A distinct immunogenic region of glutamic acid decarboxylase 65 is naturally processed and presented by human islet cells to cytotoxic CD8 T cells

Multi-parametric flow cytometric and genetic investigation of the peripheral B cell compartment in human type 1 diabetes

(2014) W. S. Thompson et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

IGRP and insulin vaccination induce CD8+ T cell-mediated autoimmune diabetes in the RIP-CD80GP mouse

(2014) Y. F. Fuchs et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Comparison of peptide-major histocompatibility complex tetramers and dextramers for the identification of antigen-specific T cells

(2014) G. Dolton et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Progress in immune-based therapies for type 1 diabetes

(2013) M. von Herrath et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

HLA-A*01:03, HLA-A*24:02, HLA-B*08:01, HLA-B*27:05, HLA-B*35:01, HLA-B*44:02, and HLA-C*07:01 Monochain Transgenic/H-2 Class I Null Mice: Novel Versatile Preclinical Models of Human T Cell Responses

(2013) R. Boucherma et al.   JOURNAL OF IMMUNOLOGY

Plasmid-Encoded Proinsulin Preserves C-Peptide While Specifically Reducing Proinsulin-Specific CD8+ T Cells in Type 1 Diabetes

(2013) B. O. Roep et al.   Science Translational Medicine

Peptide length determines the outcome of TCR/peptide-MHCI engagement

(2012) J. Ekeruche-Makinde et al.   BLOOD

Human β-Cell Killing by Autoreactive Preproinsulin-Specific CD8 T Cells Is Predominantly Granule-Mediated With the Potency Dependent Upon T-Cell Receptor Avidity

(2012) Robin R. Knight et al.   DIABETES

Circulating Preproinsulin Signal Peptide-Specific CD8 T Cells Restricted by the Susceptibility Molecule HLA-A24 Are Expanded at Onset of Type 1 Diabetes and Kill  -Cells

(2012) D. Kronenberg et al.   DIABETES

Zinc transporter (ZnT)8186–194 is an immunodominant CD8+ T cell epitope in HLA-A2+ type 1 diabetic patients

(2012) M. Scotto et al.   DIABETOLOGIA

Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients

(2012) Ken T. Coppieters et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Identification of novel HLA-A*0201-restricted cytotoxic T lymphocyte epitopes from Zinc Transporter 8

(2012) Shufa Li et al.   VACCINE

Diabetogenic T lymphocytes in human Type 1 diabetes

(2011) Bart O Roep et al.   CURRENT OPINION IN IMMUNOLOGY

Immunology of Diabetes Society T-Cell Workshop: HLA class I tetramer-directed epitope validation initiative T-Cell Workshop Report-HLA Class I Tetramer Validation Initiative

(2011) R. Mallone et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Simultaneous Detection of Circulating Autoreactive CD8+ T-Cells Specific for Different Islet Cell-Associated Epitopes Using Combinatorial MHC Multimers

(2010) J. H. Velthuis et al.   DIABETES

HLArestrictor—a tool for patient-specific predictions of HLA restriction elements and optimal epitopes within peptides

(2010) Malene Erup Larsen et al.   IMMUNOGENETICS

Allele frequency net: a database and online repository for immune gene frequencies in worldwide populations

(2010) F. F. Gonzalez-Galarza et al.   NUCLEIC ACIDS RESEARCH

Tricks with tetramers: how to get the most from multimeric peptide-MHC

(2009) Linda Wooldridge et al.   IMMUNOLOGY

Detection of GAD65 Autoreactive T-Cells by HLA Class I Tetramers in Type 1 Diabetic Patients

(2009) Laura Giuliani et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

The Immune Epitope Database 2.0

(2009) Randi Vita et al.   NUCLEIC ACIDS RESEARCH

Analysis of islet inflammation in human type 1 diabetes

(2008) A. Willcox et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY