Critical Role of Perforin-dependent CD8+ T Cell Immunity for Rapid Protective Vaccination in a Murine Model for Human Smallpox

Gamma Interferon and Perforin Control the Strength, but Not the Hierarchy, of Immunodominance of an Antiviral CD8+ T Cell Response

(2011) S. Remakus et al.   JOURNAL OF VIROLOGY

N1L Is an Ectromelia Virus Virulence Factor and Essential for In Vivo Spread upon Respiratory Infection

(2011) M. S. Gratz et al.   JOURNAL OF VIROLOGY

Safety and immunogenicity of two freeze-dried Vero cell rabies vaccines for human use in post-exposure prophylaxis

(2011) Ling-yun Wang et al.   VACCINE

Adoptive transfer of pp65-specific T cells for the treatment of chemorefractory cytomegalovirus disease or reactivation after haploidentical and matched unrelated stem cell transplantation

(2010) T. Feuchtinger et al.   BLOOD

Concomitant type I IFN receptor-triggering of T cells and of DC is required to promote maximal modified vaccinia virus Ankara-induced T-cell expansion

(2010) Theresa Frenz et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Antiviral protection following immunization correlates with humoral but not cell-mediated immunity

(2010) Vijay Panchanathan et al.   IMMUNOLOGY AND CELL BIOLOGY

Age-dependent susceptibility to a viral disease due to decreased natural killer cell numbers and trafficking

(2010) Min Fang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Evaluation of Cytomegalovirus (CMV)–Specific T Cell Immune Reconstitution Revealed That Baseline Antiviral Immunity, Prophylaxis, or Preemptive Therapy but not Antithymocyte Globulin Treatment Contribute to CMV‐Specific T Cell Reconstitution in Kidney Transplant Recipients

(2010) Davide Abate et al.   JOURNAL OF INFECTIOUS DISEASES

First-in-human clinical trials with vaccines—what regulators want

(2010) Karen B Goetz et al.   NATURE BIOTECHNOLOGY

Immune Requirements of Post-Exposure Immunization with Modified Vaccinia Ankara of Lethally Infected Mice

(2010) Henning Lauterbach et al.   PLoS One

Major increase in human monkeypox incidence 30 years after smallpox vaccination campaigns cease in the Democratic Republic of Congo

(2010) A. W. Rimoin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Memories that last forever: strategies for optimizing vaccine T-cell memory

(2009) J. D. Ahlers et al.   BLOOD

Generating memory with vaccination

(2009) Flora Castellino et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Candidate influenza vaccines based on recombinant modified vaccinia virus Ankara

(2009) Guus F Rimmelzwaan et al.   Expert Review of Vaccines

Prospects for an influenza vaccine that induces cross-protective cytotoxic T lymphocytes

(2009) Lorena E Brown et al.   IMMUNOLOGY AND CELL BIOLOGY

Induced bronchus-associated lymphoid tissue serves as a general priming site for T cells and is maintained by dendritic cells

(2009) Stephan Halle et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Evaluation of smallpox vaccines using variola neutralization

(2009) I. K. Damon et al.   JOURNAL OF GENERAL VIROLOGY

Modified Vaccinia Virus Ankara Triggers Chemotaxis of Monocytes and Early Respiratory Immigration of Leukocytes by Induction of CCL2 Expression

(2009) M. H. Lehmann et al.   JOURNAL OF VIROLOGY

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

(2009) Veit Hornung et al.   NATURE

T cell receptor sharing by cytotoxic T lymphocytes facilitates efficient virus control

(2009) G. Chaudhri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effective post-exposure protection against lethal orthopoxviruses infection by vaccinia immune globulin involves induction of adaptive immune response

(2009) Shlomo Lustig et al.   VACCINE

Evidence for a 4-dose vaccine schedule for human rabies post-exposure prophylaxis in previously non-vaccinated individuals

(2009) Charles E. Rupprecht et al.   VACCINE

A randomized, double-blind, dose-finding Phase II study to evaluate immunogenicity and safety of the third generation smallpox vaccine candidate IMVAMUNE®

(2009) Alfred von Krempelhuber et al.   VACCINE

Innate Immune Sensing of Modified Vaccinia Virus Ankara (MVA) Is Mediated by TLR2-TLR6, MDA-5 and the NALP3 Inflammasome

(2009) Julie Delaloye et al.   PLoS Pathogens

The Poxvirus Vectors MVA and NYVAC as Gene Delivery Systems for Vaccination Against Infectious Diseases and Cancer

(2008) Carmen Gomez et al.   CURRENT GENE THERAPY

Survival of lethal poxvirus infection in mice depends on TLR9, and therapeutic vaccination provides protection

(2008) Christofer Samuelsson et al.   JOURNAL OF CLINICAL INVESTIGATION

Postexposure Immunization with Modified Vaccinia Virus Ankara or Conventional Lister Vaccine Provides Solid Protection in a Murine Model of Human Smallpox

(2008) Nir Paran et al.   JOURNAL OF INFECTIOUS DISEASES

Vaccinia Virus-Mediated Inhibition of Type I Interferon Responses Is a Multifactorial Process Involving the Soluble Type I Interferon Receptor B18 and Intracellular Components

(2008) Z. Waibler et al.   JOURNAL OF VIROLOGY

A Role for NKG2D in NK Cell–Mediated Resistance to Poxvirus Disease

(2008) Min Fang et al.   PLoS Pathogens

Rapid protection in a monkeypox model by a single injection of a replication-deficient vaccinia virus

(2008) P. L. Earl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Surviving Mousepox Infection Requires the Complement System

(2008) Elizabeth A. Moulton et al.   PLoS Pathogens