TNFR2 Deficiency Acts in Concert with Gut Microbiota To Precipitate Spontaneous Sex-Biased Central Nervous System Demyelinating Autoimmune Disease

Variation in the Human Immune System Is Largely Driven by Non-Heritable Influences

(2015) Petter Brodin et al.   CELL

Sexual dimorphism in autoimmunity

(2015) Kira Rubtsova et al.   JOURNAL OF CLINICAL INVESTIGATION

Transmembrane TNF–TNFR2 Impairs Th17 Differentiation by PromotingIl2Expression

(2015) Patrick G. Miller et al.   JOURNAL OF IMMUNOLOGY

Gut Microbiota in Multiple Sclerosis

(2015) Brandi L. Cantarel et al.   JOURNAL OF INVESTIGATIVE MEDICINE

Vertically transmitted faecal IgA levels determine extra-chromosomal phenotypic variation

(2015) Clara Moon et al.   NATURE

Specific gut microbiota features and metabolic markers in postmenopausal women with obesity

(2015) L K Brahe et al.   Nutrition & Diabetes

Pathogenic aquaporin-4 reactive T cells are sufficient to induce mouse model of neuromyelitis optica

(2015) Melina V Jones et al.   Acta Neuropathologica Communications

Enhanced sphingosine-1-phosphate receptor 2 expression underlies female CNS autoimmunity susceptibility

(2014) Lillian Cruz-Orengo et al.   JOURNAL OF CLINICAL INVESTIGATION

Biphasic Regulation of Il2 Transcription in CD4+ T Cells: Roles for TNF-  Receptor Signaling and Chromatin Structure

(2014) S. C. McKarns et al.   JOURNAL OF IMMUNOLOGY

Altered Expression of Oligodendrocyte and Neuronal Marker Genes Predicts the Clinical Onset of Autoimmune Encephalomyelitis and Indicates the Effectiveness of Multiple Sclerosis-Directed Therapeutics

(2014) M. Evangelidou et al.   JOURNAL OF IMMUNOLOGY

Antibody-Mediated Inhibition of TNFR1 Attenuates Disease in a Mouse Model of Multiple Sclerosis

(2014) Sarah K. Williams et al.   PLoS One

Gut Microbiome in Down Syndrome

(2014) Elena Biagi et al.   PLoS One

Neuromyelitis Optica Spectrum Disorders With Aquaporin-4 and Myelin-Oligodendrocyte Glycoprotein Antibodies

(2014) Joanna Kitley et al.   JAMA Neurology

Gender Bias in Autoimmunity Is Influenced by Microbiota

(2013) Leonid Yurkovetskiy et al.   IMMUNITY

Human Gut Microbiota Changes Reveal the Progression of Glucose Intolerance

(2013) Xiuying Zhang et al.   PLoS One

Fecal Microbiota and Metabolome of Children with Autism and Pervasive Developmental Disorder Not Otherwise Specified

(2013) Maria De Angelis et al.   PLoS One

Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity

(2013) A. Everard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sex Differences in the Gut Microbiome Drive Hormone-Dependent Regulation of Autoimmunity

(2013) J. G. M. Markle et al.   SCIENCE

Commensal gut flora and brain autoimmunity: a love or hate affair?

(2012) Kerstin Berer et al.   ACTA NEUROPATHOLOGICA

Aquaporin 4-specific T cells in neuromyelitis optica exhibit a Th17 bias and recognizeClostridiumABC transporter

(2012) Michel Varrin-Doyer et al.   ANNALS OF NEUROLOGY

Early life treatment with vancomycin propagates Akkermansia muciniphila and reduces diabetes incidence in the NOD mouse

(2012) C. H. F. Hansen et al.   DIABETOLOGIA

Decreased abundance ofFaecalibacterium prausnitziiin the gut microbiota of Crohn's disease

(2012) Takehide Fujimoto et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis

(2012) Adam P. Gregory et al.   NATURE

PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells

(2012) Daniela Cipolletta et al.   NATURE

PrimerProspector: de novo design and taxonomic analysis of barcoded polymerase chain reaction primers

(2011) William A. Walters et al.   BIOINFORMATICS

FLASH: fast length adjustment of short reads to improve genome assemblies

(2011) T. Magoc et al.   BIOINFORMATICS

The tumour necrosis factor/TNF receptor superfamily: therapeutic targets in autoimmune diseases

(2011) D. S. Vinay et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Natural but Not Inducible Regulatory T Cells Require TNF-  Signaling for In Vivo Function

(2011) W. J. Housley et al.   JOURNAL OF IMMUNOLOGY

Sex Differences in Response to Anti-Tumor Necrosis Factor Therapy in Early and Established Rheumatoid Arthritis -- Results from the DANBIO Registry

(2011) D. JAWAHEER et al.   JOURNAL OF RHEUMATOLOGY

Secretory IgA's complex roles in immunity and mucosal homeostasis in the gut

(2011) N J Mantis et al.   Mucosal Immunology

Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination

(2011) Kerstin Berer et al.   NATURE

Crosstalk between B lymphocytes, microbiota and the intestinal epithelium governs immunity versus metabolism in the gut

(2011) Natalia Shulzhenko et al.   NATURE MEDICINE

The Starting Lineup: Key Microbial Players in Intestinal Immunity and Homeostasis

(2011) Nicola C. Reading et al.   Frontiers in Microbiology

Modulation of Mucosal Immune Response, Tolerance, and Proliferation in Mice Colonized by the Mucin-Degrader Akkermansia muciniphila

(2011) Muriel Derrien et al.   Frontiers in Microbiology

Predictors of response to methotrexate in early DMARD naive rheumatoid arthritis: results from the initial open-label phase of the SWEFOT trial

(2010) S. Saevarsdottir et al.   ANNALS OF THE RHEUMATIC DISEASES

Th1 versus Th17: Are T cell cytokines relevant in multiple sclerosis?

(2010) Amy E. Lovett-Racke et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Co-expression of TNFR2 and CD25 identifies more of the functional CD4+FOXP3+regulatory T cells in human peripheral blood

(2010) Xin Chen et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

TNF receptor 2 pathway: drug target for autoimmune diseases

(2010) Denise Faustman et al.   NATURE REVIEWS DRUG DISCOVERY

A Novel Probiotic Mixture Exerts a Therapeutic Effect on Experimental Autoimmune Encephalomyelitis Mediated by IL-10 Producing Regulatory T Cells

(2010) Shahram Lavasani et al.   PLoS One

Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis

(2010) Y. K. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota

(2010) J. L. Round et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Global patterns of 16S rRNA diversity at a depth of millions of sequences per sample

(2010) J. G. Caporaso et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Single, Early Magnetic Resonance Imaging Study in the Diagnosis of Multiple Sclerosis

(2009) Àlex Rovira et al.   ARCHIVES OF NEUROLOGY

Claudin-5 as a Novel Estrogen Target in Vascular Endothelium

(2009) Malgorzata Burek et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Lack of TNFR2 expression by CD4+T cells exacerbates experimental colitis

(2009) Johanna Dayer Schneider et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The Key Role of Segmented Filamentous Bacteria in the Coordinated Maturation of Gut Helper T Cell Responses

(2009) Valérie Gaboriau-Routhiau et al.   IMMUNITY

Spontaneous relapsing-remitting EAE in the SJL/J mouse: MOG-reactive transgenic T cells recruit endogenous MOG-specific B cells

(2009) Bernadette Pöllinger et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Sex: a major predictor of remission as measured by 28-joint Disease Activity Score (DAS28) in early rheumatoid arthritis?

(2008) H Makinen et al.   ANNALS OF THE RHEUMATIC DISEASES

Mechanisms of Sex Differences in TNFR2-Mediated Cardioprotection

(2008) M. Wang et al.   CIRCULATION

Effects ofBifidobacterium animalisadministered during lactation on allergic and autoimmune responses in rodents

(2008) J. Ezendam et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

SpecificLactobacillusspecies differentially activate Toll-like receptors and downstream signals in dendritic cells

(2008) Mansour Mohamadzadeh et al.   Expert Review of Vaccines

Induction and effector functions of TH17 cells

(2008) Estelle Bettelli et al.   NATURE

Endogenous or exogenous oligodendrocytes for remyelination

(2007) W.F. Blakemore et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES