Arginase inhibition improves endothelial function in patients with familial hypercholesterolaemia irrespective of their cholesterol levels

OxLDL Triggers Retrograde Translocation of Arginase2 in Aortic Endothelial Cells via ROCK and Mitochondrial Processing Peptidase

(2014) Deepesh Pandey et al.   CIRCULATION RESEARCH

Effect of Arginase Inhibition on Ischemia-Reperfusion Injury in Patients with Coronary Artery Disease with and without Diabetes Mellitus

(2014) Oskar Kövamees et al.   PLoS One

Endothelial nitric oxide synthase activation through obacunone-dependent arginase inhibition restored impaired endothelial function in ApoE-null mice

(2014) Jeongyeon Yoon et al.   VASCULAR PHARMACOLOGY

Maternal Hypercholesterolemia in Pregnancy Associates With Umbilical Vein Endothelial Dysfunction

(2013) Andrea Leiva et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Arginase as a potential target in the treatment of cardiovascular disease: reversal of arginine steal?

(2013) John Pernow et al.   CARDIOVASCULAR RESEARCH

Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: Consensus Statement of the European Atherosclerosis Society

(2013) B. G. Nordestgaard et al.   EUROPEAN HEART JOURNAL

Arginase Inhibition Improves Endothelial Function in Patients With Coronary Artery Disease and Type 2 Diabetes Mellitus

(2012) Alexey Shemyakin et al.   CIRCULATION

Nitric Oxide-Mediated Endothlium-Dependent Vasodilation Is Impaired with Borderline High-LDL Cholesterol

(2012) Kyle J. Diehl et al.   CTS-Clinical and Translational Science

Nitric oxide synthases: regulation and function

(2011) U. Forstermann et al.   EUROPEAN HEART JOURNAL

Oral atorvastatin therapy restores cutaneous microvascular function by decreasing arginase activity in hypercholesterolaemic humans

(2011) Lacy A. Holowatz et al.   JOURNAL OF PHYSIOLOGY-LONDON

Inhibition of human arginase I by substrate and product analogues

(2010) Luigi Di Costanzo et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

OxLDL-dependent activation of arginase II is dependent on the LOX-1 receptor and downstream RhoA signaling

(2010) Sungwoo Ryoo et al.   ATHEROSCLEROSIS

No evidence of impaired endothelial function or altered inflammatory state in patients with familial hypercholesterolemia treated with statins

(2010) Anders Hovland et al.   Journal of Clinical Lipidology

Endothelial Arginase II

(2008) Sungwoo Ryoo et al.   CIRCULATION RESEARCH

Diabetes-induced Coronary Vascular Dysfunction Involves Increased Arginase Activity

(2007) Maritza J. Romero et al.   CIRCULATION RESEARCH