Modeling the Interaction between Dendrimers and Nucleic Acids: a Molecular Perspective through Hierarchical Scales

Dendrimers and dendrons for siRNA binding: computational insights

(2015) G.M. Pavan et al.   JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

Molecular modeling of polynucleotide complexes

(2014) Deniz Meneksedag-Erol et al.   BIOMATERIALS

Protein-Triggered Supramolecular Disassembly: Insights Based on Variations in Ligand Location in Amphiphilic Dendrons

(2014) Diego Amado Torres et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Monte-Carlo simulations of PAMAM dendrimer–DNA interactions

(2014) Shi Yu et al.   Soft Matter

Structure and Shape Effects of Molecular Glue on Supramolecular Tubulin Assemblies

(2013) Matteo Garzoni et al.   ACS Nano

Efficient Dendrimer–DNA Complexation and Gene Delivery Vector Properties of Nitrogen-Core Poly(propyl ether imine) Dendrimer in Mammalian Cells

(2013) Abirami Lakshminarayanan et al.   BIOCONJUGATE CHEMISTRY

A molecular dynamics simulation study on the effect of lipid substitution on polyethylenimine mediated siRNA complexation

(2013) Chongbo Sun et al.   BIOMATERIALS

Computational design principles for the discovery of bioactive dendrimers: [s]-triazines and other examples

(2013) Eric E Simanek et al.   Expert Opinion on Drug Discovery

Photoclickable Dendritic Molecular Glue: Noncovalent-to-Covalent Photochemical Transformation of Protein Hybrids

(2013) Noriyuki Uchida et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Computational Investigations of a Peptide-Modified Dendrimer Interacting with Lipid Membranes

(2013) Chen-kun Tu et al.   MACROMOLECULAR RAPID COMMUNICATIONS

DNA Condensation by Partially Acetylated Poly(amido amine) Dendrimers: Effects of Dendrimer Charge Density on Complex Formation

(2013) Shi Yu et al.   MOLECULES

Combining metadynamics simulation and experiments to characterize dendrimers in solution

(2013) Giovanni M. Pavan et al.   Soft Matter

Targeting the Blind Spot of Polycationic Nanocarrier-Based siRNA Delivery

(2012) Mengyao Zheng et al.   ACS Nano

Probing the Effects of Lipid Substitution on Polycation Mediated DNA Aggregation: A Molecular Dynamics Simulations Study

(2012) Chongbo Sun et al.   BIOMACROMOLECULES

Theoretical and computational studies of dendrimers as delivery vectors

(2012) Wen-de Tian et al.   CHEMICAL SOCIETY REVIEWS

Role of Generation, Architecture, pH and Ionic Strength on Successful siRNA Delivery and Transfection by Hybrid PPV-PAMAM Dendrimers

(2012) G. M. Pavan et al.   CURRENT MEDICINAL CHEMISTRY

Interaction of nucleic acids with carbon nanotubes and dendrimers

(2012) Bidisha Nandy et al.   JOURNAL OF BIOSCIENCES

Force Biased Molecular Dynamics Simulation Study of Effect of Dendrimer Generation on Interaction with DNA

(2012) Bidisha Nandy et al.   Journal of Chemical Theory and Computation

Molecular Dynamics Simulations for Complexation of DNA with 2 kDa PEI Reveal Profound Effect of PEI Architecture on Complexation

(2012) Chongbo Sun et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Attractive Hydration Forces in DNA–Dendrimer Interactions on the Nanometer Scale

(2012) Maria Mills et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Experimental and Computational Evidence for an Inversion in Guest Capacity in High-Generation Triazine Dendrimer Hosts

(2012) Jongdoo Lim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ion-Selective Controlled Assembly of Dendrimer-Based Functional Nanofibers and Their Ionic-Competitive Disassembly

(2012) Matteo Garzoni et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Antitumor Activity and Molecular Dynamics Simulations of Paclitaxel-Laden Triazine Dendrimers

(2012) Jongdoo Lim et al.   MOLECULAR PHARMACEUTICS

Nanotechnology: Shape matters

(2012) Sharon C. Glotzer   NATURE

A simple and rapid nonviral approach to efficiently transfect primary tissue–derived cells using polyethylenimine

(2012) Charlie Yu Ming Hsu et al.   Nature Protocols

Insights into the endosomal escape mechanism via investigation of dendrimer–membrane interactions

(2012) Wen-de Tian et al.   Soft Matter

Molecular Dynamics Simulations of PEI Mediated DNA Aggregation

(2011) Chongbo Sun et al.   BIOMACROMOLECULES

Elucidating the molecular mechanism of PAMAM–siRNA dendriplex self-assembly: Effect of dendrimer charge density

(2011) Linda B. Jensen et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Catalytic Chameleon Dendrimers

(2011) M. Shema-Mizrachi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Degradable Self-Assembling Dendrons for Gene Delivery: Experimental and Theoretical Insights into the Barriers to Cellular Uptake

(2011) Anna Barnard et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dendritic effects: dependency of dendritic nano-periodic property patterns on critical nanoscale design parameters (CNDPs)

(2011) Donald A. Tomalia   NEW JOURNAL OF CHEMISTRY

Adhesion Effects of a Guanidinium Ion Appended Dendritic “Molecular Glue” on the ATP-Driven Sliding Motion of Actomyosin

(2010) Kou Okuro et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Computational Insights into the Interactions between DNA and siRNA with “Rigid” and “Flexible” Triazine Dendrimers

(2010) Giovanni M. Pavan et al.   BIOMACROMOLECULES

Microscopic Basis for the Mesoscopic Extensibility of Dendrimer-Compacted DNA

(2010) Maria Mills et al.   BIOPHYSICAL JOURNAL

Quantifying the Effect of Surface Ligands on Dendron-DNA Interactions: Insights into Multivalency through a Combined Experimental and Theoretical Approach

(2010) Simon P. Jones et al.   CHEMISTRY-A EUROPEAN JOURNAL

Ability to Adapt: Different Generations of PAMAM Dendrimers Show Different Behaviors in Binding siRNA

(2010) Giovanni M. Pavan et al.   JOURNAL OF PHYSICAL CHEMISTRY B

DNA Compaction by a Dendrimer

(2010) Bidisha Nandy et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Complexation of siRNA with Dendrimer: A Molecular Modeling Approach

(2010) V. Vasumathi et al.   MACROMOLECULES

Generation-Dependent Molecular Recognition Controls Self-Assembly in Supramolecular Dendron−Virus Complexes

(2010) Giovanni Doni et al.   NANO LETTERS

Self-assembly and optically triggered disassembly of hierarchical dendron–virus complexes

(2010) Mauri A. Kostiainen et al.   Nature Chemistry

The influence of dendron's architecture on the “rigid” and “flexible” behaviour in binding DNA—a modelling study

(2010) Giovanni M. Pavan et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Coarse-grained molecular simulation of interacting dendrimers

(2010) Wen-de Tian et al.   Soft Matter

Less is more – multiscale modelling of self-assembling multivalency and its impact on DNA binding and gene delivery

(2010) Paola Posocco et al.   Chemical Science

Soluble Polymer Carriers for the Treatment of Cancer: The Importance of Molecular Architecture

(2009) Megan E. Fox et al.   ACCOUNTS OF CHEMICAL RESEARCH

“On-Off” Multivalent Recognition: Degradable Dendrons for Temporary High-Affinity DNA Binding

(2009) Daniel J. Welsh et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Gene delivery using functional dendritic polymers

(2009) Constantinos M Paleos et al.   Expert Opinion on Drug Delivery

Structure of polyamidoamide dendrimers up to limiting generations: A mesoscale description

(2009) Prabal K. Maiti et al.   JOURNAL OF CHEMICAL PHYSICS

In quest of a systematic framework for unifying and defining nanoscience

(2009) Donald A. Tomalia   JOURNAL OF NANOPARTICLE RESEARCH

Molecular Dynamics Simulations of a Charged Dendrimer in Multivalent Salt Solution

(2009) Wen-de Tian et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Modeling the Multivalent Recognition between Dendritic Molecules and DNA: Understanding How Ligand “Sacrifice” and Screening Can Enhance Binding

(2009) Giovanni M. Pavan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

PAMAM Dendrimers Undergo pH Responsive Conformational Changes without Swelling

(2009) Yi Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dendrons/dendrimers: quantized, nano-element like building blocks for soft-soft and soft-hard nano-compound synthesis

(2009) Donald A. Tomalia   Soft Matter

Nonviral Vectors for Gene Delivery

(2008) Meredith A. Mintzer et al.   CHEMICAL REVIEWS

Dendrimers and the Double Helix - From DNA Binding Towards Gene Therapy

(2008) David Smith   CURRENT TOPICS IN MEDICINAL CHEMISTRY