Wnt signaling induces gene expression of factors associated with bone destruction in lung and breast cancer

Deletion of beta catenin in hypertrophic growth plate chondrocytes impairs trabecular bone formation

(2013) Svitlana Golovchenko et al.   BONE

Tumor-Stroma Interaction: Revealing Fibroblast-Secreted Exosomes as Potent Regulators of Wnt-Planar Cell Polarity Signaling in Cancer Metastasis

(2013) V. Luga et al.   CANCER RESEARCH

Phase I Study of the Hedgehog Pathway Inhibitor IPI-926 in Adult Patients with Solid Tumors

(2013) A. Jimeno et al.   CLINICAL CANCER RESEARCH

The Primary Function of gp130 Signaling in Osteoblasts Is To Maintain Bone Formation and Strength, Rather Than Promote Osteoclast Formation

(2013) Rachelle W Johnson et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Expanded access study of patients with advanced basal cell carcinoma treated with the Hedgehog pathway inhibitor, vismodegib

(2013) Anne Lynn S. Chang et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Bone Morphogenetic Proteins Stimulate Mammary Fibroblasts to Promote Mammary Carcinoma Cell Invasion

(2013) Philip Owens et al.   PLoS One

Paracrine Wnt signaling both promotes and inhibits human breast tumor growth

(2013) J. L. Green et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Thrombospondin-4 expression is activated during the stromal response to invasive breast cancer

(2013) Amy E. McCart Reed et al.   VIRCHOWS ARCHIV

Mesenchymal Stem Cells Provide an Advantageous Tumor Microenvironment for the Restoration of Cancer Stem Cells

(2012) Kanako Nishimura et al.   PATHOBIOLOGY

Expression of Dickkopf-1 and Beta-Catenin Related to the Prognosis of Breast Cancer Patients with Triple Negative Phenotype

(2012) Wen-Huan Xu et al.   PLoS One

Myeloid-derived suppressor cells expand during breast cancer progression and promote tumor-induced bone destruction

(2012) Sabrina Danilin et al.   OncoImmunology

Subtype-specific alterations of the Wnt signaling pathway in breast cancer: Clinical and prognostic significance

(2011) Nupur Mukherjee et al.   CANCER SCIENCE

Tyrosine phosphorylation of transcriptional coactivator WW-domain binding protein 2 regulates estrogen receptor α function in breast cancer via the Wnt pathway

(2011) Shen Kiat Lim et al.   FASEB JOURNAL

Mechanical signaling through the cytoskeleton regulates cell proliferation by coordinated focal adhesion and Rho GTPase signaling

(2011) P. P. Provenzano et al.   JOURNAL OF CELL SCIENCE

Interactions between cancer stem cells and their niche govern metastatic colonization

(2011) Ilaria Malanchi et al.   NATURE

Anti-Transforming Growth Factor ß Antibody Treatment Rescues Bone Loss and Prevents Breast Cancer Metastasis to Bone

(2011) Swati Biswas et al.   PLoS One

Regulation of β-Catenin Nuclear Dynamics by GSK-3β Involves a LEF-1 Positive Feedback Loop

(2011) Cara Jamieson et al.   TRAFFIC

Bone Structural Components Regulating Sites of Tumor Metastasis

(2011) Julie A. Sterling et al.   Current Osteoporosis Reports

Longitudinal live animal micro-CT allows for quantitative analysis of tumor-induced bone destruction

(2010) Lindsay C. Johnson et al.   BONE

Advances in the biology of bone metastasis: How the skeleton affects tumor behavior

(2010) Julie A. Sterling et al.   BONE

TGF-  Promotion of Gli2-Induced Expression of Parathyroid Hormone-Related Protein, an Important Osteolytic Factor in Bone Metastasis, Is Independent of Canonical Hedgehog Signaling

(2010) R. W. Johnson et al.   CANCER RESEARCH

β-catenin-independent WNT signaling in basal-like breast cancer and brain metastasis

(2010) F. Klemm et al.   CARCINOGENESIS

Transcriptional crosstalk between TGFβ and stem cell pathways in tumor cell invasion: Role of EMT promoting Smad complexes

(2010) Jonas Fuxe et al.   CELL CYCLE

Interaction between human-breast cancer metastasis and bone microenvironment through activated hepatocyte growth factor/Met and β-catenin/Wnt pathways

(2010) Sara Previdi et al.   EUROPEAN JOURNAL OF CANCER

Matrix stiffness modulates proliferation, chemotherapeutic response, and dormancy in hepatocellular carcinoma cells

(2010) Jörg Schrader et al.   HEPATOLOGY

Targeted therapy for high-grade glioma with the TGF- 2 inhibitor trabedersen: results of a randomized and controlled phase IIb study

(2010) U. Bogdahn et al.   NEURO-ONCOLOGY

Matrix Rigidity Induces Osteolytic Gene Expression of Metastatic Breast Cancer Cells

(2010) Nazanin S. Ruppender et al.   PLoS One

Forcing form and function: biomechanical regulation of tumor evolution

(2010) Hongmei Yu et al.   TRENDS IN CELL BIOLOGY

Boundary Stiffness Regulates Fibroblast Behavior in Collagen Gels

(2009) Jeffrey John et al.   ANNALS OF BIOMEDICAL ENGINEERING

Comparing the mechanical influence of vinculin, focal adhesion kinase and p53 in mouse embryonic fibroblasts

(2009) Anna H. Klemm et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cloning of the HumanGLI2Promoter

(2009) Sylviane Dennler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stromal Transforming Growth Factor-  Signaling Mediates Prostatic Response to Androgen Ablation by Paracrine Wnt Activity

(2008) V. R. Placencio et al.   CANCER RESEARCH