Cardiomyocytes Derived From Pluripotent Stem Cells Recapitulate Electrophysiological Characteristics of an Overlap Syndrome of Cardiac Sodium Channel Disease

High purity human-induced pluripotent stem cell-derived cardiomyocytes: electrophysiological properties of action potentials and ionic currents

(2011) Junyi Ma et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Stage-Specific Optimization of Activin/Nodal and BMP Signaling Promotes Cardiac Differentiation of Mouse and Human Pluripotent Stem Cell Lines

(2011) Steven J. Kattman et al.   Cell Stem Cell

Cardiomyocytes Obtained From Induced Pluripotent Stem Cells With Long-QT Syndrome 3 Recapitulate Typical Disease-Specific Features In Vitro

(2011) Daniela Malan et al.   CIRCULATION RESEARCH

Phenotypical Manifestations of Mutations in the Genes Encoding Subunits of the Cardiac Sodium Channel

(2011) Arthur A.M. Wilde et al.   CIRCULATION RESEARCH

Drug evaluation in cardiomyocytes derived from human induced pluripotent stem cells carrying a long QT syndrome type 2 mutation

(2011) Elena Matsa et al.   EUROPEAN HEART JOURNAL

Lentiviral Vector Design and Imaging Approaches to Visualize the Early Stages of Cellular Reprogramming

(2011) Eva Warlich et al.   MOLECULAR THERAPY

Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome

(2011) Masayuki Yazawa et al.   NATURE

Modelling the long QT syndrome with induced pluripotent stem cells

(2011) Ilanit Itzhaki et al.   NATURE

Pluripotent stem cell models of cardiac disease and their implication for drug discovery and development

(2011) Richard P. Davis et al.   TRENDS IN MOLECULAR MEDICINE

REVIEW: Sodium Channel (Dys)Function and Cardiac Arrhythmias

(2010) Carol Ann Remme et al.   Cardiovascular Therapeutics

Patient-Specific Induced Pluripotent Stem-Cell Models for Long-QT Syndrome

(2010) Alessandra Moretti et al.   NEW ENGLAND JOURNAL OF MEDICINE

Quantified proarrhythmic potential of selected human embryonic stem cell-derived cardiomyocytes

(2010) Malin K.B. Jonsson et al.   Stem Cell Research

The action potential and comparative pharmacology of stem cell-derived human cardiomyocytes

(2010) Shengde Peng et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Genetically Determined Differences in Sodium Current Characteristics Modulate Conduction Disease Severity in Mice With Cardiac Sodium Channelopathy

(2009) Carol Ann Remme et al.   CIRCULATION RESEARCH

Improvement of cardiac efficacy and safety models in drug discovery by the use of stem cell-derived cardiomyocytes

(2009) Malin KB Jonsson et al.   Expert Opinion on Drug Discovery

Functional characterization of cardiomyocytes derived from murine induced pluripotent stem cells in vitro

(2009) Alexey Kuzmenkin et al.   FASEB JOURNAL

Genetic Background Determines Magnitude of Late Sodium Current, Extent of Intracellular Na+ and Ca2+ Dysregulation, and Severity of Cardiomyopathy in Murine Sodium Channelopathy

(2009) Carol Ann Remme et al.   HEART RHYTHM

Cardiac sodium channelopathies

(2009) Ahmad S. Amin et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Cardiomyocytes from human pluripotent stem cells in regenerative medicine and drug discovery

(2009) Stefan R. Braam et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Reprogramming of murine and human somatic cells using a single polycistronic vector

(2008) B. W. Carey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cardiac Sodium Channel Overlap Syndromes: Different Faces of SCN5A Mutations

(2008) Carol Ann Remme et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Insulin Redirects Differentiation from Cardiogenic Mesoderm and Endoderm to Neuroectoderm in Differentiating Human Embryonic Stem Cells

(2007) Christian Freund et al.   STEM CELLS