Anchoring Proteins as Regulators of Signaling Pathways

Ryanodine Receptor S2808 Phosphorylation in Heart Failure

(2012) Donald M. Bers   CIRCULATION RESEARCH

Hyperphosphorylation of the Cardiac Ryanodine Receptor at Serine 2808 Is Not Involved in Cardiac Dysfunction After Myocardial Infarction

(2012) Hongyu Zhang et al.   CIRCULATION RESEARCH

The influence of lipids on voltage-gated ion channels

(2012) Qiu-Xing Jiang et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

A-kinase anchoring proteins: scaffolding proteins in the heart

(2011) Dario Diviani et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Myomegalin is a novel A-kinase anchoring protein involved in the phosphorylation of cardiac myosin binding protein C

(2011) Gerrida M Uys et al.   BMC CELL BIOLOGY

Phosphodiesterase 4D Regulates Baseline Sarcoplasmic Reticulum Ca 2+ Release and Cardiac Contractility, Independently of L-Type Ca 2+ Current

(2011) Sanja Beca et al.   CIRCULATION RESEARCH

Restoration of Normal L-Type Ca 2+ Channel Function During Timothy Syndrome by Ablation of an Anchoring Protein

(2011) Edward P. Cheng et al.   CIRCULATION RESEARCH

Deletion of the Distal C Terminus of CaV1.2 Channels Leads to Loss of β-Adrenergic Regulation and Heart Failurein Vivo

(2011) Ying Fu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Palmitoylation Targets AKAP79 Protein to Lipid Rafts and Promotes Its Regulation of Calcium-sensitive Adenylyl Cyclase Type 8

(2011) Ilse Delint-Ramirez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phospholipase Cϵ Scaffolds to Muscle-specific A Kinase Anchoring Protein (mAKAPβ) and Integrates Multiple Hypertrophic Stimuli in Cardiac Myocytes

(2011) Lianghui Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Decreased cardiac L-type Ca2+ channel activity induces hypertrophy and heart failure in mice

(2011) Sanjeewa A. Goonasekera et al.   JOURNAL OF CLINICAL INVESTIGATION

Reorganized PKA-AKAP associations in the failing human heart

(2011) Thin-Thin Aye et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Confinement of β1- and β2-adrenergic receptors in the plasma membrane of cardiomyocyte-like H9c2 cells is mediated by selective interactions with PDZ domain and A-kinase anchoring proteins but not caveolae

(2011) Cathleen D. Valentine et al.   MOLECULAR BIOLOGY OF THE CELL

Fine-Tuning of Drp1/Fis1 Availability by AKAP121/Siah2 Regulates Mitochondrial Adaptation to Hypoxia

(2011) Hyungsoo Kim et al.   MOLECULAR CELL

Integrating Cardiac PIP3 and cAMP Signaling through a PKA Anchoring Function of p110γ

(2011) Alessia Perino et al.   MOLECULAR CELL

An entirely specific type I A-kinase anchoring protein that can sequester two molecules of protein kinase A at mitochondria

(2011) C. K. Means et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Architecture and dynamics of an A-kinase anchoring protein 79 (AKAP79) signaling complex

(2011) M. G. Gold et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AKAP121 downregulation impairs protective cAMP signals, promotes mitochondrial dysfunction, and increases oxidative stress

(2010) Cinzia Perrino et al.   CARDIOVASCULAR RESEARCH

Cardiac mitochondria and arrhythmias

(2010) D. A. Brown et al.   CARDIOVASCULAR RESEARCH

Sphingosine Kinase Interacting Protein is an A-Kinase Anchoring Protein Specific for Type I cAMP-Dependent Protein Kinase

(2010) Duangnapa Kovanich  et al.   CHEMBIOCHEM

Inhibiting Mitochondrial Fission Protects the Heart Against Ischemia/Reperfusion Injury

(2010) Sang-Bing Ong et al.   CIRCULATION

Increased Coupled Gating of L-Type Ca 2+ Channels During Hypertension and Timothy Syndrome

(2010) Manuel F. Navedo et al.   CIRCULATION RESEARCH

Sympathetic Stimulation of Adult Cardiomyocytes Requires Association of AKAP5 With a Subpopulation of L-Type Calcium Channels

(2010) C. Blake Nichols et al.   CIRCULATION RESEARCH

Small Molecule AKAP-Protein Kinase A (PKA) Interaction Disruptors That Activate PKA Interfere with Compartmentalized cAMP Signaling in Cardiac Myocytes

(2010) Frank Christian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Rho Guanine Nucleotide Exchange Factor AKAP13 (BRX) Is Essential for Cardiac Development in Mice

(2010) Chantal M. Mayers et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cardiac Troponin T, a Sarcomeric AKAP, Tethers Protein Kinase A at the Myofilaments

(2010) C. Amelia Sumandea et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Disruption of Protein Kinase A Localization Using a Trans-activator of Transcription (TAT)-conjugated A-kinase-anchoring Peptide Reduces Cardiac Function

(2010) Hemal H. Patel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Specificity and spatial dynamics of protein kinase A signaling organized by A-kinase-anchoring proteins

(2010) Guillaume Pidoux et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

 2-Adrenergic Receptor Redistribution in Heart Failure Changes cAMP Compartmentation

(2010) V. O. Nikolaev et al.   SCIENCE

Molecular Mechanism of Calcium Channel Regulation in the Fight-or-Flight Response

(2010) M. D. Fuller et al.   Science Signaling

Mitochondrial OPA1, apoptosis, and heart failure

(2009) Le Chen et al.   CARDIOVASCULAR RESEARCH

An Adenylyl Cyclase-mAKAPβ Signaling Complex Regulates cAMP Levels in Cardiac Myocytes

(2009) Michael S. Kapiloff et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insulin inhibits leukocyte–endothelium adherence via an Akt-NO-dependent mechanism in myocardial ischemia/reperfusion

(2009) Jia Li et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Phosphorylation and function of cardiac myosin binding protein-C in health and disease

(2009) David Barefield et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

L-type Ca2+ current in ventricular cardiomyocytes

(2009) Jean-Pierre Benitah et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Protein Kinase A Type I and Type II Define Distinct Intracellular Signaling Compartments

(2008) Giulietta Di Benedetto et al.   CIRCULATION RESEARCH

AKAP150 Is Required for Stuttering Persistent Ca 2+ Sparklets and Angiotensin II–Induced Hypertension

(2008) Manuel F. Navedo et al.   CIRCULATION RESEARCH

Proteolysis of AKAP121 regulates mitochondrial activity during cellular hypoxia and brain ischaemia

(2008) Annalisa Carlucci et al.   EMBO JOURNAL

The potential use of AKAP18δ as a drug target in heart failure patients

(2008) Birgitte Lygren et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Disruption of Protein Kinase A Interaction with A-kinase-anchoring Proteins in the Heartin Vivo

(2008) Bradley K. McConnell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AKAP-Lbc Mobilizes a Cardiac Hypertrophy Signaling Pathway

(2008) Graeme K. Carnegie et al.   MOLECULAR CELL

mAKAP Compartmentalizes Oxygen-Dependent Control of HIF-1 

(2008) W. Wong et al.   Science Signaling

Control of mitochondria dynamics and oxidative metabolism by cAMP, AKAPs and the proteasome

(2008) Annalisa Carlucci et al.   TRENDS IN CELL BIOLOGY

Calcium Cycling and Signaling in Cardiac Myocytes

(2007) Donald M. Bers   Annual Review of Physiology