Article
Chemistry, Multidisciplinary
Ku Youn Baik, Hyun Jo, Se Hoon Ki, Gi-Chung Kwon, Guangsup Cho
Summary: The efficiency of simultaneous treatment of cold atmospheric pressure plasma jet (CAP) and hydrogen peroxide (H2O2) was studied for bacterial disinfection. The combination of CAP with H2O2 showed dramatic synergistic effects in killing bacteria by enhancing reactive species transportation and intracellular oxidation. The non-toxic byproducts of CAP and H2O2 make their combination a promising candidate for clinical applications.
APPLIED SCIENCES-BASEL
(2023)
Article
Biochemistry & Molecular Biology
Dennis Feibel, Judith Golda, Julian Held, Peter Awakowicz, Volker von der Gathen, Christoph V. Suschek, Christian Oplaender, Florian Jansen
Summary: By adjusting the gas flow, the micro-scaled Atmospheric Pressure Plasma Jet (mu APPJ) can produce different levels of reactive oxygen or nitrogen species (ROS or RNS), leading to varying effects on buffers and human skin fibroblasts (hsFB). The toxicity of CAP treatment on hsFB is correlated with the accumulated H2O2 concentration.
Article
Biochemistry & Molecular Biology
Charlotta Bengtson, Annemie Bogaerts
Summary: Researchers developed a mathematical model to describe cellular response to cold atmospheric plasma and plasma-treated liquids, finding that selectivity and synergistic effects can be used to quantify cell susceptibility towards exogenous H2O2.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Biotechnology & Applied Microbiology
Won-Jae Song, Dong-Hyun Kang
Summary: The study evaluated the efficacy of VHPV in reducing foodborne pathogens in black and red pepper without causing color changes. Results showed that VHPV treatment significantly decreased pathogen quantities in both types of pepper, with minimal impact on color. This study highlights the potential of VHPV as a method for pathogen reduction in food products.
JOURNAL OF APPLIED MICROBIOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Maho Yagi-Utsumi, Tomohiro Tanaka, Yoko Otsubo, Akira Yamashita, Shinji Yoshimura, Motohiro Nishida, Koichi Kato
Summary: The study reveals that cold atmospheric plasma can affect the amyloidogenic protein Aβ associated with Alzheimer's disease by selectively oxidizing certain amino acid residues, inhibiting its fibril formation. This provides insights into potential novel applications of CAP.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Food Science & Technology
Yijie Zhao, Lele Shao, Lihong Jia, Bo Zou, Ruitong Dai, Xingmin Li, Fei Jia
Summary: This study investigated the effects of cold atmospheric plasma on Pseudomonas aeruginosa and its inactivation mechanism. The results showed that air-CAP had better inactivation capacity than nitrogen-CAP, and the mechanism involved damage to cell morphology, changes in membrane permeability, disruption of intracellular ionic equilibrium, and lipid peroxidation.
INNOVATIVE FOOD SCIENCE & EMERGING TECHNOLOGIES
(2022)
Article
Chemistry, Multidisciplinary
Rakesh Ruchel Khanikar, Monalisa Kalita, Parismita Kalita, Bhaswati Kashyap, Santanu Das, Mojibur R. Khan, Heremba Bailung, Kamatchi Sankaranarayanan
Summary: This study demonstrates that cold atmospheric pressure plasma treatment can deactivate the SARS-CoV-2 spike protein and degrade the RNA of the virus. The deactivation of spike protein binding is correlated with the higher concentration of hydrogen peroxide formation due to the interaction with reactive oxygen species in the plasma. This green process, using noble gases to generate reactive oxygen species, shows potential for designing disinfection systems and biomedical applications.
Article
Multidisciplinary Sciences
Lea Miebach, Eric Freund, Stefan Horn, Felix Niessner, Sanjeev Kumar Sagwal, Thomas von Woedtke, Steffen Emmert, Klaus-Dieter Weltmann, Ramona Clemen, Anke Schmidt, Torsten Gerling, Sander Bekeschus
Summary: Recent research focused on the potential of cold physical plasma in cancer therapy, with the study aiming to use a newly designed dual-jet neon plasma source for treating colorectal cancer cells. Results showed time-dependent generation of ROS/RNS inducing oxidation, growth retardation, and cell death in 3D tumor spheroids. The plasma devices (V)jet and kINPen exhibited differing effects on tumor growth and immunogenic cell death markers in in vitro and in vivo models. The study highlights the importance of evaluating optimal discharges for plasma cancer treatment based on plasma device-specific action on cancer cells.
SCIENTIFIC REPORTS
(2021)
Article
Chemistry, Multidisciplinary
Je-Chuang Wang, Wen-Chien Huang, Ken-Fa Cheng, Nien-Tung Liu, Kuo-Hui Wu
Summary: The study evaluated the efficacy of expired disinfectants in deactivating biological and chemical toxins on building material surfaces. The results showed that despite being past their expiration dates, the disinfectants had high effectiveness in deactivating biological toxins.
Article
Physics, Applied
Zhenping Zou, Rui Han, Chen Lu, Zilan Xiong
Summary: This study proposes a digital colorimetry-based method for quantifying chemistries in plasma-activated water using smartphones and specialized software. Specialized curve-fitting strategies were developed for data processing. Results showed better performance and simplified operation compared to UV-Vis spectrometry, and the proposed method can be integrated with a PAW generator design.
PLASMA PROCESSES AND POLYMERS
(2021)
Article
Physics, Applied
Seyedehneda Siadati, Maria Pet'kova, Ali Jamaati Kenari, Stanislav Kyzek, Eliska Galova, Anna Zahoranova
Summary: Non-thermal atmospheric pressure plasmas have demonstrated effective inactivation of microorganisms, with Argon plasma jet found to have strong action on various yeast species. The most effective treatment was direct plasma exposure in distilled water, which led to significant reductions in yeast survival rates. The presence of high concentrations of reactive oxygen and nitrogen species in the plasma system, as well as changes in conductivity and pH of treated water, contributed to the synergistic yeast inactivation effects.
JOURNAL OF PHYSICS D-APPLIED PHYSICS
(2021)
Article
Physics, Applied
Hannah L. Wapshott-Stehli, Brayden G. Myers, Maria J. Herrera Quesada, Amy Grunden, Katharina Stapelmann
Summary: Enzymes like OleT(JE) are commonly used in the industry, but the presence of hydrogen peroxide can cause overoxidation. This study explores the use of an atmospheric pressure plasma jet to generate hydrogen peroxide slowly in situ, providing a reliable reaction mediator for OleT(JE) activity.
PLASMA PROCESSES AND POLYMERS
(2022)
Article
Chemistry, Multidisciplinary
Jacob Manzi, Ariel E. E. Weltner, Tony Varghese, Nicholas McKibben, Mia Busuladzic-Begic, David Estrada, Harish Subbaraman
Summary: This paper demonstrates the use of plasma-jet printing (PJP) to deposit thermoelectric nanoflakes onto flexible substrates at room temperature, with substantial improvements in material adhesion and flexibility observed. The printed films exhibit electrical conductivity of 2.5 x 10(3) S m(-1) and a power factor of 70 mu W m(-1) K-2 at room temperature. This advancement in plasma jet printing promotes not only the development of energy harvesting but also large-scale flexible electronics and sensors for space and commercial applications.
Article
Multidisciplinary Sciences
Rasool Erfani, Cameron Carmichael, Thea Sofokleous, Qiuyu Wang
Summary: Plasma therapy is an exciting and novel cancer treatment method that can be influenced by treatment time and different parameters. Changing the polarity of the reactor can alter the plasma discharge regime, thereby directly affecting the treatment effectiveness. This treatment method can induce cell death, which is not completely counteracted by N-acetyl cysteine. Gene expression analysis also identified key genes associated with plasma-induced cell death.
SCIENTIFIC REPORTS
(2022)
Article
Chemistry, Physical
Lipeng Zhai, Zhipeng Xie, Cheng-Xing Cui, Xiubei Yang, Qing Xu, Xiating Ke, Minghao Liu, Ling-Bo Qu, Xiong Chen, Liwei Mi
Summary: Covalent organic frameworks (COFs) are a suitable template for photocatalytic H2O2 synthesis due to their tunable chemical structures and semiconductor properties. However, the photoactivity of COFs is still suboptimal due to inefficient charge generation, fast recombination of photogenerated charges, and limited electron transport. In this study, triazine and acetylene units were integrated into COFs, leading to efficient charge separation, suppressed charge recombination, and enhanced electron transport. Experimental and computational results demonstrated that triazine and acetylene units synergistically promoted H2O2 synthesis through a two-electron pathway.
CHEMISTRY OF MATERIALS
(2022)