Computational design principles for the discovery of bioactive dendrimers: [s]-triazines and other examples

Dendrimers and dendrons for siRNA binding: computational insights

(2015) G.M. Pavan et al.   JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

A molecular dynamics simulation study on the effect of lipid substitution on polyethylenimine mediated siRNA complexation

(2013) Chongbo Sun et al.   BIOMATERIALS

Combining metadynamics simulation and experiments to characterize dendrimers in solution

(2013) Giovanni M. Pavan et al.   Soft Matter

Targeting the Blind Spot of Polycationic Nanocarrier-Based siRNA Delivery

(2012) Mengyao Zheng et al.   ACS Nano

Gadolinium MRI Contrast Agents Based on Triazine Dendrimers: Relaxivity and In Vivo Pharmacokinetics

(2012) Jongdoo Lim et al.   BIOCONJUGATE CHEMISTRY

Probing the Effects of Lipid Substitution on Polycation Mediated DNA Aggregation: A Molecular Dynamics Simulations Study

(2012) Chongbo Sun et al.   BIOMACROMOLECULES

Theoretical and computational studies of dendrimers as delivery vectors

(2012) Wen-de Tian et al.   CHEMICAL SOCIETY REVIEWS

Force Biased Molecular Dynamics Simulation Study of Effect of Dendrimer Generation on Interaction with DNA

(2012) Bidisha Nandy et al.   Journal of Chemical Theory and Computation

Experimental and Computational Evidence for an Inversion in Guest Capacity in High-Generation Triazine Dendrimer Hosts

(2012) Jongdoo Lim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ion-Selective Controlled Assembly of Dendrimer-Based Functional Nanofibers and Their Ionic-Competitive Disassembly

(2012) Matteo Garzoni et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Antitumor Activity and Molecular Dynamics Simulations of Paclitaxel-Laden Triazine Dendrimers

(2012) Jongdoo Lim et al.   MOLECULAR PHARMACEUTICS

pH-responsive dendrimers interacting with lipid membranes

(2012) Wen-de Tian et al.   Soft Matter

Insights into the endosomal escape mechanism via investigation of dendrimer–membrane interactions

(2012) Wen-de Tian et al.   Soft Matter

Computational design principles for bioactive dendrimer based constructs as antagonists of the TLR4-MD-2-LPS complex

(2011) Teresa Barata et al.   BIOMATERIALS

Elucidating the molecular mechanism of PAMAM–siRNA dendriplex self-assembly: Effect of dendrimer charge density

(2011) Linda B. Jensen et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Molecular modeling and in vivo imaging can identify successful flexible triazine dendrimer-based siRNA delivery systems

(2011) Olivia M. Merkel et al.   JOURNAL OF CONTROLLED RELEASE

Dendritic effects: dependency of dendritic nano-periodic property patterns on critical nanoscale design parameters (CNDPs)

(2011) Donald A. Tomalia   NEW JOURNAL OF CHEMISTRY

Quantifying the Effect of Surface Ligands on Dendron-DNA Interactions: Insights into Multivalency through a Combined Experimental and Theoretical Approach

(2010) Simon P. Jones et al.   CHEMISTRY-A EUROPEAN JOURNAL

Ability to Adapt: Different Generations of PAMAM Dendrimers Show Different Behaviors in Binding siRNA

(2010) Giovanni M. Pavan et al.   JOURNAL OF PHYSICAL CHEMISTRY B

DNA Compaction by a Dendrimer

(2010) Bidisha Nandy et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Complexation of a Linear Polyelectrolyte with a Charged Dendrimer: Polyelectrolyte Stiffness Effects

(2010) Wen-de Tian et al.   MACROMOLECULES

Biological Assessment of Triazine Dendrimer: Toxicological Profiles, Solution Behavior, Biodistribution, Drug Release and Efficacy in a PEGylated, Paclitaxel Construct

(2010) Su-Tang Lo et al.   MOLECULAR PHARMACEUTICS

Generation-Dependent Molecular Recognition Controls Self-Assembly in Supramolecular Dendron−Virus Complexes

(2010) Giovanni Doni et al.   NANO LETTERS

The influence of dendron's architecture on the “rigid” and “flexible” behaviour in binding DNA—a modelling study

(2010) Giovanni M. Pavan et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Coarse-grained molecular simulation of interacting dendrimers

(2010) Wen-de Tian et al.   Soft Matter

Design, Synthesis, Characterization, and Biological Evaluation of Triazine Dendrimers Bearing Paclitaxel Using Ester and Ester/Disulfide Linkages

(2009) Jongdoo Lim et al.   BIOCONJUGATE CHEMISTRY

Synthesis and Characterization of Anionic Triazine Dendrimers with a Labile Disulfide Core

(2009) Wen Zhang et al.   ISRAEL JOURNAL OF CHEMISTRY

Structure of polyamidoamide dendrimers up to limiting generations: A mesoscale description

(2009) Prabal K. Maiti et al.   JOURNAL OF CHEMICAL PHYSICS

In quest of a systematic framework for unifying and defining nanoscience

(2009) Donald A. Tomalia   JOURNAL OF NANOPARTICLE RESEARCH

Modeling the Multivalent Recognition between Dendritic Molecules and DNA: Understanding How Ligand “Sacrifice” and Screening Can Enhance Binding

(2009) Giovanni M. Pavan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

PAMAM Dendrimers Undergo pH Responsive Conformational Changes without Swelling

(2009) Yi Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Electrophoretic Behavior of Anionic Triazine and PAMAM Dendrimers: Methods for Improving Resolution and Assessing Purity Using Capillary Electrophoresis

(2009) Sanjiv Lalwani et al.   MACROMOLECULES

Charged Dendrimers on Lipid Bilayer Membranes: Insight through Dissipative Particle Dynamics Simulations

(2009) Li-Tang Yan et al.   MACROMOLECULES

Mimicking PAMAM Dendrimers with Amphoteric, Hybrid Triazine Dendrimers: A Comparison of Dispersity and Stability

(2009) Sanjiv Lalwani et al.   MACROMOLECULES

Dendrons/dendrimers: quantized, nano-element like building blocks for soft-soft and soft-hard nano-compound synthesis

(2009) Donald A. Tomalia   Soft Matter

The Role of the Size and Number of Polyethylene Glycol Chains in the Biodistribution and Tumor Localization of Triazine Dendrimers

(2008) Jongdoo Lim et al.   MOLECULAR PHARMACEUTICS

Synthesis of Water-Soluble Dendrimers Based on Melamine Bearing 16 Paclitaxel Groups

(2007) Jongdoo Lim et al.   ORGANIC LETTERS