High levels of placenta growth factor in sickle cell disease promote pulmonary hypertension

A novel human gamma-globin gene vector for genetic correction of sickle cell anemia in a humanized sickle mouse model: critical determinants for successful correction

(2009) A. Perumbeti et al.   BLOOD

Placenta growth factor in sickle cell disease: association with hemolysis and inflammation

(2009) J. E. Brittain et al.   BLOOD

Pleiotropic effects of intravascular haemolysis on vascular homeostasis

(2009) Gregory J. Kato et al.   BRITISH JOURNAL OF HAEMATOLOGY

Elevated tricuspid regurgitant jet velocity in children and adolescents with sickle cell disease: association with hemolysis and hemoglobin oxygen desaturation

(2009) C. P. Minniti et al.   HAEMATOLOGICA

Genotoxic Potential of Lineage-specific Lentivirus Vectors Carrying the β-Globin Locus Control Region

(2009) Paritha I Arumugam et al.   MOLECULAR THERAPY

Pulmonary arterial hypertension and left‐sided heart disease in sickle cell disease: Clinical characteristics and association with soluble adhesion molecule expression

(2008) Elizabeth S. Klings et al.   AMERICAN JOURNAL OF HEMATOLOGY

Placenta growth factor augments endothelin-1 and endothelin-B receptor expression via hypoxia-inducible factor-1 

(2008) N. Patel et al.   BLOOD

Coagulation activation and inflammation in sickle cell disease-associated pulmonary hypertension

(2008) K. I. Ataga et al.   HAEMATOLOGICA

Endothelin receptor antagonism prevents hypoxia-induced mortality and morbidity in a mouse model of sickle-cell disease

(2008) Nathalie Sabaa et al.   JOURNAL OF CLINICAL INVESTIGATION

Pulmonary Hypertension Associated with Sickle Cell Disease: Pathophysiology and Rationale for Treatment

(2008) Raymond L. Benza   LUNG