral manifestations of Monkeypox (MPX) disease and its management. Oral lesions include mouth sores, tongue swelling, pustular lesions on the gingiva, etc. Dental practitioners may play a crucial role in identifying the initial symptoms of MPX disease.
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Ashwathi Mathirat, Pandurang Appana Dalavi, Ashwini Prabhu, Yashaswini G. Devi, Sukumaran Anil, Kalimuthu Senthilkumar, Gi Hun Seong, Sharan S. Sargod, Sham S. Bhat, Jayachandran Venkatesan
Summary: This study successfully isolated hydroxyapatite from fish bone, which exhibits excellent biocompatibility and bioactivity, and enhances cell proliferation. The researchers evaluated the remineralization potential of the isolated nano HA and found its potential in treating early caries.
Article
Dentistry, Oral Surgery & Medicine
Betsy Joseph, Sukumaran Anil
Summary: The current outbreak of human monkeypox in 2022 has attracted significant international attention. Monkeypox virus has demonstrated human-to-human transmission potential and oral lesions have been found to manifest differently and transform from vesicles to pustules. Dental practitioners may be the first to detect the initial lesions of monkeypox and should be vigilant.
CLINICAL AND EXPERIMENTAL DENTAL RESEARCH
(2023)
Review
Dentistry, Oral Surgery & Medicine
Julie Toby Thomas, Betsy Joseph, Timo Sorsa, Matti Mauramo, Sukumaran Anil, Tuomas Waltimo
Summary: The systematic review aims to compare the levels of advanced glycation end products (AGEs) and RAGE expression in diabetic periodontitis patients with non-diabetic periodontitis patients and to identify the relationship of AGE and RAGE levels with periodontal disease severity.
Article
Engineering, Biomedical
Modhi Al Deeb, Abdullah AlFarraj Aldosari, Sukumaran Anil
Summary: This study investigated the impact of Tantalum Trabecular Metal dental implant design on implant stability and osseointegration process in rabbit femoral condyle. Twenty implants (10 Trabecular Metal and 10 Traditional Screw Vent) were placed alternately in the condyles of 10 New Zealand white rabbits. After 8 weeks, micro-CT, histological studies, and histomorphometry evaluations were used for further analysis. The TM implants showed significantly higher Bone-to-Implant Contact (BIC) and Bone Volume (BV) scores compared to TSV implants, indicating improved bone integration and ingrowth.
JOURNAL OF FUNCTIONAL BIOMATERIALS
(2023)
Article
Engineering, Biomedical
Sesha Subramanian Murugan, Pandurang Appana Dalavi, Suprith Surya, Sukumaran Anil, Sebanti Gupta, Rohan Shetty, Jayachandran Venkatesan
Summary: This study presents the development of a novel biomaterial composite scaffold that addresses the limitations of current bone grafting techniques. The scaffold, made of PLGA, MBG, MoS2, and Sim, shows promising results in terms of protein adsorption, water adsorption and retention, biodegradation, and bioactivity. In vitro and in vivo evaluations demonstrate the scaffold's biocompatibility and ability to stimulate bone regeneration.
APL BIOENGINEERING
(2023)
Review
Medicine, General & Internal
Sukumaran Anil, Priyanka Porwal, Amit Porwal
Summary: This article introduces the potential of using artificial intelligence for diagnosing dental caries, emphasizing the importance of machine learning and deep learning algorithms. The process of gathering and pre-processing data for AI examination is explained, and the applications of image processing, analysis, and classification models in diagnosing dental caries are explored. The challenges and considerations for integrating AI systems into dental practice are discussed as well.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2023)
Article
Biology
Sukumaran Anil, Ramya Ramadoss, Nebu G. Thomas, Jasmin M. George, Vishnupriya K. Sweety
Summary: Exfoliated deciduous or extracted healthy adult teeth can provide a valuable source of dental pulp stem cells for future stem cell-based regenerative medicine. Proper storage and utilization of these cells is of great importance, requiring collective responsibility from patients, dentists, and physicians.