Genetic, molecular and physiological mechanisms involved in human obesity: Society for Endocrinology Medal Lecture 2012

KSR2 Mutations Are Associated with Obesity, Insulin Resistance, and Impaired Cellular Fuel Oxidation

(2013) Laura R. Pearce et al.   CELL

Rare variants in single-minded 1 (SIM1) are associated with severe obesity

(2013) Shwetha Ramachandrappa et al.   JOURNAL OF CLINICAL INVESTIGATION

Loss of Function of the Melanocortin 2 Receptor Accessory Protein 2 Is Associated with Mammalian Obesity

(2013) M. Asai et al.   SCIENCE

AMP-Activated Protein Kinase: A Target for Drugs both Ancient and Modern

(2012) D. Grahame Hardie et al.   CHEMISTRY & BIOLOGY

Melanocortin-4 Receptor Signaling Is Required for Weight Loss after Gastric Bypass Surgery

(2012) Ida J. Hatoum et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Human SH2B1 mutations are associated with maladaptive behaviors and obesity

(2012) Michael E. Doche et al.   JOURNAL OF CLINICAL INVESTIGATION

Leptin Deficiency and Diet-Induced Obesity Reduce Hypothalamic Kisspeptin Expression in Mice

(2011) Janette H. Quennell et al.   ENDOCRINOLOGY

Leptin Replacement Prevents Weight Loss-Induced Metabolic Adaptation in Congenital Leptin-Deficient Patients

(2010) Jose E. Galgani et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Pharmacological Chaperones Restore Function to MC4R Mutants Responsible for Severe Early-Onset Obesity

(2010) P. Rene et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Obesity Genotype Score and Cardiovascular Risk in Women With Type 2 Diabetes Mellitus

(2009) Meian He et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

SH2B1 Enhances Insulin Sensitivity by Both Stimulating the Insulin Receptor and Inhibiting Tyrosine Dephosphorylation of Insulin Receptor Substrate Proteins

(2009) D. L. Morris et al.   DIABETES

Regulation of Jak2 Function by Phosphorylation of Tyr317 and Tyr637 during Cytokine Signaling

(2009) S. A. Robertson et al.   MOLECULAR AND CELLULAR BIOLOGY

Large, rare chromosomal deletions associated with severe early-onset obesity

(2009) Elena G. Bochukova et al.   NATURE

Brain-Derived Neurotrophic Factor and Obesity in the WAGR Syndrome

(2008) Joan C. Han et al.   NEW ENGLAND JOURNAL OF MEDICINE

Modulation of Blood Pressure by Central Melanocortinergic Pathways

(2008) Jerry R. Greenfield et al.   NEW ENGLAND JOURNAL OF MEDICINE