Regulation of mitochondrial ceramide distribution by members of the BCL-2 family

BAK activation is necessary and sufficient to drive ceramide synthase-dependent ceramide accumulation following inhibition of BCL2-like proteins

(2013) Levi J. Beverly et al.   BIOCHEMICAL JOURNAL

Emerging roles of lipids in BCL-2 family-regulated apoptosis

(2013) Tejia Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Myristate-derived d16:0 Sphingolipids Constitute a Cardiac Sphingolipid Pool with Distinct Synthetic Routes and Functional Properties

(2013) Sarah Brice Russo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sphingolipid Metabolism Cooperates with BAK and BAX to Promote the Mitochondrial Pathway of Apoptosis

(2012) Jerry E. Chipuk et al.   CELL

The control of the balance between ceramide and sphingosine-1-phosphate by sphingosine kinase: Oxidative stress and the seesaw of cell survival and death

(2012) James R. Van Brocklyn et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY

Long chain ceramides and very long chain ceramides have opposite effects on human breast and colon cancer cell growth

(2012) Daniela Hartmann et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Efficient Synthesis of a Styryl Analogue of (2S,3R,4E)-N2-Octadecanoyl-4-tetradecasphingenine via Cross-Metathesis Reaction

(2011) Gulshan Kumar et al.   HELVETICA CHIMICA ACTA

Mitochondrial Ceramide-Rich Macrodomains Functionalize Bax upon Irradiation

(2011) Hyunmi Lee et al.   PLoS One

Ceramide and activated Bax act synergistically to permeabilize the mitochondrial outer membrane

(2010) Vidyaramanan Ganesan et al.   APOPTOSIS

Apoptosis-induced changes in mitochondrial lipids

(2010) Massimo Crimi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The BCL-2 Protein BAK Is Required for Long-chain Ceramide Generation during Apoptosis

(2010) Leah J. Siskind et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Bcl-2 family in autoimmune and degenerative disorders

(2009) Delphine Mérino et al.   APOPTOSIS

Cytochrome c/cardiolipin relations in mitochondria: a kiss of death

(2009) Valerian E. Kagan et al.   FREE RADICAL BIOLOGY AND MEDICINE

The SPTLC3 Subunit of Serine Palmitoyltransferase Generates Short Chain Sphingoid Bases

(2009) Thorsten Hornemann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BAX activation is initiated at a novel interaction site

(2008) Evripidis Gavathiotis et al.   NATURE

Dual role of proapoptotic BAD in insulin secretion and beta cell survival

(2008) Nika N Danial et al.   NATURE MEDICINE

Bcl-2 family proteins and cancer

(2008) K W Yip et al.   ONCOGENE