Rare variants in single-minded 1 (SIM1) are associated with severe obesity

Loss-of-function mutations in SIM1 contribute to obesity and Prader-Willi–like features

(2013) Amélie Bonnefond et al.   JOURNAL OF CLINICAL INVESTIGATION

Ablation of Sim1 Neurons Causes Obesity through Hyperphagia and Reduced Energy Expenditure

(2012) Dong Xi et al.   PLoS One

Crystal Structure of the Heterodimeric CLOCK:BMAL1 Transcriptional Activator Complex

(2012) N. Huang et al.   SCIENCE

Structure of an Enclosed Dimer Formed by the Drosophila Period Protein

(2011) Heather A. King et al.   JOURNAL OF MOLECULAR BIOLOGY

Coactivators necessary for transcriptional output of the hypoxia inducible factor, HIF, are directly recruited by ARNT PAS-B

(2011) C. L. Partch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Obesity due to Melanocortin 4 Receptor (MC4R) Deficiency Is Associated with Increased Linear Growth and Final Height, Fasting Hyperinsulinemia, and Incompletely Suppressed Growth Hormone Secretion

(2010) Carlos E. Martinelli et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Postnatal Sim1 Deficiency Causes Hyperphagic Obesity and Reduced Mc4r and Oxytocin Expression

(2010) K. P. Tolson et al.   JOURNAL OF NEUROSCIENCE

Analysis of the SIM1 Contribution to Polygenic Obesity in the French Population

(2010) Maya Ghoussaini et al.   Obesity

Development of a new physics-based internal coordinate mechanics force field and its application to protein loop modeling

(2010) Yelena A. Arnautova et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Common Variation in SIM1 Is Reproducibly Associated With BMI in Pi ma Indians

(2009) M. Traurig et al.   DIABETES

Impact of Sim1 gene dosage on the development of the paraventricular and supraoptic nuclei of the hypothalamus

(2009) Sabine Michaëlle Duplan et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The HIF1α-inducible pro-cell death gene BNIP3 is a novel target of SIM2s repression through cross-talk on the hypoxia response element

(2009) A L Farrall et al.   ONCOGENE

Artificial ligand binding within the HIF2  PAS-B domain of the HIF2 transcription factor

(2009) T. H. Scheuermann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oxytocin Deficiency Mediates Hyperphagic Obesity ofSim1Haploinsufficient Mice

(2008) Bassil M. Kublaoui et al.   MOLECULAR ENDOCRINOLOGY

Modulation of Blood Pressure by Central Melanocortinergic Pathways

(2008) Jerry R. Greenfield et al.   NEW ENGLAND JOURNAL OF MEDICINE

The bHLH/Per-Arnt-Sim transcription factor SIM2 regulates muscle transcript myomesin2 via a novel, non-canonical E-box sequence

(2008) Susan Woods et al.   NUCLEIC ACIDS RESEARCH