Cellular Senescence, Vascular Disease, and Aging

Cardiovascular Pathology in Hutchinson-Gilford Progeria: Correlation With the Vascular Pathology of Aging

(2010) Michelle Olive et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

RETRACTED: SIRT1 Suppresses β-Amyloid Production by Activating the α-Secretase Gene ADAM10

(2010) Gizem Donmez et al.   CELL

Prelamin A Acts to Accelerate Smooth Muscle Cell Senescence and Is a Novel Biomarker of Human Vascular Aging

(2010) Cassandra D. Ragnauth et al.   CIRCULATION

SIRT1 Promotes Proliferation and Prevents Senescence Through Targeting LKB1 in Primary Porcine Aortic Endothelial Cells

(2010) Yi Zu et al.   CIRCULATION RESEARCH

Association of Marine Omega-3 Fatty Acid Levels With Telomeric Aging in Patients With Coronary Heart Disease

(2010) Ramin Farzaneh-Far   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Telomere Length and Risk of Incident Cancer and Cancer Mortality

(2010) Peter Willeit et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

SIRT1 contributes to telomere maintenance and augments global homologous recombination

(2010) Jose A. Palacios et al.   JOURNAL OF CELL BIOLOGY

Stat3-dependent acute Rantes production in vascular smooth muscle cells modulates inflammation following arterial injury in mice

(2010) Jason C. Kovacic et al.   JOURNAL OF CLINICAL INVESTIGATION

Ageing: Much ado about ageing

(2010) Heidi Ledford   NATURE

The genetics of ageing

(2010) Cynthia J. Kenyon   NATURE

Shear stress, SIRT1, and vascular homeostasis

(2010) Z. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IGF-1, oxidative stress and atheroprotection

(2010) Yusuke Higashi et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Role of Frailty in Patients With Cardiovascular Disease

(2009) Jonathan Afilalo et al.   AMERICAN JOURNAL OF CARDIOLOGY

Resveratrol attenuates mitochondrial oxidative stress in coronary arterial endothelial cells

(2009) Zoltan Ungvari et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Stress-induced senescence exaggerates postinjury neointimal formation in the old vasculature

(2009) Sheik J. Khan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Caloric Restriction and Longevity

(2009) Linda Hotchkiss Mehta et al.   Annals of the New York Academy of Sciences

Sirtuin 1 overexpression mice show a reference memory deficit, but not neuroprotection

(2009) Kenichi Kakefuda et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The role of Sirt1: At the crossroad between promotion of longevity and protection against Alzheimer's disease neuropathology

(2009) Jun Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Meta-analysis of age-related gene expression profiles identifies common signatures of aging

(2009) João Pedro de Magalhães et al.   BIOINFORMATICS

Physical Exercise Prevents Cellular Senescence in Circulating Leukocytes and in the Vessel Wall

(2009) Christian Werner et al.   CIRCULATION

Arterial Compliance in the Elderly: Its Effect on Blood Pressure Measurement and Cardiovascular Outcomes

(2009) Mary Ann Lim et al.   CLINICS IN GERIATRIC MEDICINE

Estrogenic Compounds, Estrogen Receptors and Vascular Cell Signaling in the Aging Blood Vessels

(2009) Dia Smiley et al.   CURRENT MEDICINAL CHEMISTRY

Icariin enhances neuronal survival after oxygen and glucose deprivation by increasing SIRT1

(2009) Lin Wang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Protection by tetrahydroxystilbene glucoside against cerebral ischemia: involvement of JNK, SIRT1, and NF-κB pathways and inhibition of intracellular ROS/RNS generation

(2009) Ting Wang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Neuronal SIRT1 regulates endocrine and behavioral responses to calorie restriction

(2009) D. E. Cohen et al.   GENES & DEVELOPMENT

Preventing coronary heart disease and stroke with aggressive statin therapy in older adults using a team management model

(2009) Carol M. Mason   Journal of the American Academy of Nurse Practitioners

Promoting Mechanisms of Vascular Health

(2009) Pedro R. Moreno et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Resveratrol pretreatment protects rat brain from cerebral ischemic damage via a sirtuin 1–uncoupling protein 2 pathway

(2009) D. Della-Morte et al.   NEUROSCIENCE

Telomere Diseases

(2009) Rodrigo T. Calado et al.   NEW ENGLAND JOURNAL OF MEDICINE

Ribosomal Protein S6 Kinase 1 Signaling Regulates Mammalian Life Span

(2009) C. Selman et al.   SCIENCE

Vasoprotective effects of resveratrol and SIRT1: attenuation of cigarette smoke-induced oxidative stress and proinflammatory phenotypic alterations

(2008) Anna Csiszar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Prognostic Value of Leukocyte Telomere Length in Patients With Stable Coronary Artery Disease

(2008) Ramin Farzaneh-Far et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Leukocyte Telomere Length and Carotid Artery Intimal Medial Thickness

(2008) Christopher J. O’Donnell et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Endothelium-specific overexpression of class III deacetylase SIRT1 decreases atherosclerosis in apolipoprotein E-deficient mice

(2008) Q.-j. Zhang et al.   CARDIOVASCULAR RESEARCH

Biological and Potential Therapeutic Roles of Sirtuin Deacetylases

(2008) D. M. Taylor et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Effect of intensive lipid-lowering therapy on telomere erosion in endothelial progenitor cells obtained from patients with coronary artery disease

(2008) Mamoru Satoh et al.   CLINICAL SCIENCE

Blood leucocyte telomere DNA content predicts vascular telomere DNA content in humans with and without vascular disease

(2008) W. R. W. Wilson et al.   EUROPEAN HEART JOURNAL

Sirtuin-mediated deacetylation pathway stabilizes Werner syndrome protein

(2008) Tomoaki Kahyo et al.   FEBS LETTERS

The telomerase tale in vascular aging: regulation by estrogens and nitric oxide signaling

(2008) Antonella Farsetti et al.   JOURNAL OF APPLIED PHYSIOLOGY

Regulation of WRN Protein Cellular Localization and Enzymatic Activities by SIRT1-mediated Deacetylation

(2008) Kai Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sirtuin 1 Reduction Parallels the Accumulation of Tau in Alzheimer Disease

(2008) Carl Julien et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Resveratrol attenuates ischemic brain damage in the delayed phase after stroke and induces messenger RNA and protein express for angiogenic factors

(2008) WenPeng Dong et al.   JOURNAL OF VASCULAR SURGERY

SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin

(2008) Eriko Michishita et al.   NATURE

Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing

(2008) Paola Scaffidi et al.   NATURE CELL BIOLOGY

Sirt1 contributes critically to the redox-dependent fate of neural progenitors

(2008) Timour Prozorovski et al.   NATURE CELL BIOLOGY

Opposing Effects of Sirtuins on Neuronal Survival: SIRT1-Mediated Neuroprotection Is Independent of Its Deacetylase Activity

(2008) Jason A. Pfister et al.   PLoS One

A farnesyltransferase inhibitor prevents both the onset and late progression of cardiovascular disease in a progeria mouse model

(2008) B. C. Capell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Resident vascular progenitor cells: An emerging role for non-terminally differentiated vessel-resident cells in vascular biology

(2008) Jason C. Kovacic et al.   Stem Cell Research

The effects of resveratrol on vasospasm after experimental subarachnoidal hemorrhage in rats

(2008) Alper Karaoglan et al.   SURGICAL NEUROLOGY

Endothelial Progenitor Cells, Angioblasts, and Angiogenesis—Old Terms Reconsidered From a Current Perspective

(2008) Jason C. Kovacic et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Exercise Training Promotes SIRT1 Activity in Aged Rats

(2007) Nicola Ferrara et al.   REJUVENATION RESEARCH