The Scaffold Protein Muscle A-Kinase Anchoring Protein β Orchestrates Cardiac Myocyte Hypertrophic Signaling Required for the Development of Heart Failure

Calcineurin activity is required for cardiac remodelling in pregnancy

(2013) Eunhee Chung et al.   CARDIOVASCULAR RESEARCH

Phospholipase Cε Hydrolyzes Perinuclear Phosphatidylinositol 4-Phosphate to Regulate Cardiac Hypertrophy

(2013) Lianghui Zhang et al.   CELL

Pathological Ventricular Remodeling

(2013) Jana S. Burchfield et al.   CIRCULATION

AKAP13 Rho-GEF and PKD-Binding Domain Deficient Mice Develop Normally but Have an Abnormal Response to β-Adrenergic-Induced Cardiac Hypertrophy

(2013) Matthew J. Spindler et al.   PLoS One

Myocyte enhancer factor 2 (MEF2) tethering to muscle selective A-kinase anchoring protein (mAKAP) is necessary for myogenic differentiation

(2012) Maximilian A.X. Vargas et al.   CELLULAR SIGNALLING

Anchored p90 Ribosomal S6 Kinase 3 Is Required for Cardiac Myocyte Hypertrophy

(2012) Jinliang Li et al.   CIRCULATION RESEARCH

Increased Oxidative Stress in the Nucleus Caused by Nox4 Mediates Oxidation of HDAC4 and Cardiac Hypertrophy

(2012) Shouji Matsushima et al.   CIRCULATION RESEARCH

Regulation of MEF2 transcriptional activity by calcineurin/mAKAP complexes

(2012) Jinliang Li et al.   EXPERIMENTAL CELL RESEARCH

Phospholipase Cϵ Scaffolds to Muscle-specific A Kinase Anchoring Protein (mAKAPβ) and Integrates Multiple Hypertrophic Stimuli in Cardiac Myocytes

(2011) Lianghui Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AKAPs: The architectural underpinnings of local cAMP signaling

(2011) Michael D. Kritzer et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Assessment of left ventricular function in aortic stenosis

(2011) Alper Ozkan et al.   Nature Reviews Cardiology

Scaffold Proteins: Hubs for Controlling the Flow of Cellular Information

(2011) M. C. Good et al.   SCIENCE

Targeted Deletion of the Extracellular Signal-Regulated Protein Kinase 5 Attenuates Hypertrophic Response and Promotes Pressure Overload–Induced Apoptosis in the Heart

(2010) Tomomi E. Kimura et al.   CIRCULATION RESEARCH

Extracellular Signal-Regulated Kinases 1 and 2 Regulate the Balance Between Eccentric and Concentric Cardiac Growth

(2010) Izhak Kehat et al.   CIRCULATION RESEARCH

Robust cardiomyocyte-specific gene expression following systemic injection of AAV: in vivo gene delivery follows a Poisson distribution

(2010) K-M R Prasad et al.   GENE THERAPY

A novel kinase inhibitor establishes a predominant role for protein kinase D as a cardiac class IIa histone deacetylase kinase

(2009) Lauren Monovich et al.   FEBS LETTERS

An Adenylyl Cyclase-mAKAPβ Signaling Complex Regulates cAMP Levels in Cardiac Myocytes

(2009) Michael S. Kapiloff et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The mAKAPβ scaffold regulates cardiac myocyte hypertrophy via recruitment of activated calcineurin

(2009) Jinliang Li et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Glycogen synthase kinase 3 (GSK3) in the heart: a point of integration in hypertrophic signalling and a therapeutic target? A critical analysis

(2008) P H Sugden et al.   BRITISH JOURNAL OF PHARMACOLOGY

NFATc2 Is a Necessary Mediator of Calcineurin-dependent Cardiac Hypertrophy and Heart Failure

(2008) Meriem Bourajjaj et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The MEF2D transcription factor mediates stress-dependent cardiac remodeling in mice

(2008) Yuri Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

A new type of ERK1/2 autophosphorylation causes cardiac hypertrophy

(2008) Kristina Lorenz et al.   NATURE MEDICINE

The RSK family of kinases: emerging roles in cellular signalling

(2008) Rana Anjum et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Requirement of protein kinase D1 for pathological cardiac remodeling

(2008) J. Fielitz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

mAKAP Compartmentalizes Oxygen-Dependent Control of HIF-1 

(2008) W. Wong et al.   Science Signaling