MT1-Selective Melatonin Receptor Ligands: Synthesis, Pharmacological Evaluation, and Molecular Dynamics Investigation ofN-{[(3-O-Substituted)anilino]alkyl}amides

Recent Progress in the Development of Agonists and Antagonists for Melatonin Receptors

(2012) D. P. Zlotos   CURRENT MEDICINAL CHEMISTRY

N-Acetyl-5-arylalkoxytryptamine Analogs: Probing the Melatonin Receptors for MT1-Selectivity

(2011) Christian Markl et al.   ARCHIV DER PHARMAZIE

Bivalent ligand approach on N-{2-[(3-methoxyphenyl)methylamino]ethyl}acetamide: Synthesis, binding affinity and intrinsic activity for MT1 and MT2 melatonin receptors

(2011) Gilberto Spadoni et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Structural insights into agonist-induced activation of G-protein-coupled receptors

(2011) Xavier Deupi et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Promotion of Non-Rapid Eye Movement Sleep and Activation of Reticular Thalamic Neurons by a Novel MT2 Melatonin Receptor Ligand

(2011) R. Ochoa-Sanchez et al.   JOURNAL OF NEUROSCIENCE

Melatonin and its analogs in insomnia and depression

(2011) Daniel P. Cardinali et al.   JOURNAL OF PINEAL RESEARCH

Crystal structure of the β2 adrenergic receptor–Gs protein complex

(2011) Søren G. F. Rasmussen et al.   NATURE

Reorganizing the protein space at the Universal Protein Resource (UniProt)

(2011)   NUCLEIC ACIDS RESEARCH

Design, synthesis and pharmacological evaluation of novel naphthalenic derivatives as selective MT1 melatoninergic ligands

(2010) Christophe Mésangeau et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Melatonin Receptor Agonists: New Options for Insomnia and Depression Treatment

(2010) Gilberto Spadoni et al.   CNS Neuroscience & Therapeutics

Recent advances in the development of melatonin MT1and MT2receptor agonists

(2010) Marco Mor et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Ligand Binding and Subtype Selectivity of the Human A2AAdenosine Receptor

(2010) Veli-Pekka Jaakola et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A method for the preparation of [13C6]-labelled 2-substituted naphthalenes

(2010) George J. Ellames et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Erratum: Agomelatine, the first melatonergic antidepressant: discovery, characterization and development

(2010) Christian de Bodinat et al.   NATURE REVIEWS DRUG DISCOVERY

International Union of Basic and Clinical Pharmacology. LXXV. Nomenclature, Classification, and Pharmacology of G Protein-Coupled Melatonin Receptors

(2010) M. L. Dubocovich et al.   PHARMACOLOGICAL REVIEWS

N-(Anilinoethyl)amides: Design and Synthesis of Metabolically Stable, Selective Melatonin Receptor Ligands

(2009) Silvia Rivara et al.   ChemMedChem

Pharmacology of Ramelteon, a Selective MT1/MT2Receptor Agonist: A Novel Therapeutic Drug for Sleep Disorders

(2009) Masaomi Miyamoto   CNS Neuroscience & Therapeutics

Multivalent-Based Drug Design Applied to Serotonin 5-HT4 Receptor Oligomers

(2009) Frank Lezoualc'h et al.   CURRENT PHARMACEUTICAL DESIGN

Melatonin as a potential therapeutic agent in psychiatric illness

(2009) Maria D. Maldonado et al.   HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL

Potential roles of melatonin and chronotherapy among the new trends in hypertension treatment

(2009) Fedor Simko et al.   JOURNAL OF PINEAL RESEARCH

Melatonin: A hormone that modulates pain

(2009) Mónica Ambriz-Tututi et al.   LIFE SCIENCES

Neuroprotection by Radical Avoidance: Search for Suitable Agents

(2009) Rüdiger Hardeland   MOLECULES

Melatonin modulates visual function and cell viability in the mouse retina via the MT1 melatonin receptor

(2009) K. Baba et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Melatonin receptors, heterodimerization, signal transduction and binding sites: what's new?

(2008) R Jockers et al.   BRITISH JOURNAL OF PHARMACOLOGY

Melatonin Receptor Agonists: SAR and Applications to the Treatment of Sleep-Wake Disorders

(2008) Silvia Rivara et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion

(2008) Valeriya Lyssenko et al.   NATURE GENETICS

A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk

(2008) Nabila Bouatia-Naji et al.   NATURE GENETICS

Physiological effects of melatonin: Role of melatonin receptors and signal transduction pathways

(2008) S PANDIPERUMAL et al.   PROGRESS IN NEUROBIOLOGY

The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist

(2008) V.-P. Jaakola et al.   SCIENCE