Small Molecule AKAP-Protein Kinase A (PKA) Interaction Disruptors That Activate PKA Interfere with Compartmentalized cAMP Signaling in Cardiac Myocytes

Small-molecule protein-protein interaction inhibitors: Therapeutic potential in light of molecular size, chemical space, and ligand binding efficiency considerations

(2010) Peter Buchwald   IUBMB LIFE

Cardiac Troponin T, a Sarcomeric AKAP, Tethers Protein Kinase A at the Myofilaments

(2010) C. Amelia Sumandea et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Disruption of Protein Kinase A Localization Using a Trans-activator of Transcription (TAT)-conjugated A-kinase-anchoring Peptide Reduces Cardiac Function

(2010) Hemal H. Patel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of D-AKAP2:PKA RI Complex: Insights into AKAP Specificity and Selectivity

(2010) Ganapathy N. Sarma et al.   STRUCTURE

β-Adrenergic stimulation and myocardial function in the failing heart

(2009) Ali El-Armouche et al.   HEART FAILURE REVIEWS

A-kinase anchoring proteins: From protein complexes to physiology and disease

(2009) Graeme K. Carnegie et al.   IUBMB LIFE

Glycogen Synthase Kinase 3β Interaction Protein Functions as an A-kinase Anchoring Protein

(2009) Christian Hundsrucker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Cardiac IKsPotassium Channel Macromolecular Complex Includes the Phosphodiesterase PDE4D3

(2009) Cecile Terrenoire et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adenylyl Cyclase-A-kinase Anchoring Protein Complexes: The Next Dimension in cAMP Signaling

(2009) C. W. Dessauer   MOLECULAR PHARMACOLOGY

Capturing adenylyl cyclases as potential drug targets

(2009) Sandra Pierre et al.   NATURE REVIEWS DRUG DISCOVERY

AKAP-Scaffolding Proteins and Regulation of Cardiac Physiology

(2009) J. R. H. Mauban et al.   PHYSIOLOGY

The unique functions of cardiac troponin I in the control of cardiac muscle contraction and relaxation

(2008) R. John Solaro et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Protein Kinase A Type I and Type II Define Distinct Intracellular Signaling Compartments

(2008) Giulietta Di Benedetto et al.   CIRCULATION RESEARCH

Disruption of Protein Kinase A Interaction with A-kinase-anchoring Proteins in the Heartin Vivo

(2008) Bradley K. McConnell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The A-kinase anchoring protein Yotiao binds and regulates adenylyl cyclase in brain

(2008) L. A. Piggott et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Signaling through cAMP and cAMP-dependent protein kinase: Diverse strategies for drug design

(2007) Susan S. Taylor et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS