Echocardiographic Markers of Elevated Pulmonary Pressure and Left Ventricular Diastolic Dysfunction Are Associated With Exercise Intolerance in Adults and Adolescents With Homozygous Sickle Cell Anemia in the United States and United Kingdom

Hospitalization for pain in patients with sickle cell disease treated with sildenafil for elevated TRV and low exercise capacity

(2011) R. F. Machado et al.   BLOOD

Improvements in haemolysis and indicators of erythrocyte survival do not correlate with acute vaso-occlusive crises in patients with sickle cell disease: a phase III randomized, placebo-controlled, double-blind study of the gardos channel blocker senicapo

(2011) Kenneth I. Ataga et al.   BRITISH JOURNAL OF HAEMATOLOGY

Effect of Obesity and Overweight on Left Ventricular Diastolic Function

(2011) Cesare Russo et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Sickle cell anemia pathophysiology: Back to the data

(2010) James R. Eckman et al.   AMERICAN JOURNAL OF HEMATOLOGY

Reconstructing sickle cell disease: A data-based analysis of the “hyperhemolysis paradigm” for pulmonary hypertension from the perspective of evidence-based medicine

(2010) Robert P. Hebbel   AMERICAN JOURNAL OF HEMATOLOGY

Pulmonary hypertension in thalassemia

(2010) Claudia R. Morris et al.   Annals of the New York Academy of Sciences

Pulmonary hypertension and nitric oxide depletion in sickle cell disease

(2010) H. F. Bunn et al.   BLOOD

Pulmonary hypertension and NO in sickle cell

(2010) M. T. Gladwin et al.   BLOOD

High levels of placenta growth factor in sickle cell disease promote pulmonary hypertension

(2010) N. Sundaram et al.   BLOOD

Pulmonary hypertension in sickle cell disease children under 10 years of age

(2010) Raffaella Colombatti et al.   BRITISH JOURNAL OF HAEMATOLOGY

Elevated tricuspid regurgitation velocity and decline in exercise capacity over 22 months of follow up in children and adolescents with sickle cell anemia

(2010) V. R. Gordeuk et al.   HAEMATOLOGICA

Relationship of erythropoietin, fetal hemoglobin, and hydroxyurea treatment to tricuspid regurgitation velocity in children with sickle cell disease

(2009) V. R. Gordeuk et al.   BLOOD

Elevated tricuspid regurgitant jet velocity in children and adolescents with sickle cell disease: association with hemolysis and hemoglobin oxygen desaturation

(2009) C. P. Minniti et al.   HAEMATOLOGICA

Left Ventricular Function and Exercise Capacity

(2009) Jasmine Grewal   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Recommendations for the Evaluation of Left Ventricular Diastolic Function by Echocardiography

(2009) Sherif F. Nagueh et al.   JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY

Angiogenic and Inflammatory Markers of Cardiopulmonary Changes in Children and Adolescents with Sickle Cell Disease

(2009) Xiaomei Niu et al.   PLoS One

Pulmonary arterial hypertension and left‐sided heart disease in sickle cell disease: Clinical characteristics and association with soluble adhesion molecule expression

(2008) Elizabeth S. Klings et al.   AMERICAN JOURNAL OF HEMATOLOGY

The increase in pulmonary arterial pressure caused by hypoxia depends on iron status

(2008) Thomas G. Smith et al.   JOURNAL OF PHYSIOLOGY-LONDON