What can we learn from virus in designing nonviral gene vectors

Vitamin B12-Mediated Transport: A Potential Tool for Tumor Targeting of Antineoplastic Drugs and Imaging Agents

(2012) Yashwant Gupta et al.   CRITICAL REVIEWS IN THERAPEUTIC DRUG CARRIER SYSTEMS

Gene therapy finds its niche

(2011) Cormac Sheridan   NATURE BIOTECHNOLOGY

Hybrids of Nonviral Vectors for Gene Delivery

(2010) Shubiao Zhang et al.   BIOCONJUGATE CHEMISTRY

Self-Assembled Terplexes for Targeted Gene Delivery with Improved Transfection

(2010) Qiao Zhang et al.   BIOCONJUGATE CHEMISTRY

Efficient Gene Transfection by Histidine-Modified Chitosan through Enhancement of Endosomal Escape

(2010) Kai-Ling Chang et al.   BIOCONJUGATE CHEMISTRY

Construction of a Star-Shaped Copolymer as a Vector for FGF Receptor-Mediated Gene Delivery In Vitro and In Vivo

(2010) Da Li et al.   BIOMACROMOLECULES

Polycation/DNA complexes coated with oligonucleotides for gene delivery

(2010) Yi-Chen Chung et al.   BIOMATERIALS

Degradable, pH-sensitive, membrane-destabilizing, comb-like polymers for intracellular delivery of nucleic acids

(2010) Yen-Ling Lin et al.   BIOMATERIALS

DNA/polyethyleneimine/hyaluronic acid small complex particles and tumor suppression in mice

(2010) Tomoko Ito et al.   BIOMATERIALS

Enhanced gene transfection and serum stability of polyplexes by PDMAEMA-polysulfobetaine diblock copolymers

(2010) Fengying Dai et al.   BIOMATERIALS

Responsive polyelectrolyte complexes for triggered release of nucleic acid therapeutics

(2010) Mahmoud Soliman et al.   CHEMICAL COMMUNICATIONS

Gene delivery by lipoplexes and polyplexes

(2010) Conchita Tros de Ilarduya et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Nanoparticles for ex vivo siRNA delivery to dendritic cells for cancer vaccines: Programmed endosomal escape and dissociation☆

(2010) Hidetaka Akita et al.   JOURNAL OF CONTROLLED RELEASE

Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia

(2010) Marina Cavazzana-Calvo et al.   NATURE

Learning from the Viral Journey: How to Enter Cells and How to Overcome Intracellular Barriers to Reach the Nucleus

(2009) Diky Mudhakir et al.   AAPS Journal

Nonviral Gene Delivery: Principle, Limitations, and Recent Progress

(2009) Mohammed S. Al-Dosari et al.   AAPS Journal

Transcriptionally regulated, prostate-targeted gene therapy for prostate cancer

(2009) Yi Lu   ADVANCED DRUG DELIVERY REVIEWS

Targeted Gene Delivery Mediated by Folate-polyethylenimine-block-poly(ethylene glycol) with Receptor Selectivity

(2009) Han Cheng et al.   BIOCONJUGATE CHEMISTRY

Nuclear drug delivery to target tumour cells

(2009) Kylie M. Wagstaff et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Pancreatic cancer: gene therapy approaches and gene delivery systems

(2009) Jin Xu et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Viral-based gene delivery and regulated gene expression for targeted cancer therapy

(2009) Yi Lu et al.   Expert Opinion on Drug Delivery

Phase-I clinical trial of IL-12 plasmid/lipopolymer complexes for the treatment of recurrent ovarian cancer

(2009) K Anwer et al.   GENE THERAPY

Progress and prospects: immune responses to viral vectors

(2009) S Nayak et al.   GENE THERAPY

Clinical Adenoviral Gene Therapy for Prostate Cancer

(2009) Ellen Schenk et al.   HUMAN GENE THERAPY

Efficient polyethylenimine-mediated gene delivery proceeds via a caveolar pathway in HeLa cells

(2009) Nathan P. Gabrielson et al.   JOURNAL OF CONTROLLED RELEASE

Missing pieces in understanding the intracellular trafficking of polycation/DNA complexes

(2009) You-Yeon Won et al.   JOURNAL OF CONTROLLED RELEASE

Tumor regression after systemic administration of a novel tumor-targeted gene delivery system carrying a therapeutic plasmid DNA

(2009) Swati Koppu et al.   JOURNAL OF CONTROLLED RELEASE

A Phase I Study of Telomerase-specific Replication Competent Oncolytic Adenovirus (Telomelysin) for Various Solid Tumors

(2009) John Nemunaitis et al.   MOLECULAR THERAPY

Gene therapy for red–green colour blindness in adult primates

(2009) Katherine Mancuso et al.   NATURE

Investigation of the Cause of Death in a Gene-Therapy Trial

(2009) Karen M. Frank et al.   NEW ENGLAND JOURNAL OF MEDICINE

Non-viral nanosystems for systemic siRNA delivery

(2009) Stephanie David et al.   PHARMACOLOGICAL RESEARCH

Viral vectors for neurotrophic factor delivery: A gene therapy approach for neurodegenerative diseases of the CNS

(2009) Seung T. Lim et al.   PHARMACOLOGICAL RESEARCH

Hematopoietic Stem Cell Gene Therapy with a Lentiviral Vector in X-Linked Adrenoleukodystrophy

(2009) N. Cartier et al.   SCIENCE

Virion-Mimicking Nanocapsules from pH-Controlled Hierarchical Self-Assembly for Gene Delivery

(2008) Peisheng Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Polycation nanostructured lipid carrier, a novel nonviral vector constructed with triolein for efficient gene delivery

(2008) Zhiwen Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Synthesis and characterization of folate-PEG-grafted-hyperbranched-PEI for tumor-targeted gene delivery

(2008) Bing Liang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Systematic Investigation of Polyamidoamine Dendrimers Surface-Modified with Poly(ethylene glycol) for Drug Delivery Applications: Synthesis, Characterization, and Evaluation of Cytotoxicity

(2008) Yoonkyung Kim et al.   BIOCONJUGATE CHEMISTRY

A Smart Nanoassembly Consisting of Acid-Labile Vinyl Ether PEG−DOPE and Protamine for Gene Delivery: Preparation and in Vitro Transfection

(2008) Zhenghong Xu et al.   BIOMACROMOLECULES

Progress in developing cationic vectors for non-viral systemic gene therapy against cancer

(2008) Marie Morille et al.   BIOMATERIALS

Highly efficient in vivo gene transfection by plasmid/PEI complexes coated by anionic PEG derivatives bearing carboxyl groups and RGD peptide

(2008) Mitsuko Sakae et al.   BIOMEDICINE & PHARMACOTHERAPY

The Receptor-Mediated Endocytosis of Nonspherical Particles

(2008) P. Decuzzi et al.   BIOPHYSICAL JOURNAL

Hyaluronic acid–polyethyleneimine conjugate for target specific intracellular delivery of siRNA

(2008) Ge Jiang et al.   BIOPOLYMERS

Nonviral Vectors for Gene Delivery

(2008) Meredith A. Mintzer et al.   CHEMICAL REVIEWS

Gene Therapy Using Adeno-Associated Virus Vectors

(2008) S. Daya et al.   CLINICAL MICROBIOLOGY REVIEWS

Hepatitis B virus surface antigen impairs myeloid dendritic cell function: a possible immune escape mechanism of hepatitis B virus

(2008) Marjoleine L. Op den Brouw et al.   IMMUNOLOGY

Mannosylated polyethylenimine coupled mesoporous silica nanoparticles for receptor-mediated gene delivery

(2008) In Young Park et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Recombinant alpha-fetoprotein C-terminal fragment: The new recombinant vector for targeted delivery

(2008) Galina A. Posypanova et al.   JOURNAL OF DRUG TARGETING

The effect of endosomal escape peptides onin vitrogene delivery of polyethylene glycol-based vehicles

(2008) Nicole M. Moore et al.   JOURNAL OF GENE MEDICINE

PEG-Detachable Polyplex Micelles Based on Disulfide-Linked Block Catiomers as Bioresponsive Nonviral Gene Vectors

(2008) Seiji Takae et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Intracellular delivery of an anionic antisense oligonucleotide via receptor-mediated endocytosis

(2008) Md Rowshon Alam et al.   NUCLEIC ACIDS RESEARCH

pH-dependent swelling of hydrogels containing highly branched polyamine macromonomers

(2008) Burcu Unal et al.   POLYMER

Multifunctional envelope-type nano device (MEND) as a non-viral gene delivery system

(2007) Kentaro Kogure et al.   ADVANCED DRUG DELIVERY REVIEWS

Nanoconjugate based on polymalic acid for tumor targeting

(2007) Julia Y. Ljubimova et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Poly(ethylene glycol)-block-polyethylenimine copolymers as carriers for gene delivery: Effects of PEG molecular weight and PEGylation degree

(2007) Xuan Zhang et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A