Genetic variants in the region of the C1q genes are associated with rheumatoid arthritis

Complement C1q Activates Canonical Wnt Signaling and Promotes Aging-Related Phenotypes

(2012) Atsuhiko T. Naito et al.   CELL

Complement in the immunopathogenesis of rheumatic disease

(2012) Gunnar Sturfelt et al.   Nature Reviews Rheumatology

The influence of ACPA status and characteristics on the course of RA

(2012) Annemiek Willemze et al.   Nature Reviews Rheumatology

TRAF1/C5, eNOS, C1q, but not STAT4 and PTPN22 gene polymorphisms are associated with genetic susceptibility to systemic lupus erythematosus in Turkey

(2011) Maria I. Zervou et al.   HUMAN IMMUNOLOGY

Complement activation by (auto-) antibodies

(2011) Nina A. Daha et al.   MOLECULAR IMMUNOLOGY

Anti-citrullinated protein antibodies have a low avidity compared with antibodies against recall antigens

(2010) P. Suwannalai et al.   ANNALS OF THE RHEUMATIC DISEASES

Mice lacking C1q or C3 show accelerated rejection of minor H disparate skin grafts and resistance to induction of tolerance

(2010) Paramita Baruah et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The non-classical functions of the classical complement pathway recognition subcomponent C1q

(2010) Annapurna Nayak et al.   IMMUNOLOGY LETTERS

Infiltrating dendritic cells contribute to local synthesis of C1q in murine and human lupus nephritis

(2010) Giuseppe Castellano et al.   MOLECULAR IMMUNOLOGY

Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

(2010) Eli A Stahl et al.   NATURE GENETICS

Complement: a key system for immune surveillance and homeostasis

(2010) Daniel Ricklin et al.   NATURE IMMUNOLOGY

C1q inhibits immune complex-induced interferon-α production in plasmacytoid dendritic cells: A novel link between C1q deficiency and systemic lupus erythematosus pathogenesis

(2009) Christian Lood et al.   ARTHRITIS AND RHEUMATISM

Anti-cyclic citrullinated peptide antibodies from rheumatoid arthritis patients activate complement via both the classical and alternative pathways

(2009) L. A. Trouw et al.   ARTHRITIS AND RHEUMATISM

C1q enhances IFN-  production by antigen-specific T cells via the CD40 costimulatory pathway on dendritic cells

(2009) P. Baruah et al.   BLOOD

Evaluation of C1q genomic region in minority racial groups of lupus

(2009) B Namjou et al.   GENES AND IMMUNITY

Complement activation and inhibition: a delicate balance

(2009) A.P. Sjöberg et al.   TRENDS IN IMMUNOLOGY

Analysis of C1q polymorphisms suggests association with systemic lupus erythematosus, serum C1q and CH50 levels and disease severity

(2008) H A Martens et al.   ANNALS OF THE RHEUMATIC DISEASES

A Polymorphism in the Complement Component C1qA Correlates with Prolonged Response Following Rituximab Therapy of Follicular Lymphoma

(2008) E. Racila et al.   CLINICAL CANCER RESEARCH

Association of a TRAF1 and a STAT4 gene polymorphism with increased risk for rheumatoid arthritis in a genetically homogeneous population

(2008) Maria I. Zervou et al.   HUMAN IMMUNOLOGY

Complement production and regulation by dendritic cells: Molecular switches between tolerance and immunity

(2008) Cees van Kooten et al.   MOLECULAR IMMUNOLOGY

Common variants at CD40 and other loci confer risk of rheumatoid arthritis

(2008) Soumya Raychaudhuri et al.   NATURE GENETICS

C1q deficiency promotes the production of transgenic-derived IgM and IgG3 autoantibodies in anti-DNA knock-in transgenic mice

(2007) Liliane Fossati-Jimack et al.   MOLECULAR IMMUNOLOGY

Role of complement and complement regulators in the removal of apoptotic cells

(2007) L.A. Trouw et al.   MOLECULAR IMMUNOLOGY