Melatonin and its analogs in insomnia and depression

Efficacy and Safety of 6-Month Nightly Ramelteon Administration in Adults with Chronic Primary Insomnia

(2017) Geert Mayer et al.   SLEEP

A Closer Look at the High Affinity Benzodiazepine Binding Site on GABAA Receptors

(2012) Erwin Sigel et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

The Emerging Role of Melatonin Agonists in the Treatment of Major Depression: Focus on Agomelatine

(2011) Domenico De Berardis et al.   CNS & Neurological Disorders-Drug Targets

Metabolism of Benzodiazepine and Non-Benzodiazepine Anxiolytic-Hypnotic Drugs: an Analytical Point of View

(2011) Roberto Mandrioli et al.   CURRENT DRUG METABOLISM

Tasimelteon for insomnia

(2011) D Alan Lankford   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Efficacy and safety of ramelteon in Japanese adults with chronic insomnia: a randomized, double-blind, placebo-controlled study

(2011) Naohisa Uchimura et al.   Expert Review of Neurotherapeutics

Melatonin has membrane receptor-independent hypnotic action on neurons: an hypothesis

(2011) James E. Jan et al.   JOURNAL OF PINEAL RESEARCH

Insomnia: Neurophysiological and NeuropsychologicalApproaches

(2011) Célyne H. Bastien   NEUROPSYCHOLOGY REVIEW

Long-term safety and efficacy of ramelteon in Japanese patients with chronic insomnia

(2011) Makoto Uchiyama et al.   SLEEP MEDICINE

Jet lag, circadian rhythm sleep disturbances, and depression: the role of melatonin and its analogs

(2010) Venkatramanujam Srinivasan et al.   ADVANCES IN THERAPY

Aquaporin-1 in blood vessels of rat circumventricular organs

(2010) Alan J. Wilson et al.   CELL AND TISSUE RESEARCH

Agomelatine in the Treatment of Major Depressive Disorder

(2010) Sidney H. Kennedy et al.   CNS DRUGS

Prolonged release melatonin in the treatment of primary insomnia: evaluation of the age cut-off for short- and long-term response

(2010) Alan G. Wade et al.   CURRENT MEDICAL RESEARCH AND OPINION

A randomized, placebo-controlled study of adjunctive ramelteon in ambulatory bipolar I disorder with manic symptoms and sleep disturbance

(2010) Susan L. McElroy et al.   INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY

Efficacy of the Novel Antidepressant Agomelatine on the Circadian Rest-Activity Cycle and Depressive and Anxiety Symptoms in Patients With Major Depressive Disorder

(2010) Siegfried Kasper et al.   JOURNAL OF CLINICAL PSYCHIATRY

Review: The antidepressant agomelatine improves the quality of life of depressed patients: implications for remission

(2010) Pierre-Michel Llorca   JOURNAL OF PSYCHOPHARMACOLOGY

British Association for Psychopharmacology consensus statement on evidence-based treatment of insomnia, parasomnias and circadian rhythm disorders

(2010) SJ Wilson et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Erratum: Agomelatine, the first melatonergic antidepressant: discovery, characterization and development

(2010) Christian de Bodinat et al.   NATURE REVIEWS DRUG DISCOVERY

International Union of Basic and Clinical Pharmacology. LXXV. Nomenclature, Classification, and Pharmacology of G Protein-Coupled Melatonin Receptors

(2010) M. L. Dubocovich et al.   PHARMACOLOGICAL REVIEWS

Melatonin—A pleiotropic, orchestrating regulator molecule

(2010) Rüdiger Hardeland et al.   PROGRESS IN NEUROBIOLOGY

Prevention of depression and sleep disturbances in elderly with memory-problems by activation of the biological clock with light - a randomized clinical trial

(2010) Els IS Most et al.   Trials

Ramelteon: a review of its therapeutic potential in sleep disorders

(2009) Seithikurippu R. Pandi-Perumal et al.   ADVANCES IN THERAPY

The role of eszopiclone in the treatment of insomnia

(2009) Anna K. Morin et al.   ADVANCES IN THERAPY

Pharmacology of Ramelteon, a Selective MT1/MT2Receptor Agonist: A Novel Therapeutic Drug for Sleep Disorders

(2009) Masaomi Miyamoto   CNS Neuroscience & Therapeutics

Comparative Tolerability of Newer Agents for Insomnia

(2009) Gary Zammit   DRUG SAFETY

Antagonism of serotonergic 5-HT2A/2Creceptors: mutual improvement of sleep, cognition and mood?

(2009) H.-P. Landolt et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Antidepressant-like effects of melatonin in the mouse chronic mild stress model

(2009) Bernardo C. Detanico et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Melatonin and Melatonergic Drugs on Sleep: Possible Mechanisms of Action

(2009) Venkataramanujan Srinivasan et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Zaleplon increases nocturnal melatonin secretion in humans

(2009) A.L. Morera et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Activation of 5-HT2C receptors acutely induces Per1 gene expression in the rat SCN in vitro

(2008) Tamara J. Varcoe et al.   BRAIN RESEARCH

Ramelteon 8 mg/d versus placebo in patients with chronic insomnia: Post hoc analysis of a 5-week trial using 50% or greater reduction in latency to persistent sleep as a measure of treatment effect

(2008) Louis Mini et al.   CLINICAL THERAPEUTICS

Eszopiclone

(2008) Philip I Hair et al.   DRUGS

Melatonin agonist tasimelteon (VEC-162) for transient insomnia after sleep-time shift: two randomised controlled multicentre trials

(2008) Shantha MW Rajaratnam et al.   LANCET

The roles of melatonin and light in the pathophysiology and treatment of circadian rhythm sleep disorders

(2008) Seithikurippu R Pandi-Perumal et al.   Nature clinical practice. Neurology