Regulation of macrophage polarization through surface topography design to facilitate implant-to-bone osteointegration

Nano-particle mediated M2 macrophage polarization enhances bone formation and MSC osteogenesis in an IL-10 dependent manner

(2020) Olwyn R. Mahon et al.   BIOMATERIALS

Melatonin attenuates choroidal neovascularization by regulating macrophage/microglia polarization via inhibition of RhoA/ROCK signaling pathway

(2020) Yue Xu et al.   JOURNAL OF PINEAL RESEARCH

Micro-/Nanotopography on Bioresorbable Zinc Dictates Cytocompatibility, Bone Cell Differentiation, and Macrophage Polarization

(2020) Irsalan Cockerill et al.   NANO LETTERS

Activation of Both TLR and NOD Signaling Confers Host Innate Immunity-Mediated Protection Against Microbial Infection

(2019) Huiting Zhou et al.   Frontiers in Immunology

A Biomimetic Hierarchical Nanointerface Orchestrates Macrophage Polarization and Mesenchymal Stem Cell Recruitment to Promote Endogenous Bone Regeneration

(2019) Shan-Shan Jin et al.   ACS Nano

Nanoparticles from Cuttlefish Ink Inhibit Tumor Growth by Synergizing Immunotherapy and Photothermal Therapy

(2019) Rong-Hui Deng et al.   ACS Nano

Periosteal matrix-derived hydrogel promotes bone repair through an early immune regulation coupled with enhanced angio- and osteogenesis

(2019) Pengcheng Qiu et al.   BIOMATERIALS

Sarcodia suieae acetyl-xylogalactan regulate RAW 264.7 macrophage NF-kappa B activation and IL-1 beta cytokine production in macrophage polarization

(2019) Tsung-Meng Wu et al.   Scientific Reports

Bone mesenchymal stem cell secretion of sRANKL/OPG/M-CSF in response to macrophage-mediated inflammatory response influences osteogenesis on nanostructured Ti surfaces

(2018) Qian-li Ma et al.   BIOMATERIALS

Macrophages in bone fracture healing: Their essential role in endochondral ossification

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Nanostructured titanium regulates osseointegration via influencing macrophage polarization in the osteogenic environment

(2018) Jinjin Wang et al.   International Journal of Nanomedicine

The Immunomodulatory Role of BMP-2 on Macrophages to Accelerate Osteogenesis

(2018) Fei Wei et al.   TISSUE ENGINEERING PART A

The Metabolic Microenvironment Steers Bone Tissue Regeneration

(2018) Julia Loeffler et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Chloroquine modulates antitumor immune response by resetting tumor-associated macrophages toward M1 phenotype

(2018) Degao Chen et al.   Nature Communications

PPARγ induces the gene expression of integrin ανβ5 to promote macrophage M2 polarization

(2018) Qinyu Yao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Unveiling the Mechanism of Surface Hydrophilicity-Modulated Macrophage Polarization

(2018) Lin Lv et al.   Advanced Healthcare Materials

Spatial confinement downsizes the inflammatory response of macrophages

(2018) Nikhil Jain et al.   NATURE MATERIALS

Influence of patterned titanium coatings on polarization of macrophage and osteogenic differentiation of bone marrow stem cells

(2017) Zequan Zhang et al.   JOURNAL OF BIOMATERIALS APPLICATIONS

Nanoporous microstructures mediate osteogenesis by modulating the osteo-immune response of macrophages

(2017) Zetao Chen et al.   Nanoscale

Integrin-Mediated Interactions Control Macrophage Polarization in 3D Hydrogels

(2017) Byung-Hyun Cha et al.   Advanced Healthcare Materials

M2 macrophages contribute to osteogenesis and angiogenesis on nanotubular TiO2 surfaces

(2017) Jie Wang et al.   Journal of Materials Chemistry B

Valence State Manipulation of Cerium Oxide Nanoparticles on a Titanium Surface for Modulating Cell Fate and Bone Formation

(2017) Jinhua Li et al.   Advanced Science

Osteoimmunomodulation for the development of advanced bone biomaterials

(2016) Zetao Chen et al.   Materials Today

Micro- and Nanopatterned Topographical Cues for Regulating Macrophage Cell Shape and Phenotype

(2015) Thuy U. Luu et al.   ACS Applied Materials & Interfaces

Oncostatin M, an Inflammatory Cytokine Produced by Macrophages, Supports Intramembranous Bone Healing in a Mouse Model of Tibia Injury

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Biologic Scaffolds for Regenerative Medicine: Mechanisms of In vivo Remodeling

(2014) Ricardo Londono et al.   ANNALS OF BIOMEDICAL ENGINEERING

Improved implant osseointegration of a nanostructured titanium surface via mediation of macrophage polarization

(2014) Qian-Li Ma et al.   BIOMATERIALS

Physical and mechanical regulation of macrophage phenotype and function

(2014) Frances Y. McWhorter et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

MC3T3-E1 proliferation and differentiation on biphasic mixtures of Mg substituted β-tricalcium phosphate and amorphous calcium phosphate

(2014) Satish S. Singh et al.   Materials Science & Engineering C-Materials for Biological Applications

Harnessing nanotopography and integrin–matrix interactions to influence stem cell fate

(2014) Matthew J. Dalby et al.   NATURE MATERIALS

Macrophage functional polarization (M1/M2) in response to varying fiber and pore dimensions of electrospun scaffolds

(2013) Koyal Garg et al.   BIOMATERIALS

Modulation of macrophage phenotype by cell shape

(2013) F. Y. McWhorter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adsorbed Fibrinogen Enhances Production of Bone- and Angiogenic-Related Factors by Monocytes/Macrophages

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Macrophage polarization: An opportunity for improved outcomes in biomaterials and regenerative medicine

(2012) Bryan N. Brown et al.   BIOMATERIALS

Induction of Osteogenesis in Mesenchymal Stem Cells by Activated Monocytes/Macrophages Depends on Oncostatin M Signaling

(2012) Pierre Guihard et al.   STEM CELLS

Macrophage phenotype as a predictor of constructive remodeling following the implantation of biologically derived surgical mesh materials

(2011) Bryan N. Brown et al.   Acta Biomaterialia

The 'ins' and 'outs' of podosomes and invadopodia: characteristics, formation and function

(2011) Danielle A. Murphy et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Characterization of topographical effects on macrophage behavior in a foreign body response model

(2010) Sulin Chen et al.   BIOMATERIALS

Nanoscale architecture of integrin-based cell adhesions

(2010) Pakorn Kanchanawong et al.   NATURE

Human Term Placenta-Derived Mesenchymal Stromal Cells Are Less Prone to Osteogenic Differentiation Than Bone Marrow-Derived Mesenchymal Stromal Cells

(2010) Gregor A. Pilz et al.   STEM CELLS AND DEVELOPMENT

Macrophage phenotype and remodeling outcomes in response to biologic scaffolds with and without a cellular component

(2009) Bryan N. Brown et al.   BIOMATERIALS

Interstitial leukocyte migration and immune function

(2008) Peter Friedl et al.   NATURE IMMUNOLOGY

Foreign body reaction to biomaterials

(2008) James M. Anderson et al.   SEMINARS IN IMMUNOLOGY